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Rheumatoid factor and anti-CCP do not predict progressive joint damage in patients with early rheumatoid arthritis treated with prednisolone: a randomised study

Objective: To analyse if predictors of radiographic progression differ between patients treated with or without prednisolone in early rheumatoid arthritis (RA). Radiographs of hands and feet were assessed using the modified Sharp/van der Heijde score and radiographic progression was defined as an increase in the total Sharp score above 5.8 (the smallest detectable change). Design: Prospective, ran

Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms

Background. The diagnostic work-up and treatment of patients with neuroendocrine neoplasms (NENs) has undergone major recent advances and new methods are currently introduced into the clinic. An update of the WHO classification has resulted in a new nomenclature dividing NENs into neuroendocrine tumours (NETs) including G1 (Ki67 index 20%, G3. Aim. These Nordic guidelines summarise the Nordic Neu

Experimental verification of reciprocity relations in quantum thermoelectric transport

Fundamental symmetries in thermoelectric quantum transport, beyond Onsagers relations, were predicted two decades ago but have to date not been observed in experiments. Recent works have predicted the symmetries to be sensitive to energy-dependent, inelastic scattering, raising the question whether they exist in practice. Here, we answer this question affirmatively by experimentally verifying the

A 24-Hour Study of the Hypothalamo-Pituitary Axes in Huntington's Disease.

Huntington's disease is an inherited neurodegenerative disorder characterised by motor, cognitive and psychiatric disturbances. Patients exhibit other symptoms including sleep and mood disturbances, muscle atrophy and weight loss which may be linked to hypothalamic pathology and dysfunction of hypothalamo-pituitary axes.

Gene and Protein Expression in Human Gliomas

The human gliomas are the most common primary brain tumours. They are highly aggressive with a rapid fatal progression for the patient. The invasive growth pattern and inherent resistance to radiation and chemotherapy account for a lack of efficient therapies. Several novel therapeutic regimes are being investigated, but they have so far shown limited beneficial effects. The molecular heterogeneit

Reglering av värmesystem i flerbostadshus med individuell värmemätning

Indoor temperatures in multifamily houses are indirectly controlled by the outdoor temperature. The radiator supply temperature is a function of the outdoor temperature. This control principle cannot take into account for disturbances from people, electric appliances, airing, sun, and air leakage due to wind. A control setting with a suitable margin can avoid complaints, but may result in overheat

Treatment of chronic hepatitis B infection: An update of Swedish recommendations

The main goal for treatment of chronic hepatitis B is to prevent complications such as liver cirrhosis or hepatocellular carcinoma. Knowledge from population studies of the long-term risk of chronic HBV infection, as well as the recent introduction of pegylated interferon and additional nucleoside analogues has changed the therapeutic situation. Recently, a Swedish expert panel convened to update

Visual flight control in naturalistic and artificial environments.

Although the visual flight control strategies of flying insects have evolved to cope with the complexity of the natural world, studies investigating this behaviour have typically been performed indoors using simplified two-dimensional artificial visual stimuli. How well do the results from these studies reflect the natural behaviour of flying insects considering the radical differences in contrast

Effects of small-scale habitat fragmentation on predator-prey interactions in a temperate sea grass system

During the last decades, fragmentation has become an important issue in ecological research. Habitat fragmentation operates on spatial scales ranging over several magnitudes from patches to landscapes. We focus on small-scale fragmentation effects relevant to animal foraging decision making that could ultimately generate distribution patterns. In a controlled experimental environment, we tested sm

Benchmarking biological nutrient removal in wastewater treatment plants: influence of mathematical model assumptions.

This paper examines the effect of different model assumptions when describing biological nutrient removal (BNR) by the activated sludge models (ASM) 1, 2d & 3. The performance of a nitrogen removal (WWTP1) and a combined nitrogen and phosphorus removal (WWTP2) benchmark wastewater treatment plant was compared for a series of model assumptions. Three different model approaches describing BNR ar

Prediction of Survival of Metastatic Prostate Cancer Based on Early Serial Measurements of Prostate Specific Antigen and Alkaline Phosphatase

PURPOSE: We determined how serial measurements of prostate specific antigen and alkaline phosphatase can be used to predict survival early in the course of hormone treated metastatic prostate cancer. MATERIALS AND METHODS: The study was based on a prospective randomized trial of 915 patients with metastatic prostate carcinoma designed to compare parenteral estrogen (polyestradiol phosphate) vs tot

Detection and localization of load coils from one-port measurements

Abstract in UndeterminedThis paper deals with detection and localization of load coils in the copper access network. The load coil is a legacy device that must be removed before deploying broadband services on twisted-pair transmission lines. The proposed methods do not require dedicated hardware but utilize the already installed transceivers for one-port measurements of the line input impedance.

Island city formation and urban island studies

Regional, national and global cities are disproportionately located on small islands and archipelagos. The spatial turn' within island and urban geography increasingly privileges abstract notions of space, yet the prevalence of big cities on small islands suggests that sensitivity to place-specific spatial factors is necessary if we are to understand both islands and the urban. Whereas previous st

3-year follow-up of 215 fracture patients from a prospective and consecutive osteoporosis screening program. Fracture patients care!

BACKGROUND AND PURPOSE: Fractures can be prevented if osteoporosis is identified and treated. Starting in 2002, we have been using a screening program in which patients between 50 and 75 years of age with a wrist, shoulder, vertebral, or hip fracture are assessed by DEXA of the hip and spine and if osteoporotic or osteopenic, they are encouraged to see a doctor of their own choice. The patients re

Relocation and residential reasoning in very old age -Housing, health and everyday life

Introduction: Moving in very old age is considered to be a major life event and relocation and access to appropriate housing options is a hot topic in the public debate across Europe. For very old people, the decision-making process and aspects influencing relocation is not well studied. Occupational therapy interventions mainly focus on ageing-in-place solutions when aiming for independence and w