An approach to helical tubular self-aggregation using C-2-symmetric self-complementary hydrogen-bonding cavity molecules
In an approach to helical self-aggregation, C-2-symmetric cavity compounds based on the fusion of the bicyclo[3.3.1] nonane and indole framework and incorporating two 2-pyridone hydrogen-bonding motifs, compounds (-)-4 (pyrrole N-butyl) and (-)-5 (pyrrole N-decyl), have been synthesized. The 2-pyridone AD-DA hydrogen-bonding motif failed to operate in the solid state as demonstrated by X-ray diffr