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Prompt gamma tomography during BNCT – a feasibility study

The success of clinical boron neutron capture therapy (BNCT) lies in the ability to manage the radiobiological effect on the tumour and healthy tissue, and thus, accurate dosimetry measurements is pertinent for each individual patient. In the present work we investigate the possibility of performing online prompt gamma tomography (PGT) during BNCT. A prototype detector system was constructed, whic

Flexible lock-in detection system based on synchronized computer plug-in boards applied in sensitive gas spectroscopy

We present a flexible and compact, digital, lock-in detection system and its use in high-resolution tunable diode laser spectroscopy. The system involves coherent sampling, and is based on the synchronization of two data acquisition cards running on a single standard computer. A software-controlled arbitrary waveform generator is used for laser modulation, and a four-channel analog/digital board r

Reflection phase of scattering electrons in a single-channel atomic wire

A theoretical study of the phase property of the reflection coefficient of a single-channel quantum system is presented. This reflection phase information is required for a complete characterization of the scattering problem in the system. It is found that the phase of the reflection coefficient of the system shifts abruptly by pi when the reflection probability passes through a zero. It is also f

Plastoquinone redox control of chloroplast thylakoid protein phosphorylation and distribution of excitation energy between photosystems: discovery, background, implications

Chloroplast thylakoid protein phosphorylation was discovered, and the most conspicuous phosphoproteins identified, by John Bennett at Warwick University. His initial findings were published in 1977. The phosphoproteins included apoproteins of chloroplast light harvesting complex II. Thylakoid protein phosphorylation was shown to influence distribution of excitation energy between Photosystems I an

The endocannabinoid system promotes astroglial differentiation by acting on neural progenitor cells

Endocannabinoids exert an important neuromodulatory role via presynaptic cannabinoid CB1 receptors and may also participate in the control of neural cell death and survival. The function of the endocannabinoid system has been extensively studied in differentiated neurons, but its potential role in neural progenitor cells remains to be elucidated. Here we show that the CB1 receptor and the endocann

Footwear for cold work: a field study about work on high masts

A series of field studies at cold workplaces were initiated. This paper deals with the study at a telecommunication company and the main attention is paid to the thermal responses of the feet and footwear performance. The study was carried out in February. Eight male workers were the subjects. They were selected among volunteers who carried out various jobs on high masts on four different days. Th

Säkerhet vid betongarbete : utveckling av bärförmåga hos armerade betongkonstruktioner i tidig ålder

Detta arbete behandlar tillväxten hos enkelarmerade betongkonstruktioners bärförmåga, speciellt under vinter fram till formgivning. Arbetet är uppdelat i 3 delar. I den första studeras betongens hållfasthetstillväxt vid olika härdningstemperaturer. I den andra delen bestäms brottlasten hos 30 betongbalkar och 6 betongväggar. I den tredje delen beräknas temperaturutvecklingen hos betongbalkar.

Chromosome ends in Chironomus pallidivittatus contain different subfamilies of telomere-associated repeats

Tandemly repeated 340 bp sequences, TA repeats, are present in seven of the eight pairs of chromosome ends in Chironomus pallidivittatus, being absent from the telocentric left end of chromosome four. We have previously shown that the family of TA repeats consists of four main subfamilies. One subfamily is composed of a master unit and the other three contain derived units, each of which has a sma

Very low-density lipoprotein activates nuclear factor-kappaB in endothelial cells

High plasma levels of VLDL are associated with increased risk for atherosclerosis. Here we show that VLDL (75 to 150 microg/mL) activates nuclear factor-kappaB (NF-kappaB), a transcription factor known to play a key role in regulation of inflammation. Oxidation of VLDL reduced its capacity to activate NF-kappaB in vitro, whereas free fatty acids such as linoleic and oleic acid activated NF-kappaB

Decreased inducibility of TNF expression in lipid-loaded macrophages.

BACKGROUND: Inflammation and immune responses are considered to be very important in the pathogenesis of atherosclerosis. Lipid accumulation in macrophages of the arterial intima is a characteristic feature of atherosclerosis which can influence the inflammatory potential of macrophages. We studied the effects of lipid loading on the regulation of TNF expression in human monocyte-derived macrophag

Effects of phosphorothioated neuropeptide Y Y1-receptor antisense oligodeoxynucleotide in conscious rats and in human vessels

1. Metabolically stabilized (phosphorothioate) human and rat NPY Y1 receptor oligodeoxynucleotides (ODNs) complimentary to the rat or human Y1 mRNA were synthesized; [sense (rY1-SODN, 5'-AATTCAACTCTGTTCTCC-3'), antisense (hY1-ASODN, 5'-CCTGGGAAAATAATGTTG-3' and rY1-ASODN, 5'-GGAGAACAGAGTTGAATT-3') and mismatches (hY1-MMODN, 5'-CCTGAGATAA-TAAGGTTG-3' and rY1-MM 5'-GTAGATCAGAGATGAAGT-3')] and used t