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Synthesis and Applications of III-V Nanowires
Low-dimensional semiconductor materials structures, where nanowires are needle-like one-dimensional examples, have developed into one of the most intensely studied fields of science and technology. The subarea described in this review is compound semiconductor nanowires, with the materials covered limited to III-V materials (like GaAs, InAs, GaP, InP,...) and III-nitride materials (GaN, InGaN, AlG
Dispersion forces in inhomogeneous planarly layered media : A one-dimensional model for effective polarizabilities
Dispersion forces such as van der Waals forces between two microscopic particles, the Casimir-Polder forces between a particle and a macroscopic object, or the Casimir force between two dielectric objects are well studied in vacuum. However, in realistic situations the interacting objects are often embedded in an environmental medium. Such a solvent influences the induced dipole interaction. With
"Vi veta icke ännu vadan vädret vill blåsa" : Några svenska ögonvittnesskildringar från de första reformationsåren
Reinterpretation of fossil reproductive structures Zlivifructus microtriasseris (Normapolles complex, Fagales) from the Czech and Polish Late Cretaceous
Flowers and fruits of Zlivifructus microtriasseris, originally described as Caryanthus microtriasseris from the late Turonian to Santonian of the South Bohemian Basins and the late Coniacian to early Santonian of the North Sudetic Basin, are reinterpreted here. Zlivifructus microtriasseris is represented by small, flat fruits, round in outline with persistent perianths, which are fused basally, fo
The precambrian mafic magmatic record, including large igneous provinces of the kalahari craton and its constituents : A paleogeographic review
The study of Precambrian dyke swarms, sill provinces and large igneous provinces on the Kalahari craton in southern Africa has expanded greatly since the pioneering work initiated almost four decades ago. The main contributors to this progress have been a large number of precise U–Pb crystallization ages of mafic rocks, published in a number of recent papers. This information is compiled here into
Steering innovations towards a green economy : Understanding government intervention
In this paper we analyse institutional conditions facilitating the transition towards a green economy by encouraging investment in the enhancement of natural capital and social equity, focussing especially on government interventions. Presenting a conceptual institutional model how innovation generally occurs, we depict system levels that can be influenced by government interventions to facilitate
Effect of hypothermia on haemostasis and bleeding risk : a narrative review
It must be remembered that clinically important haemostasis occurs in vivo and not in a tube, and that variables such as the number of bleeding events and bleeding volume are more robust measures of bleeding risk than the results of analyses. In this narrative review, we highlight trauma, surgery, and mild induced hypothermia as three clinically important situations in which the effects of hypothe
Current status of clinical proteogenomics in lung cancer
Introduction: Lung cancer is the leading cause of cancer death worldwide. Proteogenomics, a way to integrate genomics, transcriptomics, and proteomics, have emerged as a way to understand molecular causes in cancer tumorigenesis. This understanding will help identify therapeutic targets that are urgently needed to improve individual patient outcomes. Areas covered: To explore underlying molecular
Glycated proteins in infant formula may cause inflammation that could disturb tolerance induction and lead to autoimmune disease
Occupational allergic contact dermatitis caused by 2-butyl-1,2-benzisothiazol-3(2H)-one in a metalworker
Population Pharmacokinetic Modelling of FE 999049, a Recombinant Human Follicle-Stimulating Hormone, in Healthy Women After Single Ascending Doses
OBJECTIVE: The purpose of this analysis was to develop a population pharmacokinetic model for a novel recombinant human follicle-stimulating hormone (FSH) (FE 999049) expressed from a human cell line of foetal retinal origin (PER.C6(®)) developed for controlled ovarian stimulation prior to assisted reproductive technologies.METHODS: Serum FSH levels were measured following a single subcutaneous FE
Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients
BACKGROUND: Vasopressin is widely used for vasopressor support in septic shock patients, but experimental evidence suggests that selective V1A agonists are superior. The initial pharmacodynamic effects, pharmacokinetics, and safety of selepressin, a novel V1A-selective vasopressin analogue, was examined in a phase IIa trial in septic shock patients.METHODS: This was a randomized, double-blind, pla
Different pharmacokinetic and pharmacodynamic properties of recombinant follicle-stimulating hormone (rFSH) derived from a human cell line compared with rFSH from a non-human cell line
Pharmacokinetic and pharmacodynamic properties of a novel recombinant follicle-stimulating hormone (rFSH) preparation (FE 999049), expressed by a human cell line (PER.C6), was compared with an rFSH preparation (follitropin α) expressed by a Chinese hamster ovary (CHO) cell line in healthy pituitary-suppressed women. Following single intravenous administration of 225 IU (Steelman-Pohley assay), the
Baddeleyite formation in zircon by Ca-bearing fluids in silica-saturated systems in nature and experiment : resetting of the U–Pb geochronometer
Intergrowths of baddeleyite have been found in zircon grain interiors from amphibolite- and granulite-facies felsic rocks from southwest Greenland. The zircon grains are either close to or in direct contact with quartz. A series of experiments has been conducted using natural, unaltered zircon grains ± SiO2 in H2O–CaCl2, and H2O–Ca(OH)2 solutions with varying molar proportions of Ca to Si at 900 °
Symptoms and signs of severe citalopram overdose
Towards clinical grating-interferometry mammography
Objectives: Grating-interferometry-based mammography (GIM) might facilitate breast cancer detection, as several research works have demonstrated in a pre-clinical setting, since it is able to provide attenuation, differential phase contrast, and scattering images simultaneously. In order to translate this technique to the clinics, it has to be adapted to cover a large field-of-view within a clinic
Several neuropeptide Y receptors modulate cyclic AMP production in the rat brainstem
Carbon monoxide as a putative messenger molecule in the feline lower oesophageal sphincter of the cat
The distribution of the carbon monoxide (CO) producing enzymes haem oxygenase (HO) type 1 and 2 were studied in the feline lower oesophageal sphincter (LOS), as were HO activity and functional effects of CO. HO-2 immunoreactivity was observed in nerve cell bodies in the submucosal and myenteric plexus, nerve fibres, non-neuronal cells surrounding smooth muscle bundles, and in arterial endothelium,
Ligand binding and functional effects of systematic double D-amino acid residue substituted neuropeptide Y analogs on Y1 and Y2 receptor types
In order to identify the signal epitopes of the neuropeptide Y (NPY) molecule, the conformation of the NPY molecule was pertubated by a systematic double D-amino acid replacement of neighbouring residues. These NPY-analogs were examined for receptor affinity and on biological activity. The rat cerebral cortex and hippocampus were used for binding characteristics on Y1 and Y2 binding sites, respect