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Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection.

The aim of this study was to evaluate the beta cell and incretin function in patients with HNF4A and HNF1A MODY during a test meal. Clinical characteristics and biochemical data (glucose, proinsulin, insulin, C-peptide, GLP-1 and GIP) during a test meal were compared between MODY patients from eight different families. BMI-matched T2D and healthy subjects were used as two separate control groups.

Differences in fracture pattern between an urban and a rural population: a comparative population-based study in southern Sweden

Differences in the incidence of hip fractures have been reported between urban and rural areas. In this population-based study the characteristics of fracture patterns between the city of Malmo and the nearby rural district of Sjobo were compared. A total of 782 individuals in Malmo and 486 in Sjobo were invited to participate. Fracture history for all invited was registered. The odds ratio for fr

Cost-effectiveness analysis in glaucoma: what drives utility? Results from a pilot study in Sweden

Purpose: To investigate the effect of different levels of visual field defect in glaucoma on utilities and to test if utilities could be assessed using a general questionnaire such as the EQ-5D. Methods: A cross-sectional study in 199 patients with ocular hypertension or open-angle glaucoma grouped into 5 severity stages according to visual field defects was performed in 4 specialized ophthalmic c

Synchrotron Infrared Microspectroscopy at beamline 73 MAX-lab, Lund, Sweden

The infrared beamline at MAX-lab in Lund is equipped with a Bruker Hyperion 3000 microscope combined with an IFS/66v FTIR instrument. In combination with a number of different detectors and objectives this makes it possible to study a large number of different samples. For example there is a FPA detector for mapping larger areas and a Bolometer for measurements in the far infrared. A number of exa