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Virulence mechanisms of Moraxella in the pathogenesis of infection.

PURPOSE OF REVIEW: Moraxella catarrhalis is an emerging human-specific pathogen responsible for upper and lower respiratory tract infections. Understanding the events in the complex pathogenesis and underlying mechanisms during M. catarrhalis infection is a key to the development of novel therapeutics and vaccines. RECENT FINDINGS: Several novel findings have been reported on Moraxella pathogenesi

Experiences from treatment-predictive KRAS testing; high mutation frequency in rectal cancers from females and concurrent mutations in the same tumor

BACKGROUND: KRAS mutations represent key alterations in colorectal cancer development and lead to constitutive EGFR signaling. Since EGFR inhibition represents a therapeutic strategy in advanced colorectal cancer, KRAS mutation analysis has quickly been introduced as a treatment-predictive test.METHODS: We used a real-time PCR based method to determine KRAS mutations in 136 colorectal cancers with

Rörande "Hej!!!"

Kommentarer och bakgrund till faksimilutgåva av den lundensiska studentpublikationen "Hej!!!" (1892).

Norms and Space. Understanding Public Space Regulation in the Tourist City

How are public spaces regulated in tourist cities? In this doctoral dissertation I seek to answer this question by exploring the intersections between urban tourism and public space regulation. I argue that public space regulation substantially differs from the tourist to the non-tourist zone. This thesis contradicts the common belief that public space regulation may vary from city to city, but re

Characteristics and outcome of brachial plexus birth palsy in neonates.

Aim: To relate pregnancy characteristics to extent and reversibility of brachial plexus birth palsy (BPBP) in neonates. Methods: Retrospective case-control study: newborns with a registered diagnosis of BPBP (n = 168) 1990-2005 were compared to data from a randomly selected control group (n = 1000). Characteristics were related to the level of injury, reversibility and outcome. Results: Among 51 8