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Background: Dark skin and low exposure to sunlight increase the risk of Vitamin D insufficiency in children. Objective: The aim of the study was to evaluate the amount of Vitamin D needed to ascertain that most children > 4 y of age attain sufficient serum25-hydroxyVitamin D [S-25(OH)D; i.e.,≥50 nmol/L] during winter regardless of latitude and skin color. Design: In a longitudinal, double-blind, r

Aim: Complement-mediated atypical haemolytic uraemic syndrome (aHUS) is a rare disease with high mortality and morbidity if left untreated. The diagnostic work-up is complicated and the manifestations overlap with other conditions. Therefore, we hypothesize that complement-mediated aHUS is an under diagnosed disease. Methods: A cohort of 768 referrals referred to the Coagulation Unit in Malmo, Swe

Background: Although ranibizumab has been used for the treatment of wet age-related macular degeneration (AMD) since 2007, real-world studies still report undertreatment resulting in a less favorable visual outcome. In this study, two different time cohorts of patients treated with ranibizumab for wet AMD in routine care were analyzed to observe whether there was a change over time regarding visua

Background: Child mortality differed greatly within rural regions in Europe before and during the mortality transition. Little is known about the role of nutrition in such geographic differences, and about the factors affecting the nutritional status and hence the disease outcomes.Objective: Focusing on nutrition, we analyse the effects of soil type, used as an indicator of the farm-level agricultBackground: Child mortality differed greatly within rural regions in Europe before and during the mortality transition. Little is known about the role of nutrition in such geographic differences, and about the factors affecting the nutritional status and hence the disease outcomes.Objective: Focusing on nutrition, we analyse the effects of soil type, used as an indicator of the farm-level agricult

Vägen till en ätstörning, som exempelvis anorexia nervosa eller hetsätningsstörning leder alltid förbi ett gränsland där energiintaget stegvis förändras. Kanske stoppar man i sig aningen mindre mat på måndagen än man gjorde på söndagen och på tisdagen lite mindre än på måndagen. Eller kanske man frivilligt stoppar fingrarna i halsen någon gång när man känner att man har ätit för mycket. Detta gränThe path to an eating disorder (ED) always leads through a borderland, which, in this thesis, is referred to as disordered eating (DE) (Neumark-Sztainer, Wall, Eisenberg, Story, & Hannan, 2006; Waaddegaard, Thoning, & Petersson, 2003). In this borderland, people tend to make unhealthy eating choices, such as greatly reducing their food intake, self-inducing vomiting, or engaging in binge e

Background: Prognostic factors in patients with localized primary cutaneous malignant melanoma (CMM) are well described. However, prognostic factors for recurrence are less documented. Objectives: The aim of this study was to identify prognostic risk factors for first recurrence in patients with localized stages I-II CMM using population-based data. Methods: This study included 1437 CMM patients r

In the search for viable pathways for transforming governance and institutions in the Rio+20 agenda,strengthening of public‐private governance networks has been emphasized. Important initiatives arefound in the expanding bioenergy sector where several certification schemes have been launched forensuring that bioenergy feedstock meet environmental and social requirements. These initiatives areencou

The adrenal-derived hormones dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are the most abundant circulating hormones and their levels decline substantially with age. DHEAS is considered an inactive precursor, which is converted into androgens and estrogens via local metabolism in peripheral target tissues. The predictive value of serum DHEAS for fracture risk is unknown. The aim of this s