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Background strain is known to influence the way a genetic manipulation affects mouse phenotypes. Despite data that demonstrate variations in the primary phenotype of basic inbred strains of mice, there is limited data available about specific metabolic fluxes in vivo that may be responsible for the differences in strain phenotypes. In this study, a simple stable isotope tracer/NMR spectroscopic pr

Diabetes is associated with low concentrations of apoM in plasma. In db/db mice, ob/ob mice as well as in the alloxan-induced diabetic mouse, the low apoM levels are paralleled by decreased expression of the apoM gene. In the latter model, insulin substitution tended to reverse the low apoM expression. It is not known whether the impairment in apoM expression can be ascribed to hyperglycemia, insu

A clone encoding farnesyl diphosphate synthase (FPPS) was obtained by PCR from a cDNA library made from young leaves of Artemisia annua. A cDNA clone encoding the tobacco epi-aristolochene synthase (eAS) was kindly supplied by J. Chappell (University of Kentucky, Lexington, KY, USA). Two fusions were constructed, i.e. FPPS/eAS and eAS/FPPS. The stop codon of the N-terminal enzyme was removed and r

The total content of dry substance (DS) and readily biodegradable material (RBM) in waste streams directed to six landfill test cells were estimated. These estimates were necessary for the evaluation of the performance of the test cells and were used to both express methane production rates on a dry matter basis, and to obtain a measurement related to acidogenesis. A hierarchial description of the

Increased nitrogen leaching from forest soils is a potential environmental problem in areas with high nitrogen deposition. In Sweden nitrogen is strongly retained in the forests, and high nitrogen leaching is not common from growing forests. However, soil water measurements on clearcuts along a deposition gradient in Sweden showed a positive correlation between increased concentration of inorganic

The effects of data uncertainty in applications of the critical loads concept were investigated on different spatial resolutions in Sweden and northern Czech Republic. Critical loads of acidity (CL) were calculated for Sweden using the biogeochemical model PROFILE. Three methods with different structural complexity were used to estimate the adverse effects of SO2 concentrations in northern Czech R

Objectives: To describe and compare the consumption of dairy products in cohorts included in the European Prospective Investigation into-Cancer and Nutrition (EPIC). Methods: Data from single 24-hour dietary recall interviews collected through a highly standardised computer-based program (EPIC-SOFT) in 27 redefined centres in 10 European countries between 1995 and 2000. From a total random sample

Highly resolved sediment stratigraphic and stable isotope records from a lake in south-central Sweden give evidence of relatively humid summers during the wide-spread cold event at c. 8200 cal. BP. A transient lake-level rise led to increased catchment erosion followed by enhanced phytoplankton production and disturbance of the Chara-dominated algal community. An associated increase in the deposit

High spin states in the neutron deficient nucleus Te-109 have been populated with the Ni-58 + Fe-54 reaction at 220 MeV and investigated through gamma-spectroscopy methods at the GASP spectrometer making use of reaction channel selection with the ISIS Si-ball. The level scheme has been extended up to an excitation energy of approximate to 12.1 MeV. The spins and parities of the observed levels are

This paper has two main objectives: (a) to put the vast body of research on Swedish as a second language (SSL) into one coherent framework; and (b) to test the predictions deriving from processability theory (Pienemann, 1998a, 1998b) for Swedish against this empirical database. We will survey the 14 most prominent research projects on SSL covering wide areas of syntax and morphology in longitudina

En jämförelse mellan den briottiska tv-serien Traffik (1989) och den amerikanska filmversionen Traffic (2000).

OBJECTIVES: To investigate whether application of insulation wool adversely affects lung volumes and increases the occurrence of symptoms of airway irritation. METHODS: Data from nationwide health check ups in 1981-93 of male construction workers born in 1955 or later were used to investigate cross sectional (n = 96,004) and longitudinal (n = 26,298) associations between lung volumes, vital capaci

Popular Abstract in Swedish Sedan årtionden ökar antalet frakturer över hela världen, och i alla ålderskategorier. Frakturer leder ofta till längre tids funktionsinskränkning, sämre livskvalitet och ibland till döden. Projektet ?Malmö Förebyggande Medicin?, an populationsbaserad, prospektiv studie av 22 444 män, medelålder 44 år, och 10 902 kvinnor, medelålder 50 år, är väl lämpad för studier av vThe number of fractures is increasing worldwide, and fractures frequently cause long-term disability, impaired quality of life and sometimes death. The Malmö Preventive Project, a population-based, prospective study, consisting of 22 444 men, mean age 44 and 10 902 women, mean age 50 years, provides data for evaluation of common public health conditions, such as fracture and diabetes. The follow-u

Nausea and emesis are common side effects of opioid drugs administered for pain relief in cancer patients. The aim of this study was to compare the anti-emetic efficacy and safety of ondansetron, placebo and metoclopramide in the treatment of opioid-induced nausea and emesis (OIE) in cancer patients. This was a multinational, multicentre, double-blind, parallel group study in which cancer patients