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A Method for Assessing Resilience of Socio-Technical IT-Systems

Modern society is increasingly dependent on IT-systems. Due to this dependence it is importantthat IT-networks are designed to be resilient, meaning that they will either maintain or quickly recover theirfunctionality when exposed to strain. Simulation-based methods that consider supply network topology as wellas system responsible for repairing supply network have previously been used and found t

Plasma levels of the interleukin-1-receptor antagonist are lower in women with gestational diabetes mellitus and are particularly associated with postpartum development of type 2 diabetes

Diabetes mellitus is a group of diseases characterized by chronic hyperglycemia. Women who develops hyperglycemia for the first time during pregnancy receive the diagnosis gestational diabetes mellitus (GDM). Presently, there is no consensus about the diagnostic criteria for GDM. A majority of these women subsequently develop postpartum overt diabetes making it important to identify these patients

Graduates’ perceptions of prosthetic and orthotic education and clinical practice in Tanzania and Malawi

Background: Maintaining and improving the quality of prosthetics and orthotics education at the Tanzania Training Centre for Orthopaedic Technologists is essential for the provision of appropriate prosthetics and orthotics services in African countries. Aim: To describe how Tanzanian and Malawian graduates’ of the Diploma in Orthopaedic Technology perceive their education and how it could be impro

Experiences of providing prosthetic and orthotic services in Sierra Leone − the local staff’s perspective

Introduction: In Sierra Leone, West Africa, there are many people with disabilities in need of rehabilitation services after a long civil war. Sierra Leone is among the ten least developed countries in the world and half of the population live under the absolute poverty line with an income less than $1.25 a day. Aim: The aim of this qualitative study was to explore the experiences of prosthetic an

Curating Social Image: Experimental Evidence on the Value of Actions and Selfies

We manipulate the information subjects can share on the web concerning socially sensitive actions (public good contribution) and visibility (selfie) to determine the effect on social image, as captured by the price subjects demand for publication. The overall conclusion from the experiment is that theory about social reputation can predict subjects' social-signaling behavior. People take costly de

Cancer associated proteins in blood plasma : Determining normal variation

Protein biomarkers have the potential to improve diagnosis, stratification of patients into treatment cohorts, follow disease progression and treatment response. One distinct group of potential biomarkers comprises proteins which have been linked to cancer, known as cancer associated proteins (CAPs). We determined the normal variation of 86 CAPs in 72 individual plasma samples collected from ten i

A Statistical Atrioventricular Node Model Accounting for Pathway Switching During Atrial Fibrillation

Objective: The atrioventricular (AV) node plays a central role in atrial fibrillation (AF) as it influences the conduction of impulses from the atria into the ventricles. In the present paper, the statistical dual pathway AV node model, previously introduced by us, is modified so that it accounts for atrial impulse pathway switching even if the preceding impulse did not cause a ventricular activat

The spread of product development methodology: Exploring drivers and barriers in Swedish industry

The outcome of Design, Innovation and Product development research is often manifested as recommendations in the form of methods, but these do not always find their way into industrial application. This paper elaborates on drivers and barriers for the spread of product development methodology based on 41 interviews with managers, designers, developers and knowledge brokers. Results indicate a rang

Productive efficiency in the iron and steel sector under state planning : The case of China and former Czechoslovakia in a comparative perspective

State-ownership has often been discussed as one of the major causes of poor industrial energy efficiency performance. This paper utilizes long-run historical data on the energy and material use in one specific industrial sector – the iron and steel production – in countries with both central-planning and market-based system, with a particular focus on former Czechoslovakia paralleled with the deve

Valideringens Janusansikte : – Branschorganisationernas förhållningssätt till validering, SeQF och generiska kompetenser

I forskningsrapporten presenteras en kvalitativ intervjustudie med företrädare för branschorganisationer (sakkunniga som representerar arbetsgivarsidan) inom privat sektor som totalt representerar drygt hälften av samtliga sysselsatta i Sverige.Syftet är att studera branschorganisationers förhållningssätt såväl till egna system för validering av den enskildes reella kompetensprofil som till generi

User value and usability of a web-based mindfulness intervention for families living with mental health problems

Mental health problems affect the patients and their families, who may also need therapeutic interventions. Mindfulness interventions have shown beneficial health effects for clinical and healthy populations. A web-based mindfulness intervention was tailored to address families' needs of support and tested in a pilot intervention study. The aim of this study was to explore the participants' experi

Evolution of Mammography Screening : From Film Screen to Digital Breast Tomosynthesis

Mammography population screening has been implemented based on evidence of efficacy from randomized controlled trials (RCTs). Substantial technical developments have witnessed an evolution from screen-film mammography (SFM) to full-field digital mammography (FFDM), and more recently to digital breast tomosynthesis as a potential screening modality. Mammography's technical evolution calls for consi

Prolonged Use of Proton Pump Inhibitors as Stricture Prophylaxis in Infants with Reconstructed Esophageal Atresia

Introduction Proton pump inhibitors (PPIs) are used as prophylaxis, guarding against anastomotic stricture (AS) in the aftermath of reconstructed esophageal atresia (EA). The incidence of stricture formation was studied in this setting, comparing outcomes of 3- and 12-month PPI prophylactic regimens. Patients and Methods Patient characteristics (gestational age, birth weight, prevalence of chromo

Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells

Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. The identification of cancer cell internalizing antigens for drug targeting to the hypoxic tumour niche remains a challenge of high clinical relevance. Here we show that hypoxia down-regulates the surface proteome at the global level and, more specifically, membrane proteome internalization. We find that hyp

Avhandling / Av_handling (Dissertation / Through_action)

If we are being-of-the-world, how can we ever avoid participation? From this question Avhandling / Av_handling (Dissertation / Through_ action) unfolds. It invites to engage in an ongoing continuum of entanglements, where the moment of connection is unavoidable. This invitation demands that we are attentive to our mutual co-constitutiveness, that we take responsibility for what gets excluded as we