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Modeling vegetation and ecosystem responses to climate change and fire regime

Climatic fire danger will likely increase because more droughts and heat-waves are caused by climate change. Climate change can shift fires from occurring only rarely to regularly in ecosystems not until now adapted to fire. We applied dynamic vegetation-fire models to investigate these future responses. The future of fire in Mediterranean-type ecosystems depends strongly on changes in vegetation

Revision of river terrace geochronology in the Orawa-Nowy Targ Depression, south Poland : insights from OSL dating

Geochronologies of intramontane depression (basin) fluvial sedimentation enable to identify through time periods of alluviation and river erosion, and date fault movement. For these purposes the optically stimulated luminescence (OSL) dating has been applied to evaluate and to develop a geochronological framework of river terraces. We study the age of river terrace deposits of the Czarny Dunajec R

RIFM fragrance ingredient safety assessment, isobornyl isovalerate, CAS registry number 7779-73-9

This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization potential, as well as, environmental safety. Data from the suitable read across analog isobornyl acetate (CAS # 125-12-2) show that this material is not genotoxic, provided a MOE> 100 for the repeated d

Assessment of value for resource allocation in cancer care

There has been an increased interest in ways of measuring the value of new therapeutic options in oncology. An example of this in a European context is the ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS). The purpose of this study is to analyse how the value scales, exemplified with ESMO-MCBS, developed mainly to assist decisions by physicians, relate to other measures of clinical benefit and

Patterns of metastasis in colon and rectal cancer

Investigating epidemiology of metastatic colon and rectal cancer is challenging, because cancer registries seldom record metastatic sites. We used a population based approach to assess metastatic spread in colon and rectal cancers. 49,096 patients with colorectal cancer were identified from the nationwide Swedish Cancer Registry. Metastatic sites were identified from the National Patient Register

Cancer heterogeneity determined by functional proteomics

Current manuscript gives a synopsis of tumor heterogeneity related to patient samples analyzed by proteomics, protein expression analysis and imaging mass spectrometry.First, we discuss the pathophysiologocal background of cancer biology as a multifactorial and challenging diseases. Disease pathology forms the basis for protein target selection. Therefore, histopathological diagnostics and grading

Sponges of the family Axinellidae (Porifera : Demospongiae) in Indonesia

Nine species in five genera of the family Axinellidae, including three new species, Axinella badungensis sp. nov., A. ba-linensis sp. nov. and Phycopsis pesgalli sp. nov. are recorded from Indonesian waters within the limits of the Western Coral Triangle province. Descriptions and discussion of those species are presented here. Four new combinations, Pha-kettia arbora (Sim, Kim & Byeon, 1990)

Surface Partitioning in Organic-Inorganic Mixtures Contributes to the Size-Dependence of the Phase-State of Atmospheric Nanoparticles

Atmospheric particulate matter is one of the main factors governing the Earth's radiative budget, but its exact effects on the global climate are still uncertain. Knowledge on the molecular-scale surface phenomena as well as interactions between atmospheric organic and inorganic compounds is necessary for understanding the role of airborne nanoparticles in the Earth system. In this work, surface c

Engaging local industry in the development of basic research infrastructure and instrumentation - The case of HIE-ISOLDE and ESS Scandinavia

Two world-class research facilities, the European Spallation Source, ESS, and the light-source facility MAX-IV, are being built in southern Sweden. They will primarily, when completed, be used for research in the fields of material sciences, life sciences, medicine and pharmacology. Their construction and the operation and maintenance of them for many years will create new business opportunities f

Combining Text Semantics and Image Geometry to Improve Scene Interpretation

Inthispaper,wedescribeanovelsystemthatidentifiesrelationsbetweentheobjectsextractedfromanimage. We started from the idea that in addition to the geometric and visual properties of the image objects, we could exploit lexical and semantic information from the text accompanying the image. As experimental set up, we gathered a corpus of images from Wikipedia as well as their associated articles. We ext

Mining semantics for culturomics: towards a knowledge-based approach

The massive amounts of text data made available through the Google Books digitization project have inspired a new field of big-data textual research. Named culturomics, this field has attracted the attention of a growing number of scholars over recent years. However, initial studies based on these data have been criticized for not referring to relevant work in linguistics and language technology.

Adsorption of hydrogen on stable and metastable Ir(100) surfaces

Using the combination of high resolution core level spectroscopy and density functional theory we present adetailed spectroscopic study for all clean and hydrogen covered phases of Ir(100). The results are complementedby an investigation of the hydrogen desorption process from various phases using temperature programmeddesorption spectroscopy and scanning tunneling microscopy. In total, all experi

Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation in Sweden, long-term results from all patients treated in 1994-2009

High-dose melphalan and autologous stem cell transplantation (HDM/ASCT) is widely used in immunoglobulin light chain (AL) amyloidosis, but the benefit is debated mainly because of the high treatment-related mortality (24% in a randomised study comparing HDM/ASCT with oral melphalan/dexamethasone). We report here on the long-term outcome of all patients treated with HDM/ASCT for AL amyloidosis in S

Exercise therapy versus arthroscopic partial meniscectomy for degenerative meniscal tear in middle aged patients : Randomised controlled trial with two year follow-up

Objective To determine if exercise therapy is superior to arthroscopic partial meniscectomy for knee function in middle aged patients with degenerative meniscal tears. Design Randomised controlled superiority trial. Setting Orthopaedic departments at two public hospitals and two physiotherapy clinics in Norway. Participants 140 adults, mean age 49.5 years (range 35.7-59.9), with degenerative media

Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

Genome-wide association studies (GWASs) have identified 19 susceptibility loci for Alzheimer’s disease (AD). However, understanding how these genes are involved in the pathophysiology of AD is one of the main challenges of the “post-GWAS” era. At least 123 genes are located within the 19 susceptibility loci; hence, a conventional approach (studying the genes one by one) would not be time- and cost

High prevalence of thyroid autoantibodies at diagnosis of insulin-dependent diabetes mellitus in Swedish children

The prevalence of thyroglobulin autoantibodies and that of thyroid peroxidase autoantibodies were studied in serum samples from 52 children with insulin-dependent diabetes mellitus, sampled at diagnosis and before the start of insulin treatment, with 386 non-diabetic schoolchildren (11 to 13 years of age) serving as control subjects. Using exactly the same sensitive solid-phase immunosorbent radio

UBER between Labour and Competition Law

UBER is often described as disruptive innovator. This paper examines whether the UBER model disrupts the classical competition analysis thereby creating the uber-cartel, a cartel to which the normal competition rules don’t apply. This working paper on UBER and UBER-like business models examines issues that such a model faces with regard to labour and competition law with a particular focuses on th