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Association of cancer with moderately impaired renal function at baseline in a large, representative, population-based cohort followed for up to 30 years.

Patients with chronic renal failure show a greater incidence of malignancies. We evaluated whether moderately impaired renal function at baseline influenced risk of all cancers during long-term follow in young persons. Our cohort included 33,346 subjects, aged 26-61 years at baseline, in a representative, population-based study enrolling subjects from 1974 to 1992. Median follow-up time was 28 yea

Summary of the ATLAS experiment's sensitivity to supersymmetry after LHC Run 1-interpreted in the phenomenological MSSM

A summary of the constraints from the ATLAS experiment on R-parity-conserving supersymmetry is presented. Results from 22 separate ATLAS searches are considered, each based on analysis of up to 20.3 fb(-1) of proton-proton collision data at centre-of-mass energies of root s = 7 and 8TeV at the Large Hadron Collider. The results are interpreted in the context of the 19-parameter phenomenological mi

Measuring the local pressure amplitude in microchannel acoustophoresis

A new method is reported on how to measure the local pressure amplitude and the Q factor of ultrasound resonances in microfluidic chips designed for acoustophoresis of particle suspensions. The method relies on tracking individual polystyrene tracer microbeads in straight water-filled silicon/glass microchannels. The system is actuated by a PZT piezo transducer attached beneath the chip and driven

Atypical associations to abstract words in Broca's aphasia

Introduction Left frontal brain lesions are known to give rise to aphasia and impaired word associations. These associations have previously been difficult to analyze. We used a semantic space method to investigate associations to cue words. The degree of abstractness of the generated words and semantic similarity to the cue words were measured. Method Three subjects diagnosed with Broca’s aphasia

Antioxidant and anti-inflammatory effects of Marrubium alysson extracts in high cholesterol-fed rabbits.

The antioxidant and anti-inflammatory effects of hexane (HEXA), chloroform (CHLORO), ethyl acetate (EA) and total alcoholic (T. ALCOH) extracts of Marrubium alysson in hypercholesterolemic-fed rabbits were evaluated. Hypercholesterolemia was induced in male rabbits by high cholesterol diet (HCD) (350 mg/kg) for 8 weeks. Hypercholesterolemic rabbits were allocated into groups, treated with simvasta

A Tiny Eye Indicating A Planktonic Trilobite

Cambrian trilobites mainly lived on the sea floor, and up till now few, if any, unequivocally planktonic trilobites have been reported from earlier than the Ordovician. The late Cambrian (Furongian) to late Ordovician olenids are a distinctive group of benthic (sea-floor dwelling) or nekto-benthic trilobites. Here we show, however, that one recently described, miniaturized and very spiny olenid sp

The secretome of mesenchymal stem cells: Potential implications for neuroregeneration.

Mesenchymal stem cells have shown regenerative properties in many tissues. This feature had originally been ascribed to their multipotency and thus their ability to differentiate into tissue-specific cells. However, many researchers consider the secretome of mesenchymal stem cells the most important player in the observed reparative effects of these cells. In this review, we specifically focus on

1D self-assembly of chemisorbed thymine on Cu(110) driven by dispersion forces.

Adsorption of thymine on a defined Cu(110) surface was studied using reflection-absorption infrared spectroscopy (RAIRS), temperature programmed desorption (TPD), and scanning tunnelling microscopy (STM). In addition, density functional theory (DFT) calculations were undertaken in order to further understand the energetics of adsorption and self-assembly. The combination of RAIRS, TPD, and DFT res

Phosphodiesterase type 1, calcitonin gene-related peptide and vasoactive intestinal polypeptide are involved in the control of human vaginal arterial vessels

Objective: The vagina makes a major contribution to the normal female sexual response cycle. An increase in vaginal blood flow is considered a key event in the mechanism of sexual arousal. Recent research has focused mainly on the cyclic GMP pathway and phosphodiesterase type 5 (PDE5, cyclic GMP specific PDE) in the control of vaginal vascular smooth muscle, whereas only little is known on the rol

Multiparton interactions with an x-dependent proton size

Theoretical arguments, supported by other indirect evidence, suggest that the wave function of high-x partons should be narrower than that of low-x ones. In this article, we present a modification to the variable impact parameter framework of PYTHIA 8 to model this effect. In particular, a Gaussian hadronic matter profile is introduced, with a width dependent on the x value of the constituent bein

The impact of CCD radiation damage on Gaia astrometry - II. Effect of image location errors on the astrometric solution

Gaia, the next astrometric mission of the European Space Agency, will use a camera composed of 106 CCDs to collect multiple observations for one billion stars. The astrometric core solution of Gaia will use the estimated location of the stellar images on the CCDs to derive the astrometric parameters (position, parallax and proper motion) of the stars. The Gaia CCDs will suffer from charge transfer

Strangers in Familiar Places – Using Generic Spaces in Cross-Cultural Identity Work

Abstract in UndeterminedEmployees working across multiple cultures are exposed to a vast number of different norms and values, and consequentially work is often a struggle to retain a coherent sense of self. However, when international workers travel, they also encounter more bland spaces where familiarity and similarity are important. These spaces appear culturally generic to the Western traveler

The search for dialogue as a hindrance to understanding: practices as inter-paradigmatic research program

In a recent article Emanuel Adler and Vincent Pouliot argued that attention to 'practices' could help IR scholars overcome ontological gaps and provide a new basis, on which the discipline could be established. Four such dichotomies are particularly salient: between the material and the meaningful, the rational and the practical, between agencies and structures, and between the forces of stability

The end of HEP-specific computing as we know it?

CHEP Conferences are dedicated to a quite specific scientific computing domain, and deal with rather specialised software, developed for the needs of the High Energy Physics community. The sheer size of this community created an environment which until recently has been to a large extent isolated from the mainstream computing. There is however an emerging trend for the computing solutions to spill

Origin of Swedish hemophilia A mutations

Background: Hemophilia A (HA) has a high level of variation within the disease class, with more than 1000 mutations being listed in the HAMSTeRS database. At the same time a number of F8 mutations are present in specific populations at high frequencies. Objectives: The simultaneous presence of large numbers of rare mutations and a small number of high-frequency mutations raises questions about the

Persistent link between solar activity and Greenland climate during the Last Glacial Maximum

Changes in solar activity have previously been proposed to cause decadal- to millennial-scale fluctuations in both the modern and Holocene climates(1). Direct observational records of solar activity, such as sunspot numbers, exist for only the past few hundred years, so solar variability for earlier periods is typically reconstructed from measurements of cosmogenic radionuclides such as Be-10 and

Centrifugation as pretreatment before ultrafiltration of hemicelluloses extracted from wheat bran

Hemicelluloses recovered by alkaline extraction of wheat bran can be isolated and purified by ultrafiltration and used to produce high-value products such as barrier films for food packaging. The flux during ultrafiltration depends to a large extent on the pretreatment of the solution. It has been shown previously that dead-end filtration with kieselguhr can increase the flux during ultrafiltratio