Popular Abstract in Swedish Städer har kommit att framstå som alltmer drivande i arbetet med att ställa om till ett ekologiskt hållbart samhälle. Utöver att genomföra statliga direktiv eller fokusera på klassiskt kommunala uppgifter som fysisk planering eller renhållning, har kommunala politiker och tjänstemän alltmer kommit att driva en egen miljöpolitik på lokal nivå. Ett exempel är energi- och Local governments are increasingly taking the initiative in environmental governance. But can they make any difference in addressing current environmental challenges, which are becoming more and more global in scope? This PhD thesis explores and analyses the outcomes of proactive initiatives in the field of building energy efficiency, and the governance approaches taken. It addresses outcomes both

Background: Subarachnoid hemorrhage (SAH) is associated with high morbidity and mortality. It is suggested that the associated inflammation is mediated through activation of the mitogen-activated protein kinase (MAPK) pathway which plays a crucial role in the pathogenesis of delayed cerebral ischemia after SAH. The aim of this study was first to investigate the timecourse of altered expression of

BMR (Basal metabolic rate) is an important trait in animal life history as it represents a significant part of animal energy budgets. BMR has also been shown to be positively related to sustainable work rate and maximal thermoregulatory capacity. To this date, most of the studies have focused on the causes of interspecific and intraspecific variation in BMR, and fairly little is known about the fi

Approximately 10—20 % of patients with acute pancreatitis (AP) develop a severe disease with high mortality and morbidity. Activation of pancreatic proteases, the inflammatory response and impaired pancreatic circulation are pathophysiological events that are important in order for the disease to develop. There is no specific treatment for severe AP, and no useful marker for predicting the severit

The function of the efflux pump P-glycoprotein (Pgp) and ABCB1 single nucleotide polymorphisms (SNPs) should be considered as important tools to deepen knowledge of drug nephrotoxicity and disposition mechanisms. The aim of this study is to investigate the association of C3435T, G2677T, C1236T, and T129C ABCB1 SNPs with Pgp activity and exposure to different immunosuppressive drugs in renal transp

Agricultural intensification is recognised as a major driver of biodiversity loss in human-modified landscapes. Several agro-environmental measures at different spatial scales have been suggested to mitigate the negative impact of intensification on biodiversity and ecosystem services. The effect of these measures on the functional structure of service-providing communities remains, however, large

This study investigates online material published in reaction to a Science magazine report showing the absence of peer-review and editorial processes in a set of fee-charging open access journals in Biology. Quantitative and qualitative textual analyses are combined to map conceptual relations in these reactions; and to explore how understandings of scholarly communication and publishing relate to

Use of computational fluid dynamics (CFD) software packages within fire performance based engineering and risk assessment is increasing substantially. An important part in the process is validation and verification in order to be able to assess the accuracy and reliability of the computational tools. To improve the credibility of using CFD modeling in several high-consequence fields, such as the n

Mental health disorders are a rapidly growing public health problem. Despite the fact that lack of trust in the health-care system is considered to be an important determinant of health, there is scarcity of empirical evidence demonstrating its associations with health outcomes. This is the first study which aims to evaluate the association between trust in the health-care system and psychological

Differential cross sections for elastic scattering of photons from the deuteron have recently been measured at the Tagged-Photon Facility at the MAX IV Laboratory in Lund, Sweden. These first new measurements in more than a decade further constrain the isoscalar electromagnetic polarizabilities of the nucleon and provide the first-ever results above 100 MeV, where the sensitivity to the polarizabi

Background: Recent reviews conclude an association between traffic-related pollution and incidence of asthma in children, but not all studies agree. Studies have almost exclusively relied on parental-reported symptoms or parental-reported diagnoses of asthma and wheeze. Our aim was to investigate if traffic exposure is associated with higher incidence of early onset asthma, using registry-based ou

Cellulase and beta-glucosidase production on steam pretreated spruce (SPS) with Trichoderma reesei Rut C30, Trichoderma atroviride TUB F-1505 and TUB F-1663 was investigated. The enzymes were compared in term of activity, temperature optima and hydrolytic capacity. The T. atroviride cellulases proved to have lower temperature optima for filter paper activity (FPA) assay (50 degrees C) and for hydr

Quality requirements play a critical role in driving architectural design and are an important issue in software development. Therefore, quality requirements need to be considered, specified, and quantified early during system analysis and not later in the development phase in an ad-hoc fashion. This paper presents the quality performance model that estimates quality targets in relation to market

Background: Total hip joint replacement (THR) is a high volume, effective intervention for hip osteoarthritis (OA). However, indications and determinants of outcome remain unclear. The 'EUROHIP consortium' has undertaken a cohort study to investigate these questions. This paper describes the variations in disease severity in this cohort and the relationships between clinical and radiographic sever

Photosynthesis is the process by which energy of light is converted into chemical energy by plants, algae and photosynthetic bacteria. For this, highly specialized pigment-proteins have evolved that capture the light and transform the short-lived excited states of pigment molecules into a stable transmembrane potential. By close scrutiny of organization and processes of the photosynthetic pigment

Popular Abstract in Swedish HIV är en av de dödligaste farsoterna i världen och 30-40 miljoner människor beräknas ha dött AIDS. Genom att konstant förändra sig ligger viruset hela tiden ett steg före immunförsvaret, och immunförsvaret klarar därför inte av att bekämpa infektionen. HIV skiljer sig också från andra virus genom att det drabbar och långsamt utplånar immunförsvaret. Det gör att HIV kanThe two genetically related human lentiviruses known today, HIV-1 (which is pandemic) and HIV-2 (which mainly is confined to West Africa), are the causative agents of AIDS. Progressive immune dysfunction and AIDS develop in most cases of untreated HIV-1 infection, but only in approximately 25-30% of HIV-2 infected individuals. The V1-V3 region of the HIV-1 env gp120 is important for HIV-1 corecept