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Acoustic control of suspended particles in micro fluidic chips

A method to separate suspended particles from their medium in a continuous mode at microchip level is described. The method combines an ultrasonic standing wave field with the extreme laminar flow properties obtained in a silicon micro channel. The channel was 750 mum wide and 250 mum deep with vertical side walls defined by anisotropic wet etching. The suspension comprised "Orgasol 5mum" polyamid

An endogenous retroviral long terminal repeat is the dominant promoter for human beta 1,3-galactosyltransferase 5 in the colon

LTRs of endogenous retroviruses are known to affect expression of several human genes, typically as a relatively minor alternative promoter. Here, we report that an endogenous retrovirus LTR acts as one of at least two alternative promoters for the human beta1,3-galactosyltransferase 5 gene, involved in type 1 Lewis antigen synthesis, and show that the LTR promoter is most active in the gastrointe

Cystatin C as a marker of GFR - history, indications, and future research

Objective: To summarize recent knowledge on the small molecular weight protein cystatin C (cys-C) and its use as a marker of the glomerular filtration rate (GFR). Methods: A multinational expert meeting was held in April 2002 in Marburg, Germany. Contributors summarized their main findings. Conclusions: Cys-C is at least equal if not superior to serum creatinine as a marker of GFR. The independenc

Influence of the particle size and particle size ratio on the morphology and viscoelastic properties of bimodal hard/soft latex blends

The morphology and viscoelastic properties of films prepared from bimodal latex blends containing equal weight fractions of soft and hard latex particles were investigated as a function of the particle sizes and the particle size ratio (soft particle diameter/hard particle diameter). Minimum film formation temperature (MFT) measurements were associated with transmission electron microscopy (TEM) t

Bulky DNA adducts, 4-aminobiphenyl-haemoglobin adducts and diet in the European Prospective Investigation into Cancer and Nutrition (EPIC) prospective study

In contrast to some extensively examined food mutagens, for example, aflatoxins, N-nitrosamines and heterocyclic amines, some other food contaminants, in particular polycyclic aromatic hydrocarbons (PAH) and other aromatic compounds, have received less attention. Therefore, exploring the relationships between dietary habits and the levels of biomarkers related to exposure to aromatic compounds is

Measurements of urea and glucose in aqueous solutions with dual-beam near-infrared Fourier transform spectroscopy

This study investigates the use of a dual-beam, optical null, FT-IR spectrometer to measure trace organic components in aqueous solutions in the combination band region 5000-4000 cm(-1). The spectrometer may be used for both single- and dual-beam measurements, thereby facilitating comparison of these two modes of operation. The concentrations of aqueous solutions of urea and glucose in the ranges

Palms tracking climate change

Aim Many species are currently expanding their ranges in response to climate change, but the mechanisms underlying these range expansions are in many cases poorly understood. In this paper we explore potential climatic factors governing the recent establishment of new palm populations far to the north of any other viable palm population in the world. Location Southern Switzerland, Europe, Asia and

Complex Nature of the Genome in a Wine-spoilage Yeast, Dekkera bruxellensis.

When the genome organization of thirty native isolates belonging to a wine-spoilage yeast Dekkera/Brettanomyces bruxellensis, a distant relative of Saccharomyces cerevisiae, was examined, the number of chromosomes varied drastically, from 4 to at least 9. When single gene probes were used in Southern analysis, the corresponding genes usually mapped to at least two chromosomal bands, excluding a si

Synthesis, Structure and Properties of MelamineB pTHF-Urethane Supramolecular Compounds.

The properties of melamine based supramolecular compounds have been studied with rheological, thermal, mechanical, dielectric and scattering techniques and compared with similar covalently bonded materials. The complexes are based on a linear pTHF-diol ([bar M ]n = 1 000) connected via a diisocyanate with melamine. The results obtained show that, despite of the material's low molecular weight (< 2

Precise determination of the isotopic composition of Sn using MC-ICP-MS

High precision isotopic measurements of Sn in two commercially available high purity materials and a previously analysed cassiterite from Straits Settlement, Malaysia, are presented as a basis for a new measurement procedure using the Micromass IsoProbe MC-ICP-MS. The results show that under optimised instrumental conditions two laboratory calibration standard solutions (Johnson-Matthey Puratronic

Degradation of low density polyethylene during extrusion. I. Volatile compounds in smoke from extruded films

Many problems with odor and taste in food packaging can be traced to degradation of the packaging materials during processing. From this starting point, the degradation of polyethylene in a commercial extrusion coating process was studied by analyzing degradation products present in smoke sampled at the extruder die orifice. Two low-density polyethylenes, A and B, with similar melt flow indexes an

Effects of macroeconomic trends on social security spending due to sickness and disability

Objectives. We analyzed the relationship between macroeconomic conditions, measured as unemployment rate and social security spending, from 4 social security schemes and total spending due to sickness and disability. Methods. We obtained aggregated panel data from 13 Organization for Economic Cooperation and Development member countries for 1980-1996. We used regression analysis and fixed effect m

Occupational exposure to endocrine-disrupting compounds and biliary tract cancer among men

Objectives This study investigated the association between cancer of the extrahepatic biliary tract and exposure to endocrine-disrupting compounds. Methods Altogether 183 men with histologically confirmed carcinoma of the extrahepatic biliary tract and 1938 matched controls were interviewed between 1995 and 1997 in the frame of an international multicenter case-control study in six European countr

Treatment of high-temperature rinsing water from a degreasing plant by reverse osmosis

In the manufacture of heat-exchangers, it is of great importance that the heat-exchanger plates be thoroughly cleaned before being sealed. At a Swedish heat-exchanger manufacturer, oil, grease and other impurities are removed in a washing plant consisting of three stages: a degreasing tank and two rinsing tanks. The possibility of improving the cleanliness of the heat-exchanger plates, without inc

Hypomotor seizures in infants and children.

PURPOSE: Hypomotor seizures (characterized by diminished behavioral activity with indeterminate level of consciousness) have been identified as an important seizure type in infants. Our goal was to investigate further the clinical and EEG features of hypomotor seizures. METHODS: We retrospectively reviewed 110 hypomotor seizures from 34 patients recorded with video-EEG. RESULTS: Twenty-seven (79%)

Low glutathione peroxidase in rdl mouse retina increases oxidative stress and proteases

Malondialdehyde, reduced glutathione, glutathione peroxidase, glutathione reductase and cysteine protease cathepsins at postnatal (PN) days 2, 7, 14, 21 and 28 in controls (wt) and the retinal degeneration 1 (rd1) mouse model for retinitis pigmentosa retinas were measured to determine oxidative stress. In PN28 wt and PN2 rd1 retinas, elevated malondialdehyde and low glutathione peroxidase activity

How common are psychotic and bipolar disorders? A 50-year follow-up of the Lundby population.

Background: The purpose was to present the prevalence of all psychotic and bipolar (BP) disorders in a total general population (n=3563), which has been followed from 1947 to 1997. Materials and Methods: Best-estimate consensus DSM-IV diagnoses, supported by data from interviews, case notes, registers and key-informants, were assessed. The period prevalence from 1947 to 1997 and the lifetime preva

Novel migraine therapy with calcitonin gene-regulated peptide receptor antagonists

Primary headaches, for example, migraine and cluster headaches represent the most prevalent neurological disorders, affecting up to 15 - 20% of the adult population. There is a clear association between head pain and the release of calcitonin gene-related peptide (CGRP). In this review the role of CGRP in human cranial circulation is described and the role for specific CGRP antagonism elucidated.