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Normalisation of glucose metabolism by exendin-4 in the chronic phase after stroke promotes functional recovery in male diabetic mice

Background and Purpose: Glucagon-like peptide-1 (GLP-1) receptor activation decreases stroke risk in people with Type 2 diabetes (T2D), while animal studies have shown the efficacy of this strategy to counteract stroke-induced acute brain damage. However, whether GLP-1 receptor activation also improves recovery in the chronic phase after stroke is unknown. We investigated whether post-acute, chron

Anterior uveitis in patients with spondyloarthritis treated with secukinumab or tumour necrosis factor inhibitors in routine care : Does the choice of biological therapy matter?

Background: The effect of interleukin 17-inhibitors on anterior uveitis (AU) in spondyloarthritis (SpA) is poorly understood. This study aimed to compare the risk of AU during treatment with secukinumab versus tumour necrosis factor inhibitors (TNFi). Methods: Patients with SpA starting secukinumab or a TNFi 2015 through 2018 were identified in the Swedish Rheumatology Quality Register. Occurrence

Modeling and forecasting of metrological factors using arch process under different errors distribution specification

Various weather phenomenon are difficult to model and forecast with high precision. This study has modelled and forecasted the various parameter namely maximum and minimum temperature, morning and evening relative humidity using parametric models namely Autoregressive Integrated Moving Average (ARIMA) and Generalized Autoregressive conditional heteroskedasticity (GARCH)) models. The data consisted

Calcein Fluorescence Quenching to Measure Plasma Membrane Water Flux in Live Mammalian Cells

Aquaporins (AQPs) are membrane channel proteins that facilitate the movement of water down osmotic gradients across biological membranes. This protocol allows measurements of AQP-mediated water transport across the plasma membrane of live mammalian cells. Calcein is a fluorescent dye that is quenched in a concentration-dependent manner. Therefore, on short timescales, its concentration-dependent f

The role of fitbits in corporate wellness programs : Does step count matter?

Striving to promote the health and well-being of their workforce and decrease insurance expenditures, many organizations are incorporating wearable fitness trackers into their corporate wellness programs. Research suggests that these devices encourage individuals to make healthier choices; however, little is known about the drivers and impact of fitness trackers on employee health and wellbeing. W

Introduction : Masculinities, gender equality, crisis management and the rescue services: Contested terrains and challenges

In this introduction we provide an overview of research on gender issues in the rescue services in combination with introducing the different contributions in this book. The overview is primarily concerned with three national contexts, the US, the UK and Sweden, and we focus on the most prevalent themes in the literature as well as pointing out under-researched areas. The empirical contributions i

Proton-Pump Inhibitor Use and the Risk of Community-Associated Clostridium difficile Infection

Background: Proton-pump inhibitors (PPIs) have been reported to increase the risk of community-associated Clostridium difficile infection (CDI), but the association remains disputed. Methods: A nationwide cohort study among adults in Denmark, 2010-2013, linking register data on C. difficile testing, filled prescriptions, and patient characteristics. All incident episodes of community-associated CD

Ground- And excited-state characteristics in photovoltaic polymer N2200

As a classical polymer acceptor material, N2200 has received extensive attention and research in the field of polymer solar cells (PSCs). However, the intrinsic properties of ground- and excited-states in N2200, which are critical for the application of N2200 in PSCs, remain poorly understood. In this work, the ground- and excited-state properties of N2200 solution and film were studied by steady-

Experience of using video support by prehospital emergency care physician in ambulance care - an interview study with prehospital emergency nurses in Sweden

Introduction: When in need of emergency care and ambulance services, the ambulance nurse is often the first point of contact for the patient with healthcare. This role requires comprehensive knowledge of the ambulance nurse to be able to assign the right level of care and, if necessary, to provide self-care advice for patients with no further conveyance to hospital. Recently, an application was de

Modular Design and Integration of In-Cycle Closed-Loop Combustion Controllers for a Wide-Range of Operating Conditions

This paper investigates how multiple in-cycle closed-loop combustion controllers can be integrated for a seamless operation under a wide-range of operating conditions. The stochastic cyclic variations of the combustion can be successfully compensated by the adjustment of the fuel injection pulses within the same cycle. The feedback information and controllability obtained relies on the different o

Quantication of FPGA Requirements for Closed-Loop Combustion Control Implementation

This paper investigates the quantification of FPGA resources for the implementation of closed-loop combustion control algorithms. Specifically, the study focuses on methods for their in-cycle execution and control of the combustion in real-time. A National Instruments Xilinx Virtex-5 platform was used for the quantification of the resources.Closed-loop combustion control obtains feedback from fast

Toward a Stable Global Noctuidae (Lepidoptera) Taxonomy

Noctuidae are one of the world's most diverse, ecologically successful, and economically important animal lineages with over 12,000 species in ∼1,150 genera. We inferred a phylogeny using eight protein-coding genes for the global fauna, greatly expanding upon previous attempts to stabilize Noctuidae higher classification by sampling 341 genera (nearly half represented by their type species) repres

Heat load forecasting using adaptive temporal hierarchies

Heat load forecasts are crucial for energy operators in order to optimize the energy production at district heating plants for the coming hours. Furthermore, forecasts of heat load are needed for optimized control of the district heating network since a lower temperature reduces the heat loss, but the required heat supply at the end-users puts a lower limit on the temperature level. Consequently,

Degradation of desphenyl chloridazon in a novel synergetic electrocatalytic system with Ni–Sb–SnO2/Ti anode and PEDOT/PSS-CNTs modified air diffusion cathode

This study explored the depth treatment of desphenly chloridazon (DPC) wastewater by a novel synergetic dual-electrodes electrocatalytic (SDEs) system which consisted of Ni–Sb–SnO2/Ti anode (NSSTA) and PEDOT/PSS-CNTs modified activated carbon air diffusion cathode (PP-CNTs AC ADC). NSSTA exhibited an enhanced capability to produce reactive oxygen species (·OH and O3), its O3 production increased t

Altering Radiation Response with Time, Volume and Fractionation

Radioresistance, the failure to achieve a desired outcome, is an obstacle in clinical radiotherapy. In this thesis we investigate factors affecting radioresistance and strategies to overcome it, both with established clinical approaches and by using novel pre-clinical discoveries. Study I & II concern the impact of tumour volume in patients with oropharyngeal cancer. In a large, pooled cohort

Low-band MIMO antenna for smartphones with robust performance to user interaction

This letter proposes a two-port MIMO smartphone antenna for frequency bands below 1 GHz, which is robust to user effects. The design is achieved by first analyzing the characteristic modes of a chassis that includes the large screen. Two modes predicted to be less affected by the user than other commonly used modes are selected. The modal currents and near-fields of the two desired modes then guid

Complex-valued (p,q)-harmonic morphisms from Riemannian manifolds

We introduce the natural notion of (p,q)-harmonic morphisms between Riemannian manifolds. This unifies several theories that have been studied during the last decades. We then study the special case when the maps involved are complex-valued. For these we find a characterisation and provide new non-trivial examples in important cases.