Several dietary factors have been studied in relation to prostate cancer; however, most studies have not reported on subtypes of fruit and vegetables or tumor characteristics, and results obtained so far are inconclusive. This study aimed to examine the prospective association of total and subtypes of fruit and vegetable intake with the incidence of prostate cancer overall, by grade and stage of d

BACKGROUND: The Pediatric Heart Network designed a clinical trial to compare aortic root growth and other short-term cardiovascular outcomes in children and young adults with Marfan syndrome randomized to receive atenolol or losartan. We report here the characteristics of the screened population and enrolled subjects.METHODS AND RESULTS: Between 2007 and 2011, 21 clinical sites randomized 608 subj

Exposure to exogenous (oral contraceptives, postmenopausal hormone therapy) and endogenous (number of ovulatory cycles, adiposity) steroid hormones is associated with breast cancer risk. Breast cancer risk associated with these exposures could hypothetically be modified by genes in the steroid hormone synthesis, metabolism and signaling pathways. Estrogen receptors are the first step along the pat

Background Increased levels of thyroglobulin (Tg) and thyroid-stimulating hormone (TSH) are associated with differentiated thyroid carcinoma (TC) risk, but strong epidemiological evidence is lacking. Methods Three hundred fifty-seven incident TC case patients (n = 300 women and 57 men; mean age at blood collection = 51.5 years) were identified in the EPIC cohort study and matched with 2 (women) or

Incidence rates of differentiated thyroid carcinoma (TC) have increased in many countries. Adiposity and dietary risk factors may play a role, but little is known on the influence of energy intake and macronutrient composition. The aim of this study is to investigate associations between TC and the intake of energy, macronutrients, glycemic index (GI) and glycemic load in the European Prospective

Metabolomics is now widely used to characterize metabolic phenotypes associated with lifestyle risk factors such as obesity. The objective of the present study was to explore the associations of body mass index (BMI) with 145 metabolites measured in blood samples in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Metabolites were measured in blood from 392 men from t

Approximately 5% to 10% of melanoma may be hereditary in nature, and about 2% of melanoma can be specifically attributed to pathogenic germline mutations in cyclin-dependent kinase inhibitor 2A (CDKN2A). To appropriately identify the small proportion of patients Who benefit most from referral to a genetics specialist for consideration of genetic testing for CDKN2A, We have reviewed available publi

Hepatocellular carcinoma (HCC), the most prevalent form of liver cancer, is difficult to diagnose and has limited treatment options with a low survival rate. Aside from a few key risk factors, such as hepatitis, high alcohol consumption, smoking, obesity, and diabetes, there is incomplete etiologic understanding of the disease and little progress in identification of early risk biomarkers.

Background: Little is known about the causes of thyroid cancer, but insulin-like growth factor-I (IGF-I) might play an important role in its development due to its mitogenic and antiapoptotic properties. Methods: This study prospectively investigated the association between serum IGF-I concentrations and risk of differentiated thyroid carcinoma in a case-control study nested within the European Pr

BACKGROUND: Alcohol is an established risk factor for several cancers, but modest alcohol-cancer associations may be missed due to measurement error in self-reported assessments. Biomarkers of habitual alcohol intake may provide novel insight into the relationship between alcohol and cancer risk.METHODS: Untargeted metabolomics was used to identify metabolites correlated with self-reported habitua

Background: The mechanisms underlying the obesity-cancer relationship are incompletely understood. This study aimed to characterise metabolic signatures of greater body size and to investigate their association with two obesity-related malignancies, endometrial and colorectal cancers, and with weight loss within the context of an intervention study. Methods: Targeted mass spectrometry metabolomics

(1) Background: Methyl-group donors (MGDs), including folate, choline, betaine, and methionine, may influence breast cancer (BC) risk through their role in one-carbon metabolism; (2) Methods: We studied the relationship between dietary intakes of MGDs and BC risk, adopting data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort; (3) Results: 318,686 pre-and postmen

BACKGROUND: Lymphatic disorders such as protein-losing enteropathy, plastic bronchitis, and chylothorax are important complications of the Fontan circulation and ultimately result in an increased risk of early death. Several European centers are now performing lymphatic procedures. The aim of this study is to map the extent of these lymphatic disorders and treatments provided across European pedia

Rapport vecka 36 (publicerad 2020-09-10) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 4 Aktuell status 5 10 postnummerområden med högst andel studiedeltagare med symtom överensstämmande med covid-19 den 7 september . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 10 postnummerområden med lägst andel studiedeltagare med symtom överensstämmande med

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka36_coss.pdf - 2025-07-10

Rapport vecka 41 (publicerad 2020-10-14) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 5 Aktuell status 5 10 postnummerområden med lägst andel studiedeltagare med symtom överensstämmande med covid-19 den 12 oktober . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka41_coss.pdf - 2025-07-10

Rapport vecka 43 (publicerad 2020-10-28) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 5 Aktuell status 5 10 postnummerområden med lägst andel studiedeltagare med symtom överensstämmande med covid-19 den 26 oktober . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka43_coss.pdf - 2025-07-10

Rapport vecka 37 (publicerad 2020-09-16) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 4 Aktuell status 5 10 postnummerområden med högst andel studiedeltagare med symtom överensstämmande med covid-19 den 14 september . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 10 postnummerområden med lägst andel studiedeltagare med symtom överensstämmande med

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka37_coss.pdf - 2025-07-10

Rapport vecka 39 (publicerad 2020-09-30) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 5 Aktuell status 5 10 postnummerområden med högst andel studiedeltagare med symtom överensstämmande med covid-19 den 28 september . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 10 postnummerområden med lägst andel studiedeltagare med symtom överensstämmande med

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka39_coss.pdf - 2025-07-10

Rapport vecka 40 (publicerad 2020-10-07) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 5 Aktuell status 5 10 postnummerområden med lägst andel studiedeltagare med symtom överensstämmande med covid-19 den 5 oktober . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka40_coss.pdf - 2025-07-10

Rapport vecka 42 (publicerad 2020-10-21) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 5 Aktuell status 5 10 postnummerområden med lägst andel studiedeltagare med symtom överensstämmande med covid-19 den 19 oktober . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka42_coss.pdf - 2025-07-10