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A 60 000 year Greenland stratigraphic ice core chronology

The Greenland Ice Core Chronology 2005 (GICC05) is a time scale based on annual layer counting of high-resolution records from Greenland ice cores. Whereas the Holocene part of the time scale is based on various records from the DYE-3, the GRIP, and the NorthGRIP ice cores, the glacial part is solely based on NorthGRIP records. Here we present an 18 ka extension of the time scale such that GICC05

ADAM12/syndecan-4 signaling promotes beta(1) integrin-dependent cell spreading through protein kinase C alpha and RhoA

The ADAMs (a disintegrin and metalloprotease) comprise a large family of multidomain proteins with cell-binding and metalloprotease activities. The ADAM12 cysteine-rich domain (rADAM12-cys) supports cell attachment using syndecan-4 as a primary cell surface receptor that subsequently triggers beta(1) integrin-dependent cell spreading, stress fiber assembly, and focal adhesion formation. This proce

Effect of minimal acupuncture for infantile colic : A multicentre, three-armed, single-blind, randomised controlled trial (ACU-COL)

Background Evidence for treating infantile colic with acupuncture is contradictory. Aim To evaluate and compare the effect of two types of acupuncture versus no acupuncture in infants with colic in public child health centres (CHCs). Methods A multicentre, randomised controlled, single-blind, three-armed trial (ACU-COL) comparing two styles of acupuncture with no acupuncture, as an adjunct to stan

The IgD-binding domain of the Moraxella IgD-binding protein MID (MID962-1200) activates human B cells in the presence of T cell cytokines.

Moraxella catarrhalis immunoglobulin D (IgD)-binding protein (MID) is an outer membrane protein with specific affinity for soluble and cell-bound human IgD. Here, we demonstrate that mutated M. catarrhalis strains devoid of MID show a 75% decreased activation of human B cells as compared with wild-type bacteria. In contrast to MID-expressing Moraxella, the MID-deficient Moraxella mutants did not b

Exploring Global Climate Policy Futures and Their Representation in Integrated Assessment Models

The Paris Agreement, adopted in 2015, paved the way for a new hybrid global climate governance architecture with both bottom-up and top-down elements. While governments can choose individual climate goals and actions, a global stocktake and a ratcheting-up mechanism have been put in place with the overall aim to ensure that collective efforts will prevent increasing adverse impacts of climate chan

To facilitate a fair bioeconomy transition, stronger regional-level linkages are needed

The great hopes in Brussels that a circular bioeconomy will help bridge the growing divide between urban and rural areas and allow the hinterlands to prosper from ‘green growth’ are addressed in this article, which reflects on insights from three Nordic case studies of brown, green and blue biomass use at different levels of technology readiness. A closer examination of the forward, backward, fisc

Evaluating staging habitat quality to advance the conservation of a declining migratory shorebird, Red Knot Calidris canutus

Identifying where and when population ‘bottlenecks’ occur is critical to the conservation of migratory species, many of which are declining precipitously worldwide. Especially challenging is the evaluation of changes to staging sites. These sites are indispensable links in the migratory cycle but are typically used only briefly. We devised a field-based approach to assess the quality and carrying

Density affects plant size in the Gobi Desert

Plant size is a crucial functional trait with substantial implications in agronomy and forestry. Understanding the factors influencing plant size is essential for ecosystem management and restoration efforts. Various environmental factors and plant density play significant roles in plant size. However, how plant size responds to mean annual precipitation (MAP), mean annual temperature (MAT), and d

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This article is a revised version of the inaugural lecture delivered on 5 October2023, on the occasion of the author's appointment as Professor of History of Religions at Lund University. It opens by depicting fundamental changes in the study of the history of religions in the twentieth century, followed by biographical notes, including her research on lay Buddhism in urban Taiwan, the emphasis on

Biogeography of a Global Plant Invader : From the Evolutionary History to Future Distributions

Biological invasions pose a global challenge, affecting ecosystems worldwide and human societies. Knowledge of the evolutionary history of invasive species is critical to understanding their current invasion success and projecting their future spread. However, to date, few studies have addressed the evolutionary history and potential future spread of invaders simultaneously. In this study, we expl

Ultrastructural Heterogeneity of Carbonaceous Material in Ancient Cherts: Investigating Biosignature Origin and Preservation.

Opaline silica deposits on Mars may be good target sites where organic biosignatures could be preserved. Potential analogues on Earth are provided by ancient cherts containing carbonaceous material (CM) permineralized by silica. In this study, we investigated the ultrastructure and chemical characteristics of CM in the Rhynie chert (c. 410 Ma, UK), Bitter Springs Formation (c. 820 Ma, Australia),

Burgess shale-type biotas were not entirely burrowed away

Burgess Shale-type biotas occur globally in the Cambrian record and offer unparalleled insight into the Cambrian explosion, the initial Phanerozoic radiation of the Metazoa. Deposits bearing exceptionally preserved soft-bodied fossils are unusually common in Cambrian strata; more than 40 are now known. The well-documented decline of soft-bodied preservation following the Middle Cambrian represents

Virtually Immersed in Language: a DTI Study on Rapid Neural Plasticity and Virtual Learning Environments in L2 acquisition

Objective Second language learning continues to be a field of growing interest both in academia and everyday life. As such, a more comprehensive understanding of the best learning methods remains an important area of focus. This study aimed to investigate single-session vocabulary acquisition and neural underpinnings of language learning through Diffusion Tensor Imaging (DTI), in relation to immer

Policy Discourse on the EU Critical Raw Materials Act - Contemplation, Challenges and Comparison

Core elements of countries’ clean energy industry success, as well as low-carbon economic development, have attracted various levels of interest from countries around the world. This thesis is based on an analysis of the EU Critical Raw Materials Act. With regard, it gives the background of what the regulation is about and its rationale. In a critical way, it has analyzed some elements of the chal