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von Willebrand factor (VWF), a multimeric protein with a central role in hemostasis, has been shown to interact with complement components. However, results are contrasting and inconclusive. By studying 20 patients with congenital thrombotic thrombocytopenic purpura (cTTP) who cannot cleave VWF multimers because of genetic ADAMTS13 deficiency, we investigated the mechanism through which VWF modula

INTRODUCTION AND OBJECTIVE: Several prediction models for falls/near falls in Parkinson's disease (PD) have been proposed. However, longitudinal predictors of frequency of falls/near falls are poorly investigated. Therefore, we aimed to identify short- and long-term predictors of the number of falls/near falls in PD.METHODS: A prospective cohort of 58 persons with PD was assessed at baseline (mean

Previous research indicates that exporting firms are willing to pay a premium to poach workers from other exporting firms if experience working for an internationally engaged firm reduces trade costs. Since international experience is less valuable to non-exporters, we would expect to see differences in recruitments between firms that are internationally engaged and those that serve only their dom

Austria, Finland and Sweden became members of the EU in 1995. This paper examines how support for the euro and trust in the European Central Bank (ECB) have evolved in these three countries since their introduction at the turn of the century. Support for the euro in the two euro-area members Austria and Finland has remained high and relatively stable since the physical introduction of the new curr

We revisit and substantially extend the evidence on the importance of instruction time for student achievement on international assessments. We first successfully replicate the estimate of a positive effect of weekly instruction time in the seminal paper by Lavy (Economic Journal, 125, F397-F424) in a narrow sense. We then extend the analysis to data from other international student assessments an

Boken är en dubbelvolym och innehåller en grekisk text (baserad på cod. Parisinus graecus 2474) utgiven av Britt Dahlman och en svensk översättning av den systematiska samlingen av Apophthegmata Patrum (Ökenfädernas tänkespråk), böckerna 16 och 17. Översättningen har gjorts gemensamt av deltagarna i översättningsseminariet vid Johannesakademin i Linköping under ledning av Britt Dahlman och Per Rön

I tider av ökad e-handel och externhandel kan en plats som vill attrahera besökare i gränslandet mellan turism och handel inte enbart förlita sig på mätbara kvaliteter som utbud och tillgänglighet. Det gäller istället att göra platsen lite roligare, intressantare, mer unik och rikare på upplevelser.

Community Resource Management Areas (CREMAs) in Ghana combine conservation and development objectives and were introduced in the year 2000. In some cases, they have connected collectors of shea (Vitellaria paradoxa) nuts with certified organic world markets, which can be understood as a ‘market-based’ approach to conservation. This paper examines how the benefits of this approach are distributed a

Heat generation in CFRP (carbon fibre reinforced plastic) with electromagnetic induction can result in several benefits to manufacturing and production. However, during induction heating of anisotropic materials such as CFRP, the temperature distribution depends on electrical and thermal conductivity in different directions. This article presents a numerical model for computing the temperature dis

BACKGROUND: Our aim is to study if mammographic density (MD) prior to neoadjuvant chemotherapy is a predictive factor in accomplishing a pathological complete response (pCR) in neoadjuvant-treated breast cancer patients.METHODS: Data on all neoadjuvant treated breast cancer patients in Southern Sweden (2005-2016) were retrospectively identified, with patient and tumor characteristics retrieved fro

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In response to social fragmentation and segregation, public space is increasingly conceived of as an instrument for fostering openness towards differences. Drawing on two recent public spaces—Superkilen in Copenhagen, Denmark, and Jubileumsparken in Gothenburg, Sweden—this article explores the ethical potential of two different design approaches to the sharing of public space—designing for an ethi

Background: Patients with cyanotic congenital heart disease (CCHD) may have a low burden of atherosclerosis. Endothelial dysfunction is an early stage of atherosclerosis and endothelial function is previously studied in smaller CCHD groups with different techniques and variable results. We aimed to examine endothelial function and carotid atherosclerosis in a larger group of CCHD patients. Methods

Modes of climate variability affect global and regional climates on different spatio-temporal scales, and they have important impacts on human activities and ecosystems. As these modes are a useful tool for simplifying the understanding of the climate system, it is crucial that we gain improved knowledge of their long-term past evolution and interactions over time to contextualise their present an

Male-only parental care, while rare in most animals, is a widespread strategy within teleost fish. The costs and benefits to males of acting as sole carer are highly variable among fish species making it challenging to determine the selective pressures driving the evolution of male-only care to such a high prevalence. We conducted a phylogenetic meta-analysis to examine the costs and benefits of p

We apply a spectrally-resolved electron interferometry technique to the measurement of the spectral phase in the vicinity of the 3s13p64p Fano resonance of argon. We show that it allows disentangling the phases of the two nearly-overlapping electron wavepackets corresponding to different spin-orbit final states. Using simple assumptions, it is possible to process the experimental data and numerica

We study the permeability and selectivity ('permselectivity') of model membranes made of polydisperse polymer networks for molecular penetrant transport, using coarse-grained, implicit-solvent computer simulations. In our work, permeability P is determined on the linear-response level using the solution-diffusion model, P = KDin, i.e., by calculating the equilibrium penetrant partition ratio K and

BACKGROUND: Engagement in activities meaningful to the individual may support the process of recovery in those with mental illness. Persons with psychiatric disabilities may reduce their engagement in meaningful activities to various degrees with possible fluctuations over time. We hypothesized that activity engagement can be altered when opportunities and support are offered at an individual and