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Impact of thrombus aspiration during ST-Elevation Myocardial Infarction : a six month composite endpoint and risk of stroke analyses of the TASTE trial

BACKGROUND: Routine thrombus aspiration during primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) did not reduce the primary composite endpoint in the "A Randomised Trial of Routine Aspiration ThrOmbecTomy With PCI Versus PCI ALone in Patients With STEMI Undergoing Primary PCI" (TOTAL) trial. We aimed to analyse a similar endpoint in "The Thrombus Aspira

Distinguishing asymptomatic bacteriuria from urinary tract infection in the elderly - the use of urine levels of heparin-binding protein and interleukin-6

Asymptomatic bacteriuria (ABU) is highly prevalent among elderly patients. It can be difficult to distinguish ABU from symptomatic urinary tract infection (UTI) in this population, which leads to unnecessary antibiotic treatment. Urinary heparin-binding protein (U-HBP) and urinary interleukin-6 (U-IL-6) have previously been studied as diagnostic markers for UTI. In this study, biomarkers were meas

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing

According to current models of hematopoiesis, lymphoid-primed multi-potent progenitors (LMPPs) (Lin(-)Sca-1(+)c-Kit(+)CD34(+)Flt3(hi)) and common myeloid progenitors (CMPs) (Lin(-)Sca-1(+)c-Kit(+)CD34(+)CD41(hi)) establish an early branch point for separate lineage-commitment pathways from hematopoietic stem cells, with the notable exception that both pathways are proposed to generate all myeloid

Nutritional strategies for skeletal and cardiovascular health : hard bones, soft arteries, rather than vice versa

The focus of this paper is to explore better strategies for optimising bone strength and reducing risk of fracture, while at the same time decreasing risk of cardiovascular disease. The majority of Americans do not consume the current recommended dietary allowance for calcium, and the lifetime risk of osteoporosis is about 50%. However, traditional mononutrient calcium supplements may not be ideal

Change of ultraviolet light transmittance in growing chicken and quail eyes

The ocular media transmittance (OMT), the amount of light transmitted by the ocular media (the cornea, aqueous humour, lens and vitreous humour) to the retina, determines the sensitivity of vertebrate eyes to short-wavelength light, such as ultraviolet (UV). Earlier, we have measured the OMT of adult birds from a range of species and found that smaller eyes transmitted more UV-light to the retina

Method development in inverse modeling applied to supercritical fluid extraction of lipids

Modeling of the supercritical fluid extraction of solid materials is an important aspect in order to understand and predict the process. A comparison of two empirical models, two semi-empirical models and two mechanistic models is performed using calibration of single experiments. It is concluded that the best fit is obtained using a simple empirical expression. Furthermore, single calibrations di

What Makes Institutional Long-Term Care the Most Appropriate Setting for People With Dementia? Exploring the Influence of Client Characteristics, Decision-Maker Attributes, and Country in 8 European Nations

To explore the extent to which client characteristics, decision-maker attributes, and country influence judgments of institutional long-term care (ILTC) appropriateness for people with dementia. Design, setting, and participants: A total of 161 experts in dementia care from 8 European countries reviewed a series of 14 vignettes representing people with dementia on the cusp of ILTC admission and in

Periodic solitons for the elliptic-elliptic focussing Davey-Stewartson equations

We consider the elliptic-elliptic, focussing Davey-Stewartson equations, which have an explicit bright line soliton solution. The existence of a family of periodic solitons, which have the profile of the line soliton in the longitudinal spatial direction and are periodic in the transverse spatial direction, is established using dynamical systems arguments. We also show that the line soliton is lin

Landscape-scale interactions of spatial and temporal cropland heterogeneity drive biological control of cereal aphids

Agricultural landscapes are characterised by dynamic crop mosaics changing in composition and configuration over space and time. Although semi-natural habitat has been often shown to contribute to pest biological control, the effects of increasing landscape heterogeneity with cropland have been disregarded. Here, we examine how cereal aphids, their enemies and biological control are affected by th

Shear and extensional rheology of commercial thickeners used for dysphagia management

People who suffer from swallowing disorders, commonly referred to as dysphagia, are often restricted to a texture-modified diet. In such a diet, the texture of the fluid is modified mainly by the addition of gum or starch-based thickeners. For optimal modification of the texture, tunable rheological parameters are shear viscosity, yield stress, and elasticity. In this work, the flow properties of

Vibrations in a Built Environment : Prediction and Reduction

Vibrations in a built environment can exceed the requirements for sensitive equipment in a building or can cause annoyance to residents. Hence, there is often a need for reducing such vibrations. The vibrations can originate from ambient sources such as motorway traffic, or from internal sources such as people walking inside the building. Disturbing vibrations can be reduced by reduction measures.

Bo i Ro : Texter från ett tvärvetenskapligt symposium om boende, buller och hälsa. Läkaresällskapets hus i Stockholm, den 20 oktober 2016

Sveriges Regering fattade den 9 april 2015 beslut om en ny förordning medbestämmelser om riktvärden för buller utomhus för spårtrafik, vägar ochflygplatser vid bostadsbyggnader. Förordningen (2015:216) om trafikbullervid bostadsbyggnader träder i kraft den 1 juni 2015. I denna förordning finnsförändrade riktvärden för bullerexponering vid bostader som tillåter betydligtmer buller än tidigare, någo

Concentrations of cortisol, testosterone and glycosylated haemoglobin (HbA1c) among construction workers with 12-h workdays and extended workweeks

OBJECTIVES: Working on large scale construction sites have been shown to have severe health consequences in terms of increased risk of hospitalization and disability retirement compared to construction work in general. The aim of the present study was to investigate whether large scale construction work involving 12-h workdays and extended workweeks leads to insufficient recovery measured as incre

Concreteness, Specificity and Emotional Content in Swedish Nouns : Neurocognitive Studies of Word Meaning

The present thesis investigated Swedish nouns differing in concreteness, specificity and emotional content using linguistic, psycholinguistic and neurolinguistic methods. The focus of Paper I was a semantic analysis of discourse produced by a person with a lesion in visual (left occipital) cortex. The results showed that the lesion site was related to with problems processing concrete nouns relateThe present thesis investigated Swedish nouns differing in concreteness, specificity and emotional content using linguistic, psycholinguistic and neurolinguistic methods. The focus of Paper I was a semantic analysis of discourse produced by a person with a lesion in visual (left occipital) cortex. The results showed that the lesion site was related to with problems processing concrete nouns relate

From Periphery to Center: Synchrotron Radiation at DESY, Part I: 1962—1977

In its fifty-year history, the German national research laboratory DESY (Deutsches Elektronen-Synchrotron, German Electron Synchrotron) has undergone a gradual transformation from a single-mission particle physics laboratory to a multi-mission research center for accelerator physics, particle physics, and photon science. The last is an umbrella term for research using synchrotron radiation and, in