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Application of Machine Learning and Remote Sensing in Hydrology
Water is vital to all life on earth, but its management is becoming more difficult owing to the behavior of water in nature such as water dynamics, water movements, and different forms of water in nature. In addition, population growth, the impact of climate change, and the inappropriate use of water resources add more complexity to water resource management. The integration of natural sciences ne
Comparing Nordic forest governance : Key informant perspectives
There is a growing call for comparative analyses of forest governance to facilitate knowledge exchange for the sustainable management of Nordic forest systems, addressing the needs of societal stakeholders in enhancing both the quality and quantity of forest resources. This study traces the development of nation-wide policy instruments implemented in four Nordic countries; Finland, Sweden, Norway
Local genetic correlation via knockoffs reduces confounding due to cross-trait assortative mating
Local genetic correlation analysis is an important tool for identifying genetic loci with shared biology across traits. Recently, Border et al. have shown that the results of these analyses are confounded by cross-trait assortative mating (xAM), leading to many false-positive findings. Here, we describe LAVA-Knock, a local genetic correlation method that builds off an existing genetic correlation
Influence of final state interactions in attosecond photoelectron interferometry
Fano resonances are ubiquitous phenomena appearing in many fields of physics, e.g., atomic or molecular photoionization, or electron transport in quantum dots. Recently, attosecond interferometric techniques have been used to measure the amplitude and phase of photoelectron wave packets close to Fano resonances in argon and helium, allowing for the retrieval of the temporal dynamics of the photoio
The Impact of Urbanization-Induced Land Use Change on Land Surface Temperature
Rapid urbanization can change local climate by increasing land surface temperature (LST), particularly in metropolitan regions. This study uses two decades of remote sensing data to investigate how urbanization-induced changes in land use/land cover (LULC) affect LST in the Beijing Region, China. By focusing on the key issue of LST and its contributing variables through buffer zones, we determined
Models of Stephan's Quintet: hydrodynamic constraints on the group's evolution
We present smoothed particle hydrodynamic models of the interactions in the compact galaxy group, Stephan’s Quintet. This work is extension of the earlier collisionless N-body simulations of Renaud et al. in which the large-scale stellar morphology of the group was modelled with a series of galaxy–galaxy interactions in the simulations. Including thermohydrodynamic effects in this work, we further
N-body Simulation of the Stephan's Quintet
The evolution of compact groups of galaxies may represent one of the few places in the nearby universe in which massive galaxies are being forged through a complex set of processes involving tidal interaction, ram-pressure stripping, and perhaps finally "dry mergers" of galaxies stripped of their cool gas. Using collisionless N-body simulations, we propose a possible scenario for the formation of
Investigation of wooden floor junction in terms of sound wave propagation
In modern building construction, where light weight structures are preferred for cost reasons, the sound transmission is often a problem to be considered carefully, hence the many studies addressing this issue. Various modal methods are frequently used to investigate the vibration pattern of light weight building structures in the low frequency range. The experimental determination of time average
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we investigated common genetic variants associated with DLB in a large European multisite sample. We performed a genome wide association study in Norwegian and European cohorts of 7
Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma
Purpose: Liquid biopsy has great potential to improve the management of brain tumor patients at high risk of surgery-associated complications. Here, the aim was to explore plasma extracellular vesicle (plEV) immunoprofiling as a tool for noninvasive diagnosis of glioma.Experimental Design: PlEV isolation and analysis were optimized using advanced mass spectrometry, nanoparticle tracking analysis,
Plasma Heme Scavengers Alpha-1-Microglobulin and Hemopexin as Biomarkers in High-Risk Pregnancies
Women with established preeclampsia (PE) have increased plasma concentration of free fetal hemoglobin. We measured two hemoglobin scavenger system proteins, hemopexin (Hpx) and alpha-1-microglobulin (A1M) in maternal plasma using enzyme-linked immunosorbent assay during the late second trimester of pregnancy in women with high and low risk of developing PE. In total 142 women were included in nest
Assessment of the genetic and clinical determinants of fracture risk : Genome wide association and mendelian randomisation study
Objectives To identify the genetic determinants of fracture risk and assess the role of 15 clinical risk factors on osteoporotic fracture risk. Design Meta-analysis of genome wide association studies (GWAS) and a two-sample mendelian randomisation approach. Setting 25 cohorts from Europe, United States, east Asia, and Australia with genome wide genotyping and fracture data. Participants A discover
CCE in fixed-T panels
The presence of unobserved heterogeneity and its likely detrimental effect on inference has recently motivated the use of factor-augmented panel regression models. The workhorse of this literature is based on first estimating the unknown factors using the cross-section averages of the observables, and then applying ordinary least squares conditional on the first-step factor estimates. This is the
CSF and blood biomarkers for Parkinson's disease
In the management of Parkinson's disease, reliable diagnostic and prognostic biomarkers are urgently needed. The diagnosis of Parkinson's disease mostly relies on clinical symptoms, which hampers the detection of the earliest phases of the disease—the time at which treatment with forthcoming disease-modifying drugs could have the greatest therapeutic effect. Reliable prognostic markers could help
A systematic review of health-related quality of life in children and adolescents during treatment for cancer
Health-related quality of life (HRQL) is a multidimensional concept which captures the individual’s perception of treatment burden. Evaluating HRQL during treatment for childhood cancer provides insight into the burden of the treatment from the child’s and/or parent’s perspective.In this review, we aimed to describe Patient-Reported Outcome Measures (PROMs) used to measure HRQL during treatment, d
Assessing aspects of solution-based chemical synthesis to convert waste Si solar cells into nanostructured aluminosilicate crystals
The end-of-life recycling of crystalline silicon photovoltaic (PV) modules and the utilisation of waste is of fundamental importance to future circular-economy societies. In the present work, the wet-chemistry synthesis route - a low-temperature dissolution-precipitation process - was explored to produce aluminosilicate minerals from waste c-Si solar cells. Nanostructured crystals were produced in
Comparative analysis examining patterns of genomic differentiation across multiple episodes of population divergence in birds
Heterogeneous patterns of genomic differentiation are commonly documented between closely related populations and there is considerable interest in identifying factors that contribute to their formation. These factors could include genomic features (e.g., areas of low recombination) that promote processes like linked selection (positive or purifying selection that affects linked neutral sites) at
Transcranial optical imaging reveals a pathway for optimizing the delivery of immunotherapeutics to the brain
Despite the initial promise of immunotherapy for CNS disease, multiple recent clinical trials have failed. This may be due in part to characteristically low penetration of antibodies to cerebrospinal fluid (CSF) and brain parenchyma, resulting in poor target engagement. We here utilized transcranial macroscopic imaging to noninvasively evaluate in vivo delivery pathways of CSF fluorescent tracers.
Outstanding problems in the phenomenology of hard diffractive scattering
This paper is a summary of the discussion within the Diffractive and Low-x Physics Working Group at the 1999 Durham Collider Workshop of the interpretation of the Tevatron and HERA measurements of inclusive hard diffraction.