Purpose: To assess the performance of activities of daily living (ADL) in individuals with moderate to severe multiple sclerosis (MS). Method: A total of 12 men and 32 women with MS ( Expanded Disability Status Scale, EDSS, 6.0-8.5) were studied. The performance of personal ADL (P-ADL) and instrumental ADL (I-ADL) was assessed with the Functional Independence Measure (FIM) and the Assessment of Mo

The Ulvo Gabbro Complex (UGC) belongs to the 1.27-1.25 Ga Central Scandinavian Dolerite Group (CSDG), which manifests a major event of intra-cratonic mafic magmatism possibly related to break-up between Laurentia and Baltica. Lopolithic, layered intrusions of the UGC outcrop in east central Sweden and west central Finland. Fresh baddeleyite grains in a pegmatoidal gabbro were dated by the TIMS U-P

Iron uptake in Arabidopsis thaliana is mediated by ferric chelate reductase FRO2, a transmembrane protein belonging to the flavocytochrome b family. There is no high resolution structural information available for any member of this family. We have determined the transmembrane topology of FRO2 experimentally using the alkaline phosphatase fusion method. The resulting topology is different from tha

Lung cancer has emerged as one of the leading causes of cancer death in most developed and many developing countries of the world. In the absence of effective screening and early detection methods of lung cancer and overall poor prognosis, the 5-year survival following treatment has not improved significantly over the last two decades. It is hoped that the risk of the disease can be minimized by p

30% of the DNA in E. coli bacteria is covered by proteins. Such a high degree of crowding affects the dynamics of generic biological processes (e.g. gene regulation, DNA repair, protein diffusion etc) in ways that are not yet fully understood. In this paper, we theoretically address the diffusion constant of a tracer particle in a one-dimensional system surrounded by impenetrable crowder particles

A recently developed protocol for pulsed gradient spin echo (PGSE) NMR is applied for the size determination of multilamellar vesicles (MLVs). By monitoring the self-diffusion behavior of water, the technique yields an estimate of the homogeneous length scale λ(hom), i.e. the maximum length scale at which there is local structural heterogeneity in a globally homogeneous material. A cross-over betw

INTRODUCTION: Early identification of Alzheimer's disease (AD) is needed both for clinical trials and in clinical practice. In this study, we compared brief cognitive tests and cerebrospinal fluid (CSF) biomarkers in predicting conversion from mild cognitive impairment (MCI) to AD. METHODS: At a memory clinic, 133 patients with MCI were followed until development of dementia or until they had bee

To investigate the association between metabolic risk factors (individually and in combination) and risk of gallbladder cancer (GBC).

The protein kinase C (PKC) family of serine/threonine kinases consists of 10-15 members. The PKC isoforms have central roles in many essential cellular processes, including proliferation, apoptosis, differentiation, cytoskeletal changes, and migration. The PKC family can be subgrouped into classical, novel and atypical isoforms depending on structure and sensitivity to the activators diacylglycero

Models of small clutch sizes predict a number of invariant relationships between means and variances of measures of reproductive investment. However, empirical tests of the models have been lagging behind theoretical work. We tested the predictions using data on the mallee dragon, Ctenophorus fordi, a species where the basic assumptions of the models are likely to be fulfilled. Some, but not all,

Interest in high spatial resolution boron analyses from a geochemical perspective is related to the recognition of boron as an important tracer of chemical recycling in the Earth, due to the high solubility of boron in aqueous fluids and silicate melts. Although boron is not a nominal component in common silicates they may still contain significant B-concentrations and hence constitute important b

In this paper we describe the find of an early Mesolithic skeleton from Österöd, Bro parish, in central Bohuslän. The skeleton was originally found in 1903 by diggers in a shell bank, but was only recovered in 1933 by Johan Alin. In 2007, 14C analysis of a tooth produced the date 9025±65 BP uncalibrated, making the skeleton one of the oldest known from Scandinavia. Osteological determinations show

This volume 89 of the Yearbook for Swedish Liturgical Life is dedicated to the 2013 proposal for a new Kyrkohandbok for the Church of Sweden. It includes articles by Thomas Appelqvist, Eva Hættner Aurelius, Ingrid Dahlström, Ragnar Holte, Frank C. Senn, Bernice Sundkvist and Anna Maria Böckerman. All articles are in Swedish with summary in English except for Frank Senn's article, which is in Engli

Since their discovery more than 70 years ago antibiotic drugs have been efficient tools for treating bacterial infections, and their use has reduced the number of fatalities and the suffering from bacterial diseases. However, the use of antibiotics may lead to resistance to the same or other antibiotics. The risk of resistance appears to be larger in veterinary medicine, since antibiotics have bee

Background: Although arthroscopy of upper extremity joints was initially a diagnostic tool, it is increasingly used for therapeutic interventions. Randomized controlled trials (RCTs) are considered the gold standard for assessing treatment efficacy. We aimed to review the literature for intervention RCTs involving wrist and shoulder arthroscopy. Methods: We performed a systematic review for RCTs i

A central point of departure for this socio-legal study about online hate crimes concerns the significance of analysing and understanding social norms in relation to these crimes on the Internet. This is of importance not least when one approaches the issue of how law and the legal system may contribute towards positive developments in this field and prevent hate crimes. It is apparent that law an