The antiviral activities of type I IFNs have long been established. However, comparatively little is known of their role in defenses against nonviral pathogens. We examined here the effects of type I IFNs on host resistance against the model pathogenic yeast Cryptococcus neoformans. After intratracheal or i.v. challenge with this fungus, most mice lacking either the IFN-alpha/beta receptor (IFN-al

Surging outlet glaciers are important in draining large ice caps, but the mechanisms controlling surge periodicities are poorly known. We investigated a sediment sequence from the glacier-fed Lake Logurinn in eastern Iceland, and our unique annually resolved data, based on sedimentary varves, imply that Eyjabakkajokull, an outlet glacier of Vatnajokull, began surging about 2200 cal a BP (before 19

International studies on the death of elderly nursing home residents show the complexity in the understanding of the professionals who care for the dying. The aim of this study is to explore the discourses about professional caregivers caring for those dying in Denmark in the last decade. A discourse analysis inspired by Foucault was constructed. The material consists of different source documents

PURPOSE. To determine the temporal and spatial expression of Pitx2, a bicoid-like homeobox transcription factor, during postnatal development of mouse extraocular muscle and to evaluate its role in the growth and phenotypic maintenance of postnatal extraocular muscle. METHODS. Mouse extraocular muscles of different ages were examined for the expression of Pitx2 by RT-PCR, q-PCR, and immunostaining

Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to deoxyribonucleotides, the building blocks for DNA synthesis, and are found in all but a few organisms. RNRs use radical chemistry to catalyze the reduction reaction. Despite RNR having evolved several mechanisms for generation of different kinds of essential radicals across a large evolutionary time frame, this initial r

In this thesis some research questions regarding durability and quality of roads has been investigated. The questions are analyzed from an image analysis point of view and aims to be a complement to existing methods for analyzing asphalt. One important factor for the durability of the asphalt layer on roads is the affinity between the stones in the asphalt and the binder that holds the stones tog

Purpose To examine the impact of a new model of care, in which a clinical pharmacist conducts structured medication reviews and a multi-professional team collates systematic medication care plans, on the number of unidentified DRPs in a hospital setting. Methods In a prospective two-period study, patients admitted to an internal medicine ward at the University Hospital of Lund, Sweden, were includ

Elastic simulations of single-crystal copper nanobeams, of different cross section sizes and with crystallographic orientations [100] and [110] along their length directions, have been performed applying tensile mechanical loading. The molecular dynamics code LAMMPS was employed for the simulations. The Poisson's ratio, which is one of the fundamental measures of the elastic deformation behaviour

Projekt Turnstone är ett samverkansprojekt delvis finansierat av Europeiska kommissionen. Projektet är ett initiativ av Stockholmspolisens gränsbevakningsenhet. Samverkanspartners i projektet är Svenska Kustbevakningen, Region Nord öst; Helsingforspolisen; Gränsbevakningsväsendet, Finland; Polis och Gränsbevakningen i Estland; Statliga Gränsbevakningen, Lettiska republiken; och den Statliga GränssProject Turnstone is a collaborative project funded in part by the European Commission. The project is an initiative by the Stockholm Police. Collaborating partners in the project are the Swedish Coast Guard, Region Northeast; the Helsinki Police; the Gulf of Finland Coast Guard District; the Police and Border Guard Board in Estonia; the State Border Guard of the Republic of Latvia; and the State

Pulsed electric fields in combination with vacuum infusion have been utilized to impregnate cells with trehalose, aiming at substantially improving the freezing tolerance of spinach leaves. Spinach samples were first treated with ten trains of bi-polar, rectangular electric field pulses with a nominal electric field strength of 580 V/cm and immediately immersed in a 40% (w/w) solution of trehalose

The objective of this study has been to analyze the introduction and development of mineral wool building insulation in Germany, Sweden and the UK, and to examine the policy instruments that support these processes. The aim has been to improve our understanding of the role of the policy instruments. The analysis focuses on the development of the policy framework, the development of technology, the

I avhandlingen studeras migration i form av anhöriginvandring till Sverige. I fokus ställs parförhållande där parets seriositet prövas av Migrationsverket. Parets väg genom ansökningsprocessen beskrivs liksom den legala ramen kring anhöriginvandring. Vidare tar avhandlingen upp handläggning av anhöriginvandring och vilka föreställningar om anhöriginvandring och seriösa parförhållanden som finns, dImmigration for family reunion makes up about 30-50 per cent of all immigration to Sweden. The present thesis deals with the handling of applications for reunion immigration and with the comprehension of the concept of reunion immigration and of a “serious relationship”, partly by the executing officer/decision maker who apply the law, partly by the individual who is part of the couple relationshi

The stomatal index (a measure of stomatal density) of an extinct Australian Early Jurassic araucariacean conifer species, Allocladus helgei Jansson, is used to reconstruct the atmospheric carbon dioxide concentration (pCO(2)) in the Early Jurassic. The fossil leaves are preserved in a single bed, palynologically dated to late Pliensbachian (similar to 185-183 Mya). Atmospheric pCO(2) is estimated

The ATLAS Inner Detector is a composite tracking system consisting of silicon pixels, silicon strips and straw tubes in a 2 T magnetic field. Its installation was completed in August 2008 and the detector took part in data-taking with single LHC beams and cosmic rays. The initial detector operation, hardware commissioning and in-situ calibrations are described. Tracking performance has been measur

Background: Physical activity on prescription (PAP) is a successful intervention for increasing physical activity among patients with a sedentary lifestyle. The method seems to be sparsely used by general practitioners (GPs) and there is limited information about GPs' attitudes to counselling using PAP as a tool. The aim of the study was to explore and understand the meaning of prescribing physica

The overall aim was to describe and compare functional ability and health complaints of older people receiving municipal care in relation to housing and informal care, and factors associated with medical health care, municipal care and informal care. Further, the aim was to investigate agreement in needs assessments between personnel and older people and to investigate care satisfaction and health