Understanding design principles of biomolecular recognition is a key question of molecular biology. Yet the enormous complexity and diversity of biological molecules hamper the efforts to gain a predictive ability for the free energy of protein-protein, protein-DNA, and protein-RNA binding. Here, using a variant of the Derrida model, we predict that for a large class of biomolecular interactions,

A large eddy simuation (LES) model is presented for simulation of spark-assisted homogeneous charge compression ignition combustion. The model is based on tabulated chemical kinetic rate for ignition and flame surface density for flame propagation, taking into account interaction between flame propagation introduced by the spark and auto-ignition due to charge compression. The model is used to sim

Background Long-term safety and efficacy data of drug-eluting stents (DESs) in saphenous vein grafts (SVGs) are lacking. This study sought to compare the clinical outcomes of DES versus bare metal stents (BMS) in SVGs. Methods We studied all stent implantations in SVGs in Sweden during 74 months between 2005 and 2011 registered in the Swedish Coronary Angiography and Angioplasty Registry. We evalu

New tools are being developed to estimate greenhouse gas (GHG) emissions from wastewater treatment plants (WWTPs). There is a trend to move from empirical factors to simple comprehensive and more complex process-based models. Thus, the main objective of this study is to demonstrate the importance of using process-based dynamic models to better evaluate GHG emissions. This is tackled by defining a

The Narodichesky region, Zhitomir Oblast, Ukraine, is situated ∼80 km from the Chernobyl Nuclear Power Plant, which exploded in 1986 and polluted the environment. A previous study found that children living in villages with high activity of (137)Cesium (Cs) in the soil had decreased levels of hemoglobin, erythrocytes and thrombocytes. These findings motivated the present study that used a more com

Key locations within an extensive area of the northeastern Tibetan Plateau, centred on Bayan Har Shan, have been mapped to distinguish glacial from non-glacial deposits. Prior work suggests palaeo-glaciers ranging from valley glaciers and local ice caps in the highest mountains to a regional or even plateau-scale ice sheet. New field data show that glacial deposits are abundant in high mountain ar

Waterpipe smoking is becoming increasingly popular worldwide. Research has shown that cigarette smoke, in addition to hundreds of carcinogenic and otherwise toxic compounds, may also contain compounds of microbiological origin. In the present study we analyzed waterpipe smoke for some microbial compounds. Both of the two markers studied, viz 3-hydroxy fatty acids of bacterial lipopolysaccharide (L

We construct a variational formulation for the problem of interpolating seismic data in the case of missing traces. We assume that we have derivative information available at the traces. The variational problem is essentially the minimization of the integral over the smallest eigenvalue of the structure tensor associated with the interpolated data. This has the physical meaning of penalizing the l

Many migratory bird species have advanced their spring arrival during the latest decades, most probably due to climate change. However, studies on migratory phenology in the period before recent global warming are scarce. We have analyzed a historical dataset (1873-1917) of spring arrival to southern and central Sweden of 14 migratory bird species. In addition, we have used relative differences be

Background. Sepsis is a serious and common condition with high mortality and morbidity. The public awareness, knowledge, and perception of sepsis in Sweden are unknown. Methods. A survey was performed using an online interview distributed to adults, aged 18-74, between March 6 and 9, 2015. Results. A total of 1001 people responded to the survey. Twenty-one percent of participants had heard of seps

Populärvetenskaplig artikel om medierapporteringen om Titanics undergång.

The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Therefore, recombinant human EPO (rhEPO) is used to treat anemia in cancer patients, but some studies have reported that rhEPO treatment might promote tumor progression. Additionally, EPOR expression has been detected in various cancer forms. Here, we confirm EPOR expression in several breast ca

A systematic study of the odd-intrinsic parity sector of QCD is presented. We briefly describe different applications including pi(0) -> gamma gamma decay, muonic g -2 factor and test of new holographic conjectures.

Giant bamboo plantations are currently being established in the Southern Africa region and can be considered as potential lignocellulosic feedstock for the production of second generation bioethanol. In this study, giant bamboo internodal material was subjected to sulphur dioxide (SO2) impregnated steam pretreatment prior to enzymatic hydrolysis. The effect of temperature, residence time, and acid

Dissipative particle dynamics with energy conversion (DPDe) is a simulation technique that has been used to model thermal transport characteristics and heat transfer at mesoscale. This study shows further development of the DPDe method capturing solid/liquid phase-change phenomena and its application to water freezing in a parallel-plate straight channel. In this work, the weighting functions of t

Palsa mires, nutrient poor permafrost peatlands common in subarctic regions, store a significant amount of carbon (C) and it has been hypothesized their net ecosystem C balance (NECB) is sensitive to climate change. Over two years we measured the NECB for Stordalen palsa mire and found it to accumulate 46 g C m(-2) yr(-1). While Stordalen NECB is comparable to nutrient poor peatlands without perma

Contemporary methods of atrial flutter (AFL), atrial tachycardia (AT), and atrial fibrillation (AF) monitoring, although superior to the standard 12-lead ECG and symptom-based monitoring, are unable to accurately discriminate between AF, AFL and AT. Thus, there is a need to develop accurate, automated, and comprehensive atrial arrhythmia detection algorithms using standard ECG recorders. To this e