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The Gaia-ESO Survey : An extremely Li-rich giant in globular cluster NGC 1261

Lithium-rich stars in globular clusters are rare. Only 14 have been found so far, in different evolutionary phases from dwarfs to giants. Different mechanisms have been proposed to explain this enhancement, but it is still an open problem. Using spectra collected within the Gaia-ESO Survey, obtained with the GIRAFFE spectrograph at the ESO Very Large Telescope, we present the discovery of the firs

The HR 1614 moving group is not a dissolving cluster

Context. The HR 1614 is an overdensity in velocity space and has for a long time been known as an old (2 Gyr) and metal-rich ([Fe=H] +0:2) nearby moving group that has a dissolving open cluster origin. The existence of such old and metal-rich groups in the solar vicinity is quite unexpected since the vast majority of nearby moving groups are known to be young. Aims. In the light of new and signifi

Analyzing Hope : The Live Possibility Account

The orthodox definition of hope suffers from an exclusion problem: it is unable to exclude subjects without hope. In fact, the orthodox definition even allows for despair to be falsely classified as hope. This problem suggests two basic desiderata for a successful analysis of hope; it should solve the exclusion problem, and it should have the resources to explain why, in a given situation, a subje

A new equation of state applied to planetary impacts : I. Models of planetary interiors

We present a new analytical equation of state (EOS), which correctly models high pressure theory and fits well to the experimental data of E-Fe, SiO2, Mg2SiO4, and the Earth. The cold part of the EOS is modeled after the Varpoly EOS. The thermal part is based on a new formalism of the Gruneisen parameter, which improves behavior from earlier models and bridges the gap between elasticity and thermo

Incidence and Associated Risk Factors of Venous Thromboembolism After Open and Laparoscopic Nephrectomy in Patients Administered Short-period Thromboprophylaxis : A Danish Nationwide Population-based Cohort Study

Objective: To report the incidence of venous thromboembolism (VTE) after nephrectomy in Denmark and explore associated risk factors. Materials and Methods: A nationwide population-based retrospective cohort study was performed. All nephrectomies from January 2010 to August 2018 were assessed for postoperative VTE events. Univariable and multivariable analyses were used to evaluate the odds ratio (

Insulation and Evaporative Resistance of Clothing for Sugarcane Harvesters and Chemical Sprayers, and Their Application in PHS Model-Based Exposure Predictions

Many workers are exposed to heat stress that can be exacerbated by the type of clothing they wear. The resulted heat strain can lead to short or long-term heat-related disorders. This study aimed to measure clothing properties of sugarcane field workers and evaluate the heat strain by an international standard, predicted heat strain model (PHS). The clothing thermal insulation and evaporative resi

In Search of the Three Crowns : Conserving, Restoring, and Reproducing Cultural Memory in Early Modern Sweden

Among the disputes concerning political, historical, and cultural priority that beleaguered Swedish-Danish relations during the sixteenth and seventeenth centuries, the quarrel over the provenance of the heraldic emblem of the Three Crowns played a central role. In Sweden the dispute led directly to the formation of an expansive, state-managed heritage industry that remains largely intact today. T

Selective tuning of spin-orbital Kondo contributions in parallel-coupled quantum dots

We use cotunneling spectroscopy to investigate spin, orbital, and spin-orbital Kondo transport in a strongly confined system of InAs double quantum dots that are parallel coupled to source and drain. In the one-electron transport regime, the higher-symmetry spin-orbital Kondo effect manifests at orbital degeneracy and no external magnetic field. We then proceed to show that the individual Kondo co

Housing Temperature-Induced Stress Is Suppressing Murine Graft-versus-Host Disease through β2-Adrenergic Receptor Signaling

Graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic cell transplantation, a potentially curative therapy for hematologic diseases. It has long been thought that murine bone marrow-derived T cells do not mediate severe GVHD because of their quantity and/or phenotype. During the course of experiments testing the impact of housing temperatures on GVHD, we discovered

Granzyme B-Mediated Activation-Induced Death of CD4+ T Cells Inhibits Murine Acute Graft-versus-Host Disease

Granzyme B (GzmB) has previously been shown to be critical for CD8(+) T cell-mediated graft-versus-host disease (GVHD) but dispensable for GVHD mediated by CD4(+) T cells. However, previous studies used high doses of CD4(+) T cells in MHC-mismatched models that caused rapid and lethal GVHD. Because of the hyperacute lethality, it is possible that the role of GzmB was concealed by the system. There

Molecular Recognition and Conformational Dynamics in Macromolecules

Computational methods gained a widespread use in drug discovery. Understanding conformational dynamics of protein and mechanisms of protein-ligand binding are two major areas in drug discovery. Molecular dynamics (MD) simulation have been routinely used to study conformational dynamics of protein and mechanisms of protein-ligand binding. In classical MD simulation, the system often remains stuck i

Vad är överturism? : En kunskapsöversikt

Turism dominerar alltmer det sociala livet i städerna. Detökade flödet av turister till vissa storstäder i Europa lämnarefter sig problem kopplat till trängsel, nedskräpning, trafik,prissättning på bostäder och missnöjesyttringar bland lokalastadsbor.Överturism beskriver ett tillstånd när det kommer så mångaturister till en plats att det får negativ påverkan på såvällokalbefolkningens livskvalitet

Flame investigations of a laboratory-scale CECOST swirl burner at atmospheric pressure conditions

Experimental and numerical studies were performed to understand the stabilization of lean premixed natural gas/air flames in a gas turbine model combustor which was equipped with a swirl burner, known as the CECOST burner, designed to replicate the flow and flame structures in an industrial gas turbine engine. The operability range, flame stabilization, and flashback were investigated employing si