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Constraining the process of Eoarchean TTG formation in the Itsaq Gneiss Complex, southern West Greenland

We present new major and trace element, high-precision high-field-strength-element, hafnium and neodymium isotope data for well preserved Eoarchean TTGs within the Itsaq Gneiss Complex (IGC) of southern West Greenland. These data are combined with thermodynamic model predictions of partial melting and fractional crystallization to gain new insights into continental crust formation in the Archean.

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals

Azimuthal correlations of electrons from heavy-flavor decay with hadrons in p plus p and Au plus Au collisions at root s(NN)=200 GeV

Measurements of electrons from the decay of open-heavy-flavor mesons have shown that the yields are suppressed in Au+Au collisions compared to expectations from binary-scaled p+p collisions. These measurements indicate that charm and bottom quarks interact with the hot dense matter produced in heavy-ion collisions much more than expected. Here we extend these studies to two-particle correlations w

Causes of death and metastatic patterns in Swedish cancer patients

This thesis aimed to investigate possibilities to utilize death certificates in cancer epidemiology by analyzing nationwide databases from Sweden. Excessive information is available when investigating causes of death in cancer patients, including comorbidities and metastatic patterns. We used the Swedish Family- Cancer Database, which includes data from e.g. the Cause of Death Register and the Can

Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

OBJECTIVE-Mutations in the hepatocyte nuclear factor (HNF)-1 alpha, HNF-4 alpha, glucokinase (GCK), and HNF-1 beta genes cause maturity-onset diabetes of the young (MODY), but it is not known whether common variants in these genes predict future type 2 diabetes. RESEARCH DESIGN AND METHODS-We tested 14 previously associated polymorphisms in HNF-1 alpha, HNF-4 alpha, GCK, and HNF-1 beta for associa

Novel pyrazolate-based copper(II) [2 x 2] grid complexes: Synthesis, structure and properties

5-Acetyl-substituted pyrazole-3-carboxylic acid (H2L) forms [2 x 2] grid-like tetranuclear Cu(II) complexes with four five-coordinated copper(II) ions bridged by pyrazolate groups. Despite a significant dissociation of [Cu4L4(H2O)(4)]center dot 4H(2)O (1) in aqueous solution(1), it was possible to substitute the coordinated water molecules by pyridine ligands or azide anions. The resulting tetranu

Charged hadron multiplicity fluctuations in Au plus Au and Cu plus Cu collisions from s(NN)=22.5 to 200 GeV

A comprehensive survey of event-by-event fluctuations of charged hadron multiplicity in relativistic heavy ions is presented. The survey covers Au+Au collisions at s(NN)=62.4 and 200 GeV, and Cu+Cu collisions at s(NN)=22.5,62.4, and 200 GeV. Fluctuations are measured as a function of collision centrality, transverse momentum range, and charge sign. After correcting for nondynamical fluctuations du

Exploring the Grey Zone between Type 1 and Type 2 Diabetes

Popular Abstract in Swedish Diabetes kännetecknas av förhöjda halter av glukos i blodet och flera vanliga former förekommer. Typ 1 (T1D) diabetes är vanligast förekommande hos barnoch ungdomar och karakteriseras av att de insulin producerande cellerna (s.k. betacellerna) förstörs av kroppens eget immunförsvar, en autoimmun reaktion. Patienter med T1D diabetes kräver insulin för överlevnad och har T1D is most common in children and young adults and is characterized by autoimmune destruction of insulin producing pancreatic beta cells, presence of certain risk genotypes such as HLA-DQB1, INS VNTR, PTPN22 and need of insulin for survival. In adults the same situation is often referred to as Latent Autoimmune Diabetes in Adults (LADA), with age at onset after 35 years and non-insulin requiring

Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.

The progressive development of Alzheimer's disease (AD) pathology follows a spatiotemporal pattern in the human brain. In a transgenic (Tg) mouse model of AD expressing amyloid precursor protein (APP) with the arctic (E693G) mutation, pathology spreads along anatomically connected structures. Amyloid-β (Aβ) pathology first appears in the subiculum and is later detected in interconnected brain regi

Event structure, conceptual spaces and the semantics of verbs

The aim of this paper is to integrate spatial cognition with lexical semantics. We develop cognitive models of actions and events based on conceptual spaces and vectors on them. The models are then used to present a semantic theory of verbs. We propose a two-vector model of events including a force vector and a result vector. We argue that our framework provides a unified account for a multiplicit

Characterization of macroporous carbon-cryostructured particle gel, an adsorbent for small organic molecules

Preparation of a new type of cryostructured carbon particle macroporous gel with one-step sub-zero cross-linking was studied in this work. Aggregation of nano-and micro-particles of poly(N-isopropylacrylamide-co-allylamine) was used to form a polymeric network to integrate activated carbon particles. The cryostructured particle gel was compared with the conventional composite cryogel. The unique m

Normative, authententic and altruistic fruit and vegetable consumption as weblog discourses

Abstract in Undetermined The Internet is a growing information and communication channel for health- and diet-related issues. Keeping updated on the fruit- and vegetable-related (F&V) discourses among laypeople is important for health communicators in order to promote F&V consumption through tailored health messages. The aim of the present study was to identify F&V-related discourses i

Electronic structure calculations of mercury mobilization from mineral phases and photocatalytic removal from water and the atmosphere

Mercury is a hazardous environmental pollutant mobilized from natural sources, and anthropogenically contaminated and disturbed areas. Current methods to assess mobility and environmental impact are mainly based on field measurements, soil monitoring, and kinetic modelling. In order to understand in detail the extent to which different mineral sources can give rise to mercury release it is necessa

Doubly dispossessed by accumulation: Egyptian fishing communities between enclosed lakes and a rising sea

In a corner of the Egyptian revolutionary drama, the fisherfolk of the northern Nile Delta have begun to organise. They suffer an indicative predicament. The two great lagoons of Borullus and Manzala have largely been enclosed by fish farms as the Mubarak regime sought to expand Egypt's aquaculture industry. On the other hand, the sea is threatening to submerge the ground on which the very same fi

Design of sanitary landfills in Jordan for sustainable solid waste management

Municipal solid waste is one of the major environmental problems in Jordan. The World Bank visibility study (2004) showed that the rate of production of solid waste in Jordan was estimated annually of about 1.46 million ton, and is expected to reach 2.5 million ton by the year 2015 with a generation of 0.9/kg/capita/day. This solid waste volume is still increasing at high rates due to the rapid in

A Coding-Cost Framework for Super-Resolution Motion Layer Decomposition

We consider the problem of decomposing a video sequence into a superposition of (a given number of) moving layers. For this problem, we propose an energy minimization approach based on the coding cost. Our contributions affect both the model (what is minimized) and the algorithmic side (how it is minimized). The novelty of the coding-cost model is the inclusion of a refined model of the image form

Ocean heat transport into the Arctic in the twentieth and twenty-first century in EC-Earth

The ocean heat transport into the Arctic and the heat budget of the Barents Sea are analyzed in an ensemble of historical and future climate simulations performed with the global coupled climate model EC-Earth. The zonally integrated northward heat flux in the ocean at 70A degrees N is strongly enhanced and compensates for a reduction of its atmospheric counterpart in the twenty first century. Alt