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Self-Service Business Analytics and the Path to Insights : Integrating Resources for Generating Insights

The nature of today’s business demands that Business Analytics (BA) extends to an operational level to better support employees in their decision-making. This is noticeable from the constant requests for new reports and changes in old ones at different employee levels. As a result, BA specialists or other power-users in functional departments are “bombarded” by these requests, and it becomes more

Visible light induction of an electron paramagnetic resonance split signal in photosystem II in the S 2 state reveals the importance of charges in the oxygen-evolving center during catalysis : A unifying model

Cryogenic illumination of Photosystem II (PSII) can lead to the trapping of the metastable radical Y Z •, the radical form of the redox-active tyrosine residue D1-Tyr161 (known as Y Z). Magnetic interaction between this radical and the CaMn 4 cluster of PSII gives rise to so-called split electron paramagnetic resonance (EPR) signals with characteristics that are dependent on the S state. We report

The formation of the split EPR signal from the S3 state of Photosystem II does not involve primary charge separation

Metalloradical EPR signals have been found in intact Photosystem II at cryogenic temperatures. They reflect the light-driven formation of the tyrosine Z radical (YZ) in magnetic interaction with the CaMn4 cluster in a particular S state. These so-called split EPR signals, induced at cryogenic temperatures, provide means to study the otherwise transient YZ and to probe the S states with EPR spectro

Split EPR signals from photosystem II are modified by methanol, reflecting S state-dependent binding and alterations in the magnetic coupling in the CaMn4 cluster

Methanol binds to the CaMn4 cluster in photosystem II (PSII). Here we report the methanol dependence of the split EPR signals originating from the magnetic interaction between the CaMn4 cluster and the Y Z· radical in PSII which are induced by illumination at 5 K. We found that the magnitudes of the "split S1" and "split S3" signals induced in the S1 and S 3 states of PSII centers, respectively, a

Impact of AgNPs on seed germination and seedling growth : A focus study on its antibacterial potential against clavibacter michiganensis subsp. Michiganensis infection in solanum lycopersicum

This study investigated the effect of biogenic AgNPs on seed germination and seedling growth of Solanum lycopersicum. Treatment with silver nanoparticles (AgNPs) showed a significantly high germination rate and seedling growth compared to untreated seeds. Furthermore, its bactericidal effect against bacterial pathogen Clavibacter michiganensis subsp. michiganensis (cmm) infection in Solanum lycope

Fundamental Frequency in Feedback Words in Swedish

An investigation of the fundamental frequency in Swedish feedback words is presented. It is hypothesised that the F0-pattern differs between words signalling positive and negative feedback-i.e. agreement and disagreement with the utterance of the preceding speaker. When imitating the contrast, the negative feedback word nej 'no' is often produced with a falling F0, stretching over a larger range,

Inhibitor incidence in an unselected cohort of previously untreated patients with severe haemophilia B : a PedNet study

The incidence of FIX inhibitors in severe hemophilia B (SHB) is not well defined. Frequencies of 3-5% have been reported but most studies to date were small, including patients with different severities, and without prospective follow-up for inhibitor incidence. Study objective was to investigate inhibitor incidence in patients with SHB followed up to 500 exposure days (ED), the frequency of aller

Graphene-based plasmonic nanocomposites for highly enhanced solar-driven photocatalytic activities

High-efficiency photocatalysts are crucial for the removal of organic pollutants and environmental sustainability. In the present work, we report on a new low-temperature hydrothermal chemical method, assisted by ultrasonication, to synthesize disruptive plasmonic ZnO/graphene/Ag/AgI nanocomposites for solar-driven photocatalysis. The plasmonic nanocomposites were investigated by a wide range of c

Association between serum concentrations of perfluoroalkyl substances (PFAS) and expression of serum microRNAs in a cohort highly exposed to PFAS from drinking water

BACKGROUND: Perfluoroalkyl substances (PFAS) are widespread synthetic substances with various adverse health effects. Not much is known about the modes of action of PFAS toxicity, but one likely mechanism is alteration of microRNA expression.OBJECTIVES: To investigate whether PFAS exposure is associated with altered microRNA expression in serum.METHODS: We selected women from the Ronneby cohort, w

Advantage of new ventilation method for cardiopulmonary resuscitation qualitatively captured by simple respiratory mechanics models

First responders to cardiac arrest depend on cardiopulmonary resuscitation to keep patients alive. A new ventilation method, phase-controlled intermittent insufflation of oxygen, was previously shown to improve heart perfusion during cardiopulmonary resuscitation in a large-animal study, outperforming the best currently known ventilation method. This paper investigates whether the advantage of the

Ultrasmall TPGS-PLGA Hybrid Nanoparticles for Site-Specific Delivery of Antibiotics into Pseudomonas aeruginosa Biofilms in Lungs

Inhaled antibiotic treatment of cystic fibrosis-related bacterial biofilm infections is challenging because of the pathological environment of the lungs. Here, we present an "environment-adaptive" nanoparticle composed of a solid poly lactic-co-glycolic acid (PLGA) core and a mucus-inert, enzymatically cleavable shell of d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) for the site-specifi

The design of a trimodal broadside antenna element for compact massive MIMO arrays : Utilizing the Theory of Characteristic Modes

Massive multiple-input multiple-output (MIMO) arrays are becoming critical elements in cellular base station infrastructure. We utilize the theory of characteristic modes (TCM) to design a novel tri-modal broadside antenna element which is suitable for the construction of compact massive MIMOarrays. The proposed antenna element consists of three ports which is formed by reviewing an existing compa

The feasibility of using Pareto fronts for comparison of treatment planning systems and delivery techniques

Pareto optimality is a concept that formalises the trade-off between a given set of mutually contradicting objectives. A solution is said to be Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the other. A set of Pareto optimal solutions constitute the Pareto front. The Pareto concept applies well to the inverse planning process, which involves

Prospects for membrane protein crystals in NMX

Adding hydrogen atoms and protonation states to structures of membrane proteins requires successful implementation of neutron macromolecular crystallography (NMX). This information would significantly increase our fundamental understanding of the transport processes membrane proteins undertake. To grow the large crystals needed for NMX studies requires significant amounts of stable protein, but on

Staircase and other structured linear-time encodable LDPC codes : Analysis and design

We consider a family of codes which can be seen both as a special kind of serial turbo codes and as LDPC codes having a parity check matrix which is partly random and partly structured. These codes are linear-time encodable, thanks to the turbo structure, and can be decoded as LDPC codes. We provide an ensemble analysis for the waterfall region, on the line of classical results for serial turbo co