Objective: To assess detailed familial risks for medically diagnosed urolithiasis (UL, urinary tract stone disease) based on nationwide hospital and population records. Patients/Subjects and Methods: Subjects were identified from the Swedish Multigeneration Register in which there were 211 718 patients with UL. Standardised incidence ratios (SIRs) were calculated by comparison to individuals witho

The host employs both cell-autonomous and system-level responses to limit pathogen replication in the initial stages of infection. Previously, we reported that the eukaryotic initiation factor 2α (eIF2α) kinases heme-regulated inhibitor (HRI) and protein kinase R (PKR) control distinct cellular and immune-related activities in response to diverse bacterial pathogens. Specifically for Listeria mono

Föreliggande studie uppmärksammar gärningsmannaskap och offerroller hos tidigare kriminella ungdomar. Hur skildrar ungdomar med kriminell erfarenhet sina egna våldshandlingar/aggressivitet samt erfarenheter av att själva ha blivit utsatta för våld/hot? Ungdomar, som alla har erfarenhet av en kriminell livsstil (med våld, hot, droger och alkohol) och som numera (vid tiden för intervjun) är aktiva i

This paper provides an understanding of changing diversity in Burgazadası within the post-Ottoman, homogenising context of Turkey. It critiques conceptualisations of ‘culture as difference’ within the multiculturalism discourse in Europe and of coexistence as the reduction of differences and identities to pre-existing categories of the Ottoman millet system. Instead, it presents post-Ottoman convi

OBJECTIVE: To examine the predictive capability of a 1-h vs 2-h postload glucose value for cardiovascular morbidity and mortality.DESIGN: Prospective, population-based cohort study (Malmö Preventive Project) with subject inclusion 1974-1992.RESULTS: Median age was 48 (25th-75th percentile: 48-49) years and mean FBG 4.6 ± 0.6 mmol/L. FBG and 2-h postload BG did not independently predict cardiovascu

Plastics are versatile materials with environmental, technical, economical and societal benefits, however plastics also contribute negatively to the environment and climate. Put in numbers around 4% of the fossil oil and gas is used as feedstock for plastics while another 4% is used for providing energy for the manufacturing of plastics. Many initiatives on reducing the negative effects of plastic

The development of a high precision five rotation axes polarimeter using transmission multilayers as polarizers and reflection multilayers as analyzers is presented. In order to cover a wide energy range from EUV to soft X-ray, a set of Mo/Si, Cr/C, Sc/Cr, and W/B4C multilayers for transmission and reflection have been designed and fabricated. A hexapod support allows to align the polarimeter easi

BACKGROUND: With the scale-up of antiretroviral therapy (ART), monitoring programme performance is needed to maximize ART efficacy and limit HIV drug resistance (HIVDR).METHODS: We implemented a WHO HIVDR prospective survey protocol at three treatment centers between 2012 and 2013. Data were abstracted from patient records at ART start (T1) and after 12 months (T2). Genotyping was performed in the

Background: Lung T1 is a potential translational biomarker of lung disease. The precision and repeatability of variable flip angle (VFA) T1 mapping using modern 3D ultrashort echo time (UTE) imaging of the whole lung needs to be established before it can be used to assess response to disease and therapy. Purpose: To evaluate the feasibility of regional lung T1 quantification with VFA 3D-UTE and to

After an initial clarification of the notion of the risk, a brief discussion of the distinction between testing and screening, and of the difficulties of defining genetic information in a precise way follows an overview of public concerns raised by genetic testing and screening. Next section reviews various types of ethical issues in this context. The challenges are not the same for all types and

Objectives. The aim of this study was to assess the incidence, the prenatal detection rate by ultrasound, and the pregnancy outcome of spina bifida (SB) in Denmark (DK) in 2008-2015 and to compare results to national data from Sweden. Methods. Data were retrieved from the Danish Fetal Medicine Database, which includes International Classification of Diseases-(ICD-) 10 codes for pre-or postnatally

Decomposition of soil organic matter (SOM) in permafrost terrain and the production of greenhouse gases is a key factor for understanding climate change-carbon feedbacks. Previous studies have shown that SOM decomposition is mostly controlled by soil temperature, soil moisture, and carbon-nitrogen ratio (C:N). However, focus has generally been on site-specific processes and little is known about v

English (French summary below)Is it still possible to speak of authority other than in negative terms? In particular, to speak of exercising authority in religious institutions? I believe so. It is essential to exercise authority, also in religious institutions. But this exercise is not a simple matter. I propose to reflect on the question from four perspectives. The first is inspired by Martin Lu

Using South African Families (SAF), a new database of settler genealogies, we provide the first comprehensive analysis of women’s fertility in settler South Africa between 1700 and 1900. Differences in parity rates acrossgeographic regions suggest couples knew how to limit fertility prior to theglobal onset of the first fertility transition. We date the start of South Africa’s fertility transition

This study investigates a biodegradable Mg–5Zn–0.3Ca alloy (ZX50) during HPT-processing and long-term heat treatments, the latter with respect to the evolution of intermetallic precipitates and vacancy clusters. Both the precipitates as well as the vacancy clusters achieve strength increases as the Zn atoms may act as potential trapping sites not only for HPT-induced dislocations but also vacancie

Background: Measurement of person-centred care (PCC) outcomes is underdeveloped owing to the complexity of the concept and lack of conceptual clarity. A framework conceptualizing outpatient PCC in rheumatology nurse-led clinics has therefore been suggested and operationalized into the PCC instrument for outpatient care in rheumatology (PCCoc/rheum). Objective: The aim of the present study was to t