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Moraxella catarrhalis immunoglobulin D (IgD)-binding protein (MID) is an outer membrane protein with specific affinity for soluble and cell-bound human IgD. Here, we demonstrate that mutated M. catarrhalis strains devoid of MID show a 75% decreased activation of human B cells as compared with wild-type bacteria. In contrast to MID-expressing Moraxella, the MID-deficient Moraxella mutants did not b

Breast cancer incidence has markedly increased in Western countries for reasons that are not entirely understood. We characterized periodic and age-specific incidence trends of breast cancer in immigrants who migrated from low incidence areas to Sweden. The incidence in immigrants was compared to that in native Swedes and standardized incidence ratios (SIRs) were calculated, based on the Swedish F

The ADAMs (a disintegrin and metalloprotease) comprise a large family of multidomain proteins with cell-binding and metalloprotease activities. The ADAM12 cysteine-rich domain (rADAM12-cys) supports cell attachment using syndecan-4 as a primary cell surface receptor that subsequently triggers beta(1) integrin-dependent cell spreading, stress fiber assembly, and focal adhesion formation. This proce

The Greenland Ice Core Chronology 2005 (GICC05) is a time scale based on annual layer counting of high-resolution records from Greenland ice cores. Whereas the Holocene part of the time scale is based on various records from the DYE-3, the GRIP, and the NorthGRIP ice cores, the glacial part is solely based on NorthGRIP records. Here we present an 18 ka extension of the time scale such that GICC05

This project, aimed to the digital documentation of archaeological sites, artifacts and cultural relics of the Western Han Dynasty, started in 2008. The anticipated outcome will be the creation of a virtual museum, based on collaborative environments, dedicated to the Western Han Dynasty and able to integrate new archaeological datasets coming from fieldwork activities (most part of them unpublish

Background Evidence for treating infantile colic with acupuncture is contradictory. Aim To evaluate and compare the effect of two types of acupuncture versus no acupuncture in infants with colic in public child health centres (CHCs). Methods A multicentre, randomised controlled, single-blind, three-armed trial (ACU-COL) comparing two styles of acupuncture with no acupuncture, as an adjunct to stan

This paper investigates the determinants of Climbing World Cup performance at a country level. An unbalanced panel of 76 countries over the years 2005 through 2008 is used. The focus of the paper is on the impact of the demographic, economic, geographic and historic predictors of the success at the Climbing World Cups. We measure the performance by the National Team rankings for each of the three

The recording and verbatim transcription of interviews is often considered to be one of the more tedious but necessary aspects of the in-depth qualitative research process. While transcription is undoubtedly a necessary methodological tool for researchers focusing specifically on discourse and language, it has also been widely adopted by researchers across the social sciences, and is sometimes adv

Increasing global production fragmentation allows for emission displacement, which may counteract advanced nation’s domestic reductions of production-related carbon emissions. Consequently, input-output analysis has become a common tool to measure countries’ carbon footprint and emission trade balances based on national consumption instead of domestically produced CO2 emissions. Nevertheless, trad

The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) is considered the primary instrument for assessing the presence and severity of obsessive-compulsive disorder (OCD). Conceptual and empirical critiques inspired the development of an updated version of the instrument, the Yale-Brown Obsessive Compulsive Scale-Second Edition (Y-BOCS-II), with a higher ceiling of OCD severity to better differentiate

The Yellow River Basin Commission (YRCC) is struggling with demand and supply water imbalances due to inter-jurisdictional rivalries, and has consequently promoted the development of water rights trading to incentivize provinces from not exceeding their allocated withdrawals in the Yellow River Basin (YRB). This thesis employs the case of Ningxia Hui Autonomous Region to examine factors that facil

Objective Second language learning continues to be a field of growing interest both in academia and everyday life. As such, a more comprehensive understanding of the best learning methods remains an important area of focus. This study aimed to investigate single-session vocabulary acquisition and neural underpinnings of language learning through Diffusion Tensor Imaging (DTI), in relation to immer

Core elements of countries’ clean energy industry success, as well as low-carbon economic development, have attracted various levels of interest from countries around the world. This thesis is based on an analysis of the EU Critical Raw Materials Act. With regard, it gives the background of what the regulation is about and its rationale. In a critical way, it has analyzed some elements of the chal

This paper aims to synthesise and build further on recent research of consumer behaviour, in order to explain how the industry affects consumer behavioural intentions towards early phase innovations. The rationale for this relies on the non-accessibility of early phase innovations and the implication that they cannot yet be experienced by consumers, which further means they cannot be objectively e