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Long-term regulation of cyclic nucleotide phosphodiesterase type 3B and 4 in 3T3-L1 adipocytes.

Phosphodiesterase 3B (PDE3B), is known to play an important role in acute insulin and cAMP-mediated regulation of lipid metabolism, and PDE4 are the main PDE types expressed in adipocytes. Here, we show that members of all PDE4 isoforms are expressed in 3T3-L1 and primary mouse adipocytes. Long-term treatment of 3T3-L1 adipocytes with insulin induced up-regulation of PDE3B and PDE4D in a phosphati

Anatomy and biomechanics of the back muscles in the lumbar spine with reference to biomechanical modeling

Study Design. This article describes the development of a musculoskeletal model of the human lumbar spine with focus on back muscles. It includes data from literature in a structured form. Objective. To review the anatomy and biomechanics of the back muscles related to the lumbar spine with relevance for biomechanical modeling. Summary of Background Data. To reduce complexity, muscle units have be

Människor i utmark

Popular Abstract in Swedish Målsättningen med föreliggande studie är att belysa det komplexa och varierade bruket av skogliga utmarker under järnålder, medeltid och tidig modern tid. Fysiska lämningar från landskapet Värmland i västra Sverige undersöks, med särskilt fokus på lokalsamhällena Dalby och Gunnarskog. De fysiska lämningarna i fokus för denna studie är främst fångstgropar för älg, lågtekThe aim of this study is to illuminate the complex and varied uses of the forested outlands, from the Iron Age, through the Middle Ages, to Early Modern times. Material evidence from the landscape of Värmland, in Western Sweden, will be examined, focusing on the local societies of Dalby and Gunnarskog. Evidence for the reconstruction of outland activities comes from a range of sites, including pit

Evaluation of malignancy in ring enhancing brain lesions on CT by thallium-201 SPECT

OBJECTIVE: To investigate patients with cystic enhancing lesions on CT and to determine whether thallium-201 (201Tl) SPECT adds to further preoperative information in differential diagnosis between gliomas and abscesses. METHODS: Twenty one patients with cystic ring enhancing CT findings were studied and uptake indices were compared with CT enhancement volumes, histopathology, and survival times.

Interpersonell kommunikation : en studie av elever med hörselnedsättning i särskolan

Popular Abstract in Swedish Denna studie handlar om interpersonell kommunikation mellan barn och vuxna i särskolan. Specifikt inriktas den på att studera den kommunikation som sker när de kommunikationssätt som parterna använder är teckenspråk och tecken och samtidigt tal. I fokus är elever med hörselnedsättning och utvecklingsstörning, vilken är en liten, unik och outforskad elevgrupp, men också Pupils with impaired hearing and moderate to severe learning difficulties usually go to special schools for the severely learning disabled. Few studies have been conducted on the interpersonal communication among these pupils. The all-embracing aim of this study is to look closer into the communication that takes place during the school day between children and adults, in cases where Sign Language

Prediction of death in patients with primary intracerebral hemorrhage: a prospective study of a defined population.

OBJECT: Predictors of early (30-day) and long-term (1-year) mortality rates after primary intracerebral hemorrhage (ICH) were studied in a large population in southern Sweden. METHODS: All cases of primary ICH, verified using computerized tomography (CT) scanning or autopsy study, were prospectively registered at the 12 hospitals covering a defined population of 1.14 million during the calendar ye

Experimental studies of attosecond pulse trains

We present experimental measurements of attosecond pulse trains. The characterization of the pulses uses a spectral interferometry technique that is implemented with a Mach-Zehnder interferometer. This allows us to manipulate independently the pump and probe pulses for a wide range of applications. By letting the attosecond pulses pass through metallic films, we can in particular compensate for th

Pluggable checking and inferencing of nonnull types for Java

We have implemented a non-null type checker for Java and a new non-null inferencing algorithm for analyzing legacy code. The tools are modular extensions to the JastAdd extensible Java compiler, illustrating how pluggable type systems can be achieved. The resulting implementation is compact, less than 230 lines of code for the non-null checker and 460 for the inferencer. Non-null checking is a loc

Direct electrochemical oxidation of DNA on polycrystalline gold electrodes

Electrochemical CV and SWV studies were performed with double stranded DNA from salmon testes (dsDNA) and single stranded DNAs, containing 25 nucleotides (ssDNA) directly adsorbed at polycrystalline An electrodes. A distinct oxidation peak at + 730 mV (SWV, scan rate 0.248 V s(-1)) or at + 730 - + 780 mV (CV, scan rate from 0.3 to 1 V s(-1)) was obtained with DNA-modified Au electrodes after a tim

Finite-sample distribution of a recursively mean-adjusted panel data unit root test

In this paper, we investigate the finite-sample distribution of the recursively mean-adjusted panel data unit root test of Shin et al. [Shin, D. W., Kang, S. and Oh, M.-S., 2004, Recursive mean adjustment for panel unit root tests. Economics Letters, 84, 433-439.]. More precisely, we provide response surface parameters that can be used to calculate small-sample critical values for the test. Furthe

Focus on the tumor periphery in MRI evaluation of soft tissue sarcoma: infiltrative growth signifies poor prognosis

Purpose. Infiltrative microscopical peripheral growth of soft tissue sarcomas (STS) has been shown to be of prognostic importance and preoperative risk stratification could individualize neoadjuvant treatment. Patients and methods. We assessed peripheral tumour growth pattern on preoperative MRI from 78 STS. The findings were correlated to histopathology and to outcome. Results. The MRI-based peri

Retention patterns of asbestos fibres in lung tissue among asbestos cement workers

Retention patterns in lung tissue (determined by transmission electron microscopy and energy dispersive spectrometry) of chrysotile, tremolite, and crocidolite fibres were analysed in 69 dead asbestos cement workers and 96 referents. There was an accumulation of tremolite with time of employment. Among workers who died within three years of the end of exposure, the 13 with high tremolite concentra

Fed-batch cultivation of Saccharomyces cerevisiae on lignocellulosic hydrolyzate

Saccharomyces cerevisiae grows very poorly in dilute acid lignocellulosic hydrolyzate during the anaerobic fermentation for fuel ethanol production. However, yeast cells grown aerobically on the hydrolyzate have increased tolerance for the hydrolyzate. Cultivation of yeast on part of the hydrolyzate has therefore the potential of enabling increased ethanol productivity in the fermentation of the h