Search results

Filter

Filetype

Your search for "*" yielded 530849 hits

Are antimicrobial defences in bird eggs related to climatic conditions associated with risk of trans-shell microbial infection?

Introduction: All bird eggs are exposed to microbes in the environment, which if transmitted to the developing embryo, could cause hatching failure. However, the risk of trans-shell infection varies with environmental conditions and is higher for eggs laid in wetter environments. This might relate to generally higher microbial abundances and diversity in more humid environments, including on the s

The origin and evolution of the odd-Z iron-peak elements Sc, V, Mn, and Co

Context. Elements heavier than Li are produced in the interiors of stars. However, for many elements the exact production sites and the timescales on which they are dispersed into the interstellar medium are unknown. Having a clear picture on the origins of the elements is important for our ability to trace and understand the formation and chemical evolution of the Milky Way and its stellar popula

Model-Based Control of Gasoline Partially Premixed Combustion

Partially Premixed Combustion (PPC) is an internal combustion engine concept that aims to yield low NOx and soot emission levels together with high engine efficiency. PPC belongs to the class of low temperature combustion concepts where the ignition delay is prolonged in order to promote the air-fuel-mixture homogeneity in the combustion chamber at the start of combustion. A more homogeneous combu

District heating in case of power failure

Power failures in combination with harsh weather conditions during recent years have led to an increased focus on a safe energy supply to our society. Many vital functions are dependent on electricity; e.g., lighting, telephony, medical equipment, lifts, alarm systems, payment, pumps for town's water and, perhaps the most critical of all. heating systems. In Sweden. district heating (DH) is the mo

Fluid and Highly Curved Model Membranes on Vertical Nanowire Arrays

Sensing and manipulating living cells using vertical nanowire devices requires a complete understanding of cell behavior on these substrates. Changes in cell function and phenotype are often triggered by events taking place at the plasma membrane, the properties of which are influenced by local curvature. The nanowire topography can therefore be expected to greatly affect the cell membrane, emphas

Impact of IL28B-Related Single Nucleotide Polymorphisms on Liver Transient Elastography in Chronic Hepatitis C Infection

Background and Aims: Recently, several genome-wide association studies have revealed that single nucleotide polymorphisms (SNPs) in proximity to IL28B predict spontaneous clearance of hepatitis C virus (HCV) infection as well as outcome following pegylated interferon and ribavirin therapy among genotype 1 infected patients. Additionally the presence of the otherwise favorable IL28B genetic variant

Goal-setting in Multidisciplinary Team Care for Patients with Rheumatoid Arthritis: An International Multi-centre Evaluation of the Contents Using the International Classification of Functioning, Disability and Health as a Reference

Objective: To make a cross-cultural comparison of the contents of rehabilitation goals of patients admitted for rehabilitation and to compare the contents with the comprehensive International Classification of Functioning, Disability and Health (ICF) Core Set for rheumatoid arthritis, by linking their contents to the ICF. Patients: A random sample of 80 patients with rheumatoid arthritis was retri

The mammalian brain in the electromagnetic fields designed by man with special reference to blood-brain barrier function, neuronal damage and possible physical mechanisms

Life oil earth was formed during billions of years, exposed to, and shaped by the original physical forces such as gravitation, cosmic irradiation, atmospheric electric fields and the terrestrial magnetism. The Schumann resonances at 7.4 Hz are all example of oscillations possibly important for life.(1)) The existing organisms are created to function in harmony with these forces. However, in the l

Identification of the gallium vacancy-oxygen pair defect in GaN

Cation vacancies like V-Ga, V-Al and their complexes with oxygen are predicted to be abundant in III-nitrides and to play an important role in nonradiative recombination. Appearing in triple or double negatively charged states, they are not paramagnetic and have not so far been detected by magnetic resonance even under illumination. In this Brief Report, we demonstrate an efficient way to make cat

A fibre-reinforced poroviscoelastic model accurately describes the biomechanical behaviour of the rat achilles tendon.

Computational models of Achilles tendons can help understanding how healthy tendons are affected by repetitive loading and how the different tissue constituents contribute to the tendon's biomechanical response. However, available models of Achilles tendon are limited in their description of the hierarchical multi-structural composition of the tissue. This study hypothesised that a poroviscoelasti

Use of a novel smart heating sleeping bag to improve wearers’ local thermal comfort in the feet

Previous studies have revealed that wearers had low skin temperatures and cold and pain sensations in the feet, when using sleeping bags under defined comfort and limit temperatures. To improve wearers’ local thermal comfort in the feet, a novel heating sleeping bag (i.e., MARHT) was developed by embedding two heating pads into the traditional sleeping bag (i.e., MARCON) in this region. Seven fema

Excited-State Proton-Transfer Processes of DHICA Resolved: From Sub-Picoseconds to Nanoseconds

Excited-state proton transfer has been hypothesized as a mechanism for UV energy dissipation in eumelanin skin pigments. By using time resolved fluorescence spectroscopy, we show that the previously proposed, but unresolved, excited-state intramolecular proton transfer (ESIPT) of the eumelanin building block 5,6-dihydroxyindole-2-carboxylic acid (DHICA) occurs with a time constant of 300 fs in aqu

Decision-Analytic Models: Current Methodological Challenges

Modelers seeking to help inform decisions about insurance (public or private) coverage of the cost of pharmaceuticals or other health care interventions face various methodological challenges. In this review, which is not meant to be comprehensive, we cover those that in our experience are most vexing. The biggest challenge is getting decision makers to trust the model. This is a major problem bec

Cyclic Nucleotide Phosphodiesterase 3 Signaling Complexes

The superfamily of cyclic nucleotide phosphodiesterases is comprised of 11 gene families. By hydrolyzing cAMP and cGMP, PDEs are major determinants in the regulation of intracellular concentrations of cyclic nucleotides and cyclic nucleotide-dependent signaling pathways. Two PDE3 subfamilies, PDE3A and PDE3B, have been described. PDE3A and PDE3B hydrolyze cAMP and cGMP with high affinity in a mutu