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Muscarinic acetylcholine receptors (mAChRs) play a central role in the mammalian nervous system. These receptors are G protein-coupled receptors (GPCRs), which are activated by the agonists acetylcholine and muscarine, and blocked by a variety of antagonists. Mammals have five mAChRs (m1-m5). In this study, we cloned two structurally related GPCRs from the fruit fly Drosophila melanogaster, which,
As information technology develops in the past decade, the digital society has affected every aspect of the social structure. The legal system faces the challenge in implementing the legal norms, yet the evolved architecture of technology in the digital society makes it difficult for the law to perform its function. One of the fields of challenge is legal protection of personal data. Legislat
Project coordinator Contact details Email: stefan [dot] olin [at] nateko [dot] lu [dot] se Phone: +46 46 222 38 30Organisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageStefan Olins profile in Lund University research portalOther affiliations Member of Strategic Research Area BECC: Biodiversity and Ecosystem services in a Changing Climate Profile area member LU
https://www.nateko.lu.se/stefan-olin - 2025-12-21
Professor emeritus Contact details Email: ulf [dot] elg [at] fek [dot] lu [dot] seOrganisation Marketing Service point: 10 WebpageUlf Elgs profile in Lund University research portal Publications Displaying of publications. Sorted by year, then title. Filter by type AllBookBook chapterConference - otherConference paperJournal articleReportTeaching caseWorking paper Filter International retailers as
https://www.lusem.lu.se/ulf-elg - 2025-12-21
Popular Abstract in Swedish Shimazaki Toson (1872 - 1943) anses vara Japans främste företrädare för shizenshugi - en japansk form av fransk Naturalisme. Hans debut som romanförfattare skedde 1906 med Hakai - Löftesbrottet. Romanen anses allmänt vara en representant för kokuhaku shosetsu, eller en "bekännelseroman". Denna avhandling påvisar att författaren hade politiska ambitioner att påvisa diskrPublished in 1906, Hakai or The Broken Commandment in English, by Shimazaki Tôson, is generally considered the first novel in the genre of shizenshugi, a Japanese variation of French Naturalisme. Traditionally, the novel has been viewed as an example of kokuhaku shôsetsu, or “confessional novel” in that the protagonist “confesses” his origin as a member of Eta¾an autochtonous and despised minority
Background & Aims Predniso(lo)ne, alone or in combination with azathioprine, is the standard-of-care (SOC) therapy for autoimmune hepatitis (AIH). However, the SOC therapy is poorly tolerated or does not control disease activity in up to 20% of patients. We assessed the efficacy of mycophenolate mofetil (MMF) and tacrolimus as second-line therapy for patients with AIH. Methods We performed a r
Following a brief review of the development of medical ultrasonics from the mid-1930s to the mid-1950s, the collaboration between Edler and Hertz that began in Lund in 1953 is described. Using an industrial ultrasonic flaw detector, they obtained time-varying echoes transcutaneously from within the heart. The first clinical applications of M-mode echocardiography were concerned with the assessment
Popular Abstract in Swedish Jahai är ett språk som tillhör asli-grenen av språkfamiljen mon-khmer och talas av ca 1000 jägare-samlare i bergsregnskogarna i norra Västmalaysia. Denna avhandling, baserad på språkliga data inhämtade i fält, beskriver och analyserar grammatiken i jahai. Arbetet inleds med en introduktion till språket och dess talare och behandlar sedan bl.a. ljudsystemet (fonologin), Jahai, a language belonging to the Aslian branch of the Mon-Khmer language family, is spoken by a group of about 1,000 hunter-gatherers in the montane rainforests of northern Peninsular Malaysia. Drawing on linguistic data collected in the field, the present dissertation is a study of the grammar of Jahai. The work begins with an introduction to Jahai and its speakers, and subsequent chapters char
Goodpasture disease (GP) is defined by the presence of anti-glomerular basement membrane (anti-GBM) antibodies and rapidly progressive glomerulonephritis. Besides anti-GBM, many patients with GP produce anti-neutrophil cytoplasmic antibodies (ANCA). For elucidation of the pathophysiologic significance of ANCA in this setting, epitope and antigen specificity of the anti-GBM antibodies and antigen s
The seventeen papers were originally discussed in joint seminars in Lund and Nanjing in the beginning of 2014, and presented at a conference in Stockholm in October 2014.
English is widely recognized as the language of science, and English-language publications (ELPs) are rapidly increasing. It is often assumed that the number of non-ELPs is decreasing. This assumption contributes to the underuse of non-ELPs in conservation science, practice, and policy, especially at the international level. However, the number of conservation articles published in different langu
Climate warming is expected to accelerate glacier retreat and shift hydrological regime, which poses great threat to regional water resources in terms of amount, variability, and quality. This is especially true in arid regions with glaciers such as the Central Asia. However, few models manage to mimic both glacier runoff and surface changes with adequate performance. To narrow this gap, we integ
BACKGROUND: Endolichenic fungi are microbes that inhabit the thalli of lichens and produce various unique chemicals that can be used for pharmaceutical purposes.PURPOSE: This study screened a library of endolichenic fungal extracts to identify novel anticancer agents capable of suppressing the tumorigenicity of human cancer cells.METHODS: Active compounds were isolated from extracts of endolicheni
