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There is a need for integrated care and smooth collaboration between care-providing organisations and professions to create a continuum of care for frail older people. However, collaboration between organisations and professions is often problematic. The aim of this study was to examine the process of implementing a new continuum of care model in a complex organisational context, and illuminate so

Background: Earlier studies have shown an association between secondhand tobacco smoke and allergy development in children. Furthermore, there is an increased risk of developing an allergy if the parents have an allergy. However, there are only few studies investigating the potential synergistic effect of secondhand tobacco smoke and allergic heredity on the development of an allergy. Methods: The

Hematopoiesis is the process of blood formation from a limited pool of hematopoietic stem cells (HSCs). These rare stem cells can both self-renew to maintain the HSC pool, and differentiate to continuously replenish lost blood cells. The mechanisms of HSC regulation are not fully known. The aim of this thesis was to study the role of the Hippo signaling pathway in HSCs. The Hippo pathway is a newl

The endoplasmic reticulum (ER) is crucial for protein synthesis and protein maturation, is involved in cell stress and serves in neurons as the major intracellular Ca2+ store. Neuronal ER forms a continuous network of cisterns and tubules extending from soma to a subset of dendritic spines. The continuity of ER structure is important for maintaining ER basic functions and necessary for proteins an

Victimization in cyberspace has emerged as a new public health issue among the young. The main purpose of this study was to analyze associations between cyber victimization defined as cyber harassment (CH) (a somewhat broader concept than cyberbullying) and subjective health complaints (SHC), to study whether these associations were modified by parental/friend support (measured as communication),

Some of the main bottlenecks for the development and commercialization of photovoltaic/thermal hybrids are the lack of an internationally recognized standard testing procedure as well as a method to compare different hybrids with each other and with conventional alternatives. A complete methodology to characterize, simulate and evaluate concentrating photovoltaic/thermal hybrids has been proposed

Ankylosing Spondylitis (AS) is a chronic inflammatory disease with onset in young adults, but little is known about the prevalence in older age groups. Furthermore, there is very limited information of health status of elderly patients with AS. Our objective was to estimate the prevalence of moderate to severe radiographic sacroiliitis in elderly men and its impact on health.