Very early precursors of disrupted social behaviours are significant to understanding the possibility of mitigating or changing behaviours through interventions. Spontaneous play situations between infant and parent in two groups of infants aged 8.5–9 months were observed. First, a large number of videos were analysed to develop an observational schedule of play behaviour. Second, 135 videos were

We have previously shown that casein kinase 2 (CK2) negatively regulates dopamine D1 and adenosine A2A receptor signaling in the striatum. Ablation of CK2 in D1 receptor-positive striatal neurons caused enhanced locomotion and exploration at baseline, whereas CK2 ablation in D2 receptor-positive neurons caused increased locomotion after treatment with A2A antagonist, caffeine. Because both, D1 and

The effects of the position of a bluff-body on diffusion flame structures and flame instability characteristics were investigated both experimentally and numerically. The flame pattern diagram and the stability limits of the methane-air diffusion flame were investigated to evaluate the effects caused by the alternation of the position of a bluff-body. A disk-shape bluff-body was mounted 10 mm abov

Sustainable business model innovation is increasingly viewed as a lever for systems change for sustainability across businesses and industries. Banks hold a unique intermediary role in sustainable development, but also have a difficult position after the 2008 financial crisis. This paper aims to explore business models for sustainability in the service industry, particularly banking. It explores t

The paper addresses a puzzle about the proportionality requirement on self-defense due to L. Alexander. Indirectly the puzzle is also relevant to the proportionality requirement on punishment, insofar as the right to punish is derived from the right to self-defense. Alexander argues that there is no proportionality requirement on either self-defense or punishment, as long as the aggressor/offender

In this study the dosimetric properties of alumina (Al2O3) substrates found in resistors retrieved from mobile phones were investigated. Measurements of the decline of optically stimulated luminescence (OSL) generated following exposure of these substrates to ionising radiation showed that 16% of the signal could still be detected after 2 years (735 days). Further, the magnitude of the regenerativ

Incorporation of membrane proteins and internal reporter systems directly into giant vesicles, during their formation from a hydrogel surface, has emerged as a promising new concept in membrane protein characterization. Here, we provide the detailed protocol for a glucose transporter activity assay based on giant vesicles containing a fluorescent enzyme-linked reporter system internally. This assa

Background Antipsychotics form a class of drugs that should be used with caution among elderly people because of a high risk of adverse events. Despite the risks and modest effects, their use is estimated to be high, especially in nursing homes. Objective The aim was to explore the effects of medication reviews on antipsychotic drug use for elderly primary care patients and describe the extent of,

The aims of the studies included in this thesis were:• to investigate the reliability of 201thallium single photon emission computed tomography (201Tl SPECT) for preoperative diagnosis and histological staging of malignant astrocytomas in comparison with CT; • to develop a method for quantification of cerebral thallium uptake, and to evaluate the quantitative measurement in comparison with CT, for

The mechanical deformation of the wound edge resulting from negative pressure wound therapy (NPWT) at the standard setting of around -120mmHg has positive effects in promoting wound healing. However, it may cause pain to the patient during treatment. It is therefore important to study the mechanical effects of the wound edges using lower pressure and different wound fillers. Abdominal wounds were

The First World War is usually conceived as a turning point in the history of migration policy. Before the war, borders were largely open, passports were in most places abolished, and the movement of people as well as capital and traded goods was understood through an optimistic and liberal institutionalist lens. At the outbreak of the war, states reinstated passport controls, presumably as a temp

Increasing use of the ground as a thermal reservoir is expected in the near future. Shallow geothermal energy (SGE) systems have proved to be sustainable alternative solutions for buildings and infrastructure conditioning in many areas across the globe in the past decades. Recently novel solutions, including energy geostructures, where SGE systems are coupled with foundation heat exchangers, have

Zinc (Zn) is an essential micronutrient but may become toxic when present in excess. In Zn-contaminated environments, trees can be protected from Zn toxicity by their root-associated micro-organisms, in particular ectomycorrhizal fungi. The mechanisms of cellular Zn homeostasis in ectomycorrhizal fungi and their contribution to the host tree's Zn status are however not yet fully understood. The ai