Purpose: To study the feasibility of using transscleral visible/near-infrared spectroscopy (Vis/NIRS) to estimate the content of haemoglobin in choroidal tumour phantoms of ex vivo porcine eyes. Methods: Thirty enucleated porcine eyes were prepared with a tumour phantom made by injecting a suspension of gelatine, titanium dioxide and human blood into the suprachoroidal space. The blood concentrati

Garnet amphibolite metataxites at the Steningekusten Nature Reserve in southwestern Sweden contain tonalitic patches and veins. Whole rock chemistry suggests that the protoliths were mafic igneous rocks with alkaline affinities. Orthopyroxene megacrysts are present in leucosome in parts of these garnet amphibolites but absent in others. Orthopyroxene megacrysts were formed by vapor-absent melting

Background and purpose - Prosthetic joint infection (PJI) is a leading cause of early revision after total knee arthroplasty (TKA). Open debridement with exchange of tibial insert allows treatment of infection with retention of fixed components. We investigated the success rate of this procedure in the treatment of knee PJIs in a nationwide material, and determined whether the results were affecte

Dipeptidyl peptidase 4 (DPP-4) was recently found to be expressed in human and mouse islets with different expression patterns. However, whether species-dependent expression pattern is a generalized phenomenon and whether islet DPP-4 activity is regulated are not known. This study was conducted to investigate DPP-4 localization in several different species, and to examine the impact of glucose, in

Objective Recent scientific findings have reinvigorated interest in examining the role of gamma-aminobutyric acid (GABA), the major inhibitory central nervous system neurotransmitter, in chronic pain conditions. Decreased inhibitory neurotransmission is a proposed mechanism in the pathophysiology of chronic pain syndromes such as fibromyalgia (FM). The purpose of this study was to test the hypothe

Phytic acid (IP6) and myo-inositol phosphate esters (IP1-5), including IP5 isomers prepared chemically and enzymatically with bacterial and fungal phytases, were examined for their effects on protein aggregation of soy protein and beta-casein, interaction with Fe3+, and pepsin activity. The results indicated that the aggregating capabilities of IP esters (IP1-6) on the 2 proteins decreased dramati

The existence and effect of different rare earth (R2+/3+/IV) ions in SrAl2O4:Eu2+, R3+ and M2MgSi2O7:Eu2+, R3+ (M: Sr, Ba) persistent luminescence materials was studied with XANES (x-ray absorption near edge structure) measurements at HASYLAB/DESY (Hamburg, Germany) and MAX-lab (Lund, Sweden). The experiments were carried out at 298K for selected rare earth (co-) dopants (Eu2+; Ce3+, Nd3+, Sm3+, D

Obesity is a disorder that develops from the interaction between genotype and environment involving social, behavioral, cultural, and physiological factors. Obesity increases the risk for type 2 diabetes mellitus, hypertension, cardiovascular disease, cancer, musculoskeletal disorders, chronic kidney and pulmonary disease. Although obesity is clearly associated with an increased prevalence of hype

Background: The slopes of the eastern Andes harbour some of the highest biodiversity on Earth and a high proportion of endemic species. However, there have been only a few and limited descriptions of carbon budgets in tropical montane forest regions. Aims: We present the first comprehensive data on the production, allocation and cycling of carbon for two high elevation (ca. 3000 m) tropical montan

Background: Cyclophosphamide induction regimens for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis are effective in 70 to 90% of patients, but they are associated with high rates of death and adverse events. Treatment with rituximab has led to remission rates of 80 to 90% among patients with refractory ANCA-associated vasculitis and may be safer than cyclophosphamide regimens. Me

We consider the problem of computing all-pairs shortest paths in a directed graph with non-negative real weights assigned to vertices. For an n x n 0 - 1 matrix C, let K-C be the complete weighted graph on the rows of C where the weight of an edge between two rows is equal to their Hamming distance. Let MWT(C) be the weight of a minimum weight spanning tree of K-C. We show that the all-pairs short

The androgen receptor (AR) is a key regulator of prostate tumorgenesis through actions that are not fully understood. We identified the repressor element (RE)-1 silencing transcription factor (REST) as a mediator of AR actions on gene repression. Chromatin immunoprecipitation showed that AR binds chromatin regions containing well-characterized cis-elements known to mediate REST transcriptional rep

Caldicellulosiruptor saccharolyticus displays superior H(2) yields on a wide range of carbon sources provided that lactate formation is avoided. Nevertheless, a low lactate flux is initiated as the growth rate declined in the transition to the stationary phase, which coincides with a drastic decrease in the glucose consumption and acetate production fluxes. In addition, the decrease in growth rate

We present data from cathodoluminescence (CL) studies of nanowires (NWs) grown from size-selected gold particles using metal-organic chemical vapour deposition. The NWs in this study all have a GaAs core and are surrounded by a shell of either AlGaAs or GaInP. The spatially and spectrally resolved CL studies were performed in a scanning electron microscope, in a temperature range of 4–300 K. The N

Several treatment alternatives for food waste can result in both energy and nutrient recovery, and thereby potential environmental benefits. However, according to the European Union waste management hierarchy, waste prevention should be the prioritized strategy to decrease the environmental burdens from all solid waste management. The aim of the present study was therefore to investigate the poten

Partial migration, where populations are composed of both migratory and resident individuals, is extremely widespread across the animal kingdom. Researchers studying fish movements have long recognized that many fishes are partial migrants, however, no detailed taxonomic review has ever been published. In addition, previous work and synthesis has been hampered by a varied lexicon associated with t

To determine benefits and harms of arthroscopic knee surgery involving partial meniscectomy, debridement, or both for middle aged or older patients with knee pain and degenerative knee disease.