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Protein Complexity via Non-Native States: Binding, Stability, and Structural Studies of Calbindin D9k and HAMLET (Human alpha-lactalbumin Made LEthal to Tumor cells).

Popular Abstract in Swedish Kalcium är inblandat i många viktiga processer i kroppen. Kalciumbindande proteiner är viktiga i detta sammanhang. Det finns ofta en vattenmolekyl med på bindningsstället i proteinet och vi har studerat hur den påverkar bindningsegenskaperna. Kalcium är inblandat i många viktiga processer i kroppen. Kalciumbindande proteiner är viktiga i detta sammanhang. Jag har studeUsing optical spectroscopy, nuclear magnetic resonance (NMR), and differential scanning Calorimetry (DSC), I have studied two different calcium binding proteins that can form kinetically trapped altered states. Calcium is very important in numerous biological processes such as blood coagulation, signal transduction, muscle contraction and bone formation. Calcium binding to proteins regulates these

Genetically Engineered Plants: Improved stress tolerance, growth and facilitated protein purification

Heterologous genes were expressed in plants in which the overall goal was to increase the value of the final crop. Various aspects were explored and evaluated, such as improving the stress tolerance, enhancing the availability of oxygen in growing cells and producing rare proteins with increased degrees of purity. In Nature several protective mechanisms against environmental stress have evolved. W

Psychoacoustics and hallucinating schizophrenics. A psychobiological approach to schizophrenia

Popular Abstract in Swedish Psykoakustik och hallucinerande schizofrena Hallucinationer för hörseln är ett stort problem vid schizofreni. Många har försökt förklara men ingen lyckats. Denna avhandling påvisar avvikelser vid schizofrenisjukdomen vilka kan utgöra grundstenar för framtida förståelse av detta plågsamma symptom. Vad är psykoakustik ? Psykoakustik kan beskrivas som psykofysiska studiePsychoacoustic experiments have been conducted for schizophrenic patients with auditory hallucinations in their case history and for reference subjects. The aim of the thesis has been to assess differences between the two groups of subjects. The experiments consisted of tests on perceptual grouping mechanisms measuring how sound with high and low pitches is separated into perceptual streams (Study

Collaborative Healthcare Innovation in Sweden

Abstract in UndeterminedThe medical technology (medtech) industry in Sweden is situated withina complex innovation ecosystem, in which various stakeholders from the public,private and academic sectors need to collaborate to meet demands on effective andeffi cient healthcare. Demographics are changing and those in need of healthcare arenot only larger in numbers than ever but they are also more kno

Level of Confidence Evaluation and Its Usage for Roll-back Recovery with Checkpointing Optimization

Increasing soft error rates for semiconductor devices manu- factured in later technologies enforces the use of fault tolerant techniques such as Roll-back Recovery with Checkpointing (RRC). However, RRC introduces time overhead that increases the completion (execution) time. For non-real-time systems, research have focused on optimizing RRC and shown that it is possible to find the optimal number

Out of the National Closet: Show Me Love

This article deals with the question of heteronormativity, or more precisely, how heteronormativity pertains to the reception of the Swedish film by Lukas Moodysson, Show Me Love (Fucking Åmål).

Biological Phosphorus and Nitrogen Removal in a Single Sludge System

This thesis presents studies on biological phosphorus and nitrogen removal in a single sludge system. The primary aim was to investigate the process stability of a single sludge activated sludge system designed for the combined operation of enhanced biological phosphorus (EBPR) and nitrogen removal. A pilot plant at the Sjölunda wastewater treatment plant in Malmö, Sweden, has formed the basis for

Kan riskbedömare och riskhanterare leva åtskilda?

I det här kapitlet tar vi upp två vetenskapsteoretiska problem med att skilja mellan riskbedömning och riskhantering som har med ”externt” inflytande att göra. Den ena formen av inflytande begränsar våra möjligheter att genomföra en forskningsuppgift. Den andra formen har med utgångspunkten eller frågeställningen för vår forskning att skaffa. Även i de fall där vetenskapen drivs helt av forskarens

A clinical positron emission tomography facility : 2-¹⁸FDG studies : development and results

Popular Abstract in Swedish Fysiologiska och biokemiska processer i den levande kroppen kan studeras mha spårämnestekniken positronemissions tomografi (PET). Den bildgivande tekniken PET kräver radionuklider som sönderfaller genom att sända ut en positron. Positronen är antimateria till elektronen. När positronen har en mycket låg rörelseenergi och träffar på en elektron, ombildas deras vilomassorPositron emission tomography (PET) is a tracer technique used for quantitative in vivo studies of physiological and biochemical processes. Because of the use of positron-emitting radionuclides such as 11-C, 13-N, 15-O and 18-F, which are isotopes of the biologically ubiquitous elements, it is possible to label radiopharmaceuticals which trace biochemical processes precisely. In order to be able to