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Neuroblastoma (NB) is an aggressive pediatric solid tumor which often develops chemoresistance. Ferroptosis is a potential vulnerability in NB, but its interplay with chemoresistance and standard-of-care chemotherapy is not known. Here, we report that key antioxidant pathways are enriched in refractory NB, and that ferroptosis can be induced in NB through various mechanisms of action (MOA) in vitr
BACKGROUND: The management of femoral neck fractures (FNF) in elderly patients depends on comorbidities, pre-fracture mobility, any hip joint disease, and life expectancy, with treatment typically involving either hemiarthroplasty (HA) or total hip arthroplasty (THA). While cemented femoral stem fixation is standard, there is no clear consensus regarding cemented versus cementless cup fixation in
Forskning är en komplex process som ifrågasätter, undersöker och utvecklar nya aspekter av världen. På så sätt rör sig forskningsfälten hela tiden framåt. Forskningens rön och resultat sprids sedan på många sätt, till exempel genom vetenskaplig publicering, samverkan, forskarnätverk eller genom utställningar. I denna utställning presenterar biblioteket forskning från Malmö universitets fem fakulte
Due to their high reactivity, organolithium and organomagnesium addition to ketones is usually performed under inert atmosphere at low temperature. Recent work has shown that, by dissolving the substrate in deep eutectic solvents (DES), these processes can be carried out on the benchtop, in air at room temperature. Surprisingly, the organometallic reagent, added to the DES from an organic solu
Argument literacy – the ability to analyse and evaluate arguments in context – is essential in adult life. Yet, many struggle to distinguish opinions from reasoned claims, weak arguments from strong, and to understand how reasons support a claim. To address this, the Civic Argument Literacy Test (CALT) has been developed. It assesses nine argument literacy sub-skills using real-world-type examples
Do the characteristics that motivated non-Jews to rescue Jews during the Holocaust also predict morally courageous intentions in today’s high school students? Swedish students (N = 231) completed a survey assessing parental role modelling, empathic concern, risk-taking, and identification with outgroups, indicating whether they would intervene to help persecuted Jews and Muslims in various scenari
This study explores how listeners use verb constructions to describeeveryday sounds. It considers (i) how the verb constructions provide Gestaltto events in the form of activities, processes and states, and (ii) how theconstructions correspond to different aspects of a soundscape (soundsources, acoustic properties, and listener reactions). We found that verbconstructions primarily describe sound s
One of the most anticipated properties of high entropy alloys (HEA) is excellent oxidation resistance. AlxCoCrFeNi (x=0,0.3,0.6,1 mole) HEAs were synthesized by arc melting route, followed by 4 remelting operations to ensure compositional homogenization. Alloys with x = 0 and 0.3 show single phase FCC structure and x = 1 have intricate BCC+B2 structure, whereas x = 0.6 have dual phases – FCC and B
This paper analyses structural economic forces contributing to the current undersupply of affordable housing in Sweden’s third-largest city, Malmö. It operationalizes Anwar Shaikh’s theory of relative prices to analyzethe political economy of housing shortage. The paper argues that existing policy recommendations at the municipal level are primarily informed by a microeconomic approach to price fo
This paper analyses structural economic forces contributing to the current undersupply of affordable housing in Sweden’s third-largest city, Malmö. It operationalizes Anwar Shaikh’s theory of relative prices to analyze the political economy of housing shortage. The paper argues that existing policy recommendations at the municipal level are primarily informed by a microeconomic approach to price f
