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Genetic mechanisms for stroke in young adults. A clinical perspective.

A range of cardiovascular risk factors associated with stroke are known, but they do not explain all cases of stroke. Genetic factors can be responsible for certain forms of stroke, and are further investigated in this thesis. The aims of this thesis were to study the occurrence of familial clustering of stroke, compile known stroke-associated genetic conditions for diagnostic and research genetic

The field of EU civil society: organizational resources and elite positions1

Since the turn of the Millennium, there have been extensive debates on the relationship between the European Union (EU) and civil society. EU institutions have tended to regard associations and organizations of civil society as way to counterbalance the EU’s democratic deficit and/or as a means to foster effective implementation of policies. Much research has accordingly analysed how EU discourses

The matched reassignment applied to echolocation data

Previous studies have shown that measurements of beluga whale (Delphinapterus leucas) and bottlenose dolphin (Tur-siops truncatus) echolocation signals at off-axis angles may be well modeled using a Gaussian bell function or a chirped Gaussian function as envelope. In this paper, we apply a novel technique, the matched window reassignment, for investigation of a range of models of dolphin echoloca

A multitaper reassigned spectrogram for increased time-frequency localization precision

The reassignment vectors of the matched reassigned spectrogram (MRS) have shown to be sensitive to noise, with resulting degraded precision in the time-frequency localization. In this paper we propose a multitaper reassignment (mtRS) method for estimation of time- and frequency locations of Gaussian envelope transients. We present novel expressions for the reassignment vectors with use of a non-ma

The matched reassigned cross-spectrogram for phase estimation

In this paper, the matched reassigned spectrogram is expanded into a novel matched phase reassignment (MPR) method based on the reassigned cross-spectrogram. It is shown that for two phase synchronized oscillating transient signals, the method gives perfect time-frequency (TF) localization. The MPR is thereby a TF local measure of phase synchronization and can also be used to measure phase differe

An Operational Anthropogenic CO₂ Emissions Monitoring & Verification Support Capacity : Needs and High Level Requirements for in situ Measurements

This is the third report form the CO2 Monitoring Task Force on the multiple input streams of in-situ observations that are requirement for the Copernicus CO2 Monitoring and Verification Support capacity to: (i) calibrated and validate the space component, (ii) assimilate data in the models and integrate information in the core of the system, and (iii) evaluate the output generated by the system fo

Striving against oblivion : Tombs and cemeteries in the mid-Republic

Writing as dusk fell on the mid-Republic, Ennius (238–169 BCE) purportedly remarked, ‘Kings throughout their kingship are in quest of statues and sepulchres; they build up a name and strain with all their might and main’. A poet whose verse mediated between the Greek and Roman worlds, he knew the weight of his words, and they usefully highlight the political presence of a tomb. Not that this is un

Tumour-suppressive effect of oestrogen receptor β in colorectal cancer patients, colon cancer cells, and a zebrafish model

Oestrogen receptor β (ERβ) has been suggested to have anti-proliferative and anti-tumour effects in breast and prostate cancer cells, but other studies have indicated its tumour-promoting effects. Understanding the complex effects of this receptor in different contexts requires further study. We reported that high ERβ expression is independently associated with improved prognosis in female colorec

“Science and proven experience” : How should the epistemology of medicine inform the regulation of healthcare?

The Swedish medico-legal concept of “science and proven experience” is both legally important and ambiguous. The conceptual uncertainty associated with it can hamper effective assessment of medical evidence in legal proceedings and encourage medical professionals to distrust legal regulation. We examine normative criteria a functioning medico-legal notion should presumably meet, e.g. clarity, acce

Time-frequency feature extraction for classification of episodic memory

This paper investigates the extraction of time-frequency (TF) features for classification of electroencephalography (EEG) signals and episodic memory. We propose a model based on the definition of locally stationary processes (LSPs), estimate the model parameters, and derive a mean square error (MSE) optimal Wigner-Ville spectrum (WVS) estimator for the signals. The estimator is compared with stat

Unconventional superconductivity in the nickel chalcogenide superconductor TlNi2Se2

We present the results of a study of the vortex lattice (VL) of the nickel chalcogenide superconductor TlNi2Se2, using small angle neutron scattering. This superconductor has the same crystal symmetry as the iron arsenide materials. Previous work points to it being a two-gap superconductor, with an unknown pairing mechanism. No structural transitions in the vortex lattice are seen in the phase dia