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Model simplification and validation of virtual prototypes for vehicular antenna design

Wireless connectivity is becoming an important feature in cars, which together with recent developments in car design point to the need to accurately predict the performance of real antennas in simulation, to speed up the design cycle. However, it is challenging to accurately represent structurally complex real cars in simulation. This paper proposes a car model simplification approach for designi

Dynamic Channel Modeling for Indoor Millimeter-Wave Propagation Channels Based on Measurements

In this contribution, a recently conducted measurement campaign for indoor millimeter-wave (mm-wave) propagation channels is introduced. A vector network analyzer (VNA)-based channel sounder was exploited to record the channel characteristics at the frequency band from 28-30 GHz. A virtual uniform circular array (UCA) with a radius of 0.25 m was formed using a rotator with 360 steps. Moreover, by

Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype

The clinically important MAM blood group antigen is present on haematopoietic cells of all humans except rare MAM-negative individuals. Its molecular basis is unknown. By whole-exome sequencing we identify EMP3, encoding epithelial membrane protein 3 (EMP3), as a candidate gene, then demonstrate inactivating mutations in ten known MAM-negative individuals. We show that EMP3, a purported tumour sup

Proteomic investigation of protein adsorption to cerebral microdialysis membranes in surgically treated intracerebral hemorrhage patients - A pilot study

Background: Cerebral microdialysis (CMD) is a minimally invasive technique for sampling the interstitial fluid in human brain tissue. CMD allows monitoring the metabolic state of tissue, as well as sampling macromolecules such as proteins and peptides. Recovery of proteins or peptides can be hampered by their adsorption to the CMD membrane as has been previously shown in-vitro, however, protein ad

Chemical evolution of the Galactic bulge as traced by microlensed dwarf and subgiant stars : VII. Lithium

Lithium abundances are presented for 91 dwarf and subgiant stars in the Galactic bulge. The analysis is based on line synthesis of the 7Li line at 6707 Å in high-resolution spectra obtained during gravitational microlensing events, when the brightnesses of the targets were highly magnified. Our main finding is that bulge stars at sub-solar metallicities that are older than about eight billion year

A gene expression-based single sample predictor of lung adenocarcinoma molecular subtype and prognosis

Disease recurrence in surgically treated lung adenocarcinoma (AC) remains high. New approaches for risk stratification beyond tumor stage are needed. Gene expression-based AC subtypes such as the Cancer Genome Atlas Network (TCGA) terminal-respiratory unit (TRU), proximal-inflammatory (PI) and proximal-proliferative (PP) subtypes have been associated with prognosis, but show methodological limitat

Interference Modeling for Low-Height Air-to-Ground Channels in Live LTE Networks

In this letter, a recently conducted measurement campaign in two suburban scenarios for investigating the low-height air-to-ground channels is presented. A universal-software-radio-peripheral-based channel sounder on-board an unmanned aerial vehicle (UAV) was exploited to record the real-time downlink signals of the live Long Term Evolution networks. Several horizontal flights at different heights

The transport and thermodynamic characteristics of thermally oscillating phenomena in a buoyancy-driven supercritical fuel flow

To ameliorate the thermal management of a regenerative cooling system in an advanced engine, the turbulence characteristics and entropy generation in a buoyancy-driven supercritical hydrocarbon fuel flow are numerically explored in detail. Several common buoyancy criteria (Gr/Re2, Gr/Re2.7 and Grq/Grth) are established and a three-dimensional numerical model is solved with an advanced LES model. T

Text message-based lifestyle intervention in primary care patients with hypertension : a randomized controlled pilot trial

OBJECTIVE: To evaluate the feasibility of a randomized controlled pilot study with lifestyle-promoting text messages as a treatment for hypertension in primary care.DESIGN: Randomized controlled pilot trial.SETTING: Three primary health care centers in southern Sweden.SUBJECTS: Sixty patients aged 40-80 years with hypertension were included.MAIN OUTCOME MEASURES: Feasibility of the pilot study, i.

Event-based road safety assessment : A novel approach towards risk microsimulation in roundabouts

Conventional road accident risk is measured by the undesirable events/exposure ratio. Common exposure indicators are activity-based, so event-based exposure is needed to achieve event-based safety assessment. Furthermore, road safety simulation is a growing research field. The influence of some software parameters is still unknown. Besides, the use of simulation for exposure assessment is incipien

Eigenfrequency constrained topology optimization of finite strain hyperelastic structures

This paper incorporates hyperelastic materials, nonlinear kinematics, and preloads in eigenfrequency constrained density–based topology optimization. The formulation allows for initial finite deformations and subsequent small harmonic oscillations. The optimization problem is solved by the method of moving asymptotes, and the gradients are calculated using the adjoint method. Both simple and degen

Technology led to more abstract causal reasoning

Many animal species use tools, but human technical engagement is more complex. We argue that there is coevolution between technical engagement (the manufacturing and use of tools) and advanced forms of causal cognition in the human (Homo) lineage. As an analytic tool, we present a classification of different forms of causal thinking. Human causal thinking has become detached from space and time, s

The Visceral Novel Reader and Novelized Medicine in Georgian Britain

The article introduces "the visceral novel reader" as a diachronic, context-sensitive mode of novelistic reception, in which fact and fiction overlap cognitively: the mental rehearsal of the activity of seeing, hearing, smelling, tasting, and touching while reading novels and, vice versa, the mental rehearsal of novels in the act of perceiving the real world. Located at the intersection of literat

Compressively-strained GaSb nanowires with core-shell heterostructures

GaSb-based nanowires in a gate-all-around geometry are good candidates for binary p-type transistors, however they require the introduction of compressive strain to enhance the transport properties. Here, we for the first time demonstrate epitaxial GaSb-GaAsxSb1−x core-shell nanowires with a compressively strained core. Both axial and hydrostatic strain in GaSb core have been measured by X-ray dif

Inflammation, oxidative stress and genotoxicity responses to biodiesel emissions in cultured mammalian cells and animals

Biodiesel fuels are alternatives to petrodiesel, especially in the transport sector where they have lower carbon footprint. Notwithstanding the environmental benefit, biodiesel fuels may have other toxicological properties than petrodiesel. Particulate matter (PM) from petrodiesel causes cancer in the lung as a consequence of delivery of genotoxic polycyclic aromatic hydrocarbons, oxidative stress

Distal forearm fractures in immigrant groups : A national Swedish study

Objective: The aim was to analyse risk of forearm fractures in first- and second-generation immigrants to Sweden. Methods: A nationwide study of individuals 20 years of age and older was conducted. Forearm fractures were defined as at least one registered diagnosis in the National Patient Register between January 1, 1998 and December 31, 2012. Cox regression analysis was used to estimate the relat