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Layering and parallel policy making – Complementary concepts for understanding implementation challenges related to sustainable mobility

This paper is focused on implementation challenges related to the integration of sustainable mobility in strategic local/regional land use and transport planning. The work was based on a case study of Stockholm, Sweden, focusing on four current plans and strategies of key importance for sustainable mobility. We identify and discuss implementation challenges related to sustainable mobility using a

The generative mechanisms of healthcare digitalization

Digitalization is considered key to meeting the challenges that face the healthcare sector. However, the results of digitalization initiatives have often been disappointing and the literature has provided a fragmented understanding of the mixed results. While previous studies have generally focused on the advantages and the barriers of adopting healthcare IS, little attention has been paid to unea

Salivary cortisol and self-reported stress among persons with environmental annoyance

OBJECTIVES: Increased vulnerability to stress has been suggested as a possible mechanism behind medically unexplained conditions such as sensitivity to electricity and common smells. This study examined whether subjective environmental annoyance among the general population is associated with increased physiological reactivity or subjective stress scores.METHODS: Four groups were studied (N=141):

Two-photon double ionization of neon using an intense attosecond pulse train

We present a demonstration of two-photon double ionization of neon using an intense extreme ultraviolet (XUV) attosecond pulse train (APT) in a photon energy regime where both direct and sequential mechanisms are allowed. For an APT generated through high-order harmonic generation (HHG) in argon we achieve a total pulse energy close to 1μJ, a central energy of 35 eV, and a total bandwidth of ∼30 e

Long-term results after infantile Blount's disease

A long-term follow-up of 49 patients with an average age of 38 years (range: 25-67 years) who had experienced infantile Blount's disease was done. Thirty-seven patients had bilateral disease, giving a total of 86 affected knees. Thirty-eight knees had conservative or no treatment during childhood; 13 were treated by epiphysiodesis, and 35 by osteotomy. At follow-up, 11 knees showed arthrosis, and

Extracellular Matrix Alterations in Patients with Different Phenotypes of Asthma.

AbstractAsthma is a chronic disease that affects approximately 300 million people worldwide, and the prevalence is increasing. It has become clear that asthma is a highly heterogeneous disease, with overlapping symptoms but with diverse immunopathology and clinical phenotypes. Also, a significant proportion of asthma patients have remaining symptoms despite treatment. In addition to different phen

Reduction of trans-dichloro- and trans-dibromo-tetracyanoplatinate(IV) by L-methionine

Reduction of trans-[Pt(CN) 4 X 2 ] 2- (X = Cl or Br) [as model compounds for antitumour-active platinum(IV) pro-drugs] to [Pt(CN) 4 ] 2- by L-methionine, MeSR, has been studied at 25 °C in the range 0 < pH < 12 (X = Cl) and 0 < pH < 6 (X = Br) by use of stopped-flow spectrophotometry. The stoichiometry is [Pt IV ] : [MeSR] ≈ 1 : 1; the reaction products are methionine S-oxide and [Pt(CN) 4 ] 2- asReduction of trans-[Pt(CN)4 X2]2- (X = Cl or Br) as model compounds for antitumour-active platinum(IV) pro-drugs, to [Pt(CN)4]2- by L-methionine, MeSR, has been studied at 25 °C in the range 0 < pH < 12 (X = Cl) and 0 < pH < 6 (X = Br) by use of stopped-flow spectrophotometry. The stoichiometry is [Pt IV] : [MeSR] ≈ 1 : 1; the reaction products are methionine S-oxide and [Pt(CN)4]2- as identified

Exploring the opportunities and barriers of using prefabricated house components

To satisfy customers’ desires with a maintained efficiency of the production process is a challenge for many house construction companies. Houses are one-off projects with a production process characterized by variability and complexity that often lead to unpredicted costs. Prefabricated component solutions could possibly solve these issues through modularization, mass customization and delayed prTo satisfy customers’ desires with a maintained efficiency of the production process is a challenge for many house construction companies. Houses are one-off projects with a production process characterized by variability and complexity that often lead to unpredicted costs. Prefabricated component solutions could possibly solve these issues through modularization, mass customization and delayed pr

Theoretical Modeling of Water Exchange on [Pd(H2O)4]2+, [Pt(H2O)4]2+, and trans-[PtCl2(H2O)2]

SynopsisOptimized structures describing key features of the potential energy surface for water exchange at three planar d8 centers have been calculated using ab initio density functional theory. The local density approximation (LDA), including relativistic corrections for Pt, gives good agreement with the available experimental ground state structural data. LDA binding energies together with expli

Multivariate linear regression modelling of lung weight in 24,056 Swedish medico-legal autopsy cases

Heavy combined lung weight at autopsy is a non-specific autopsy finding associated with certain causes of death such as intoxication. There is however no clear definition of what constitutes "heavy" lung weight. Different reference values have been suggested but previous studies have been limited by small select populations and only univariate regression has been attempted. The aim of this study w

Targeting prostate cancer stem cells with alpha-particle therapy

Modern molecular and radiopharmaceutical development has brought the promise of tumor-selective delivery of antibody-drug conjugates to tumor cells for the diagnosis and treatment of primary and disseminated tumor disease. The classical mode of discourse regarding targeted therapy has been that the antigen targeted must be highly and homogenously expressed in the tumor cell population, and at the

Disintegrated experience : The dissociative disorders revisited

We present proposed changes to the dissociative disorders section of the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders and review the concept of pathological and nonpathological dissociation, including empirical findings on the relations between trauma and dissociative phenomenology and between dissociation and hypnosis. The most important proposals include the creation

Reaction of Peroxomonosulfate Radical with Manganese(II) in Acidic Aqueous Solution. A Pulse Radiolysis Study

The reaction between the SO5– radical and MnII has been proposed to be the most important process for regeneration of MnIII in the MnIII/II-catalysed autoxidation of SIV in acidic aqueous solution. In the present study, the second-order rate constant for this reaction has been determined at pH 3. 0 and 10 mmol dm–3 ionic strength by use of pulse radiolysis. The study was performed in the presence The reaction between the SO5– radical and MnII has been proposed to be the most important process for regeneration of MnIII in the MnIII/II-catalysed autoxidation of SIV in acidic aqueous solution. In the present study, the second-order rate constant for this reaction has been determined at pH 3. 0 and 10 mmol dm–3 ionic strength by use of pulse radiolysis. The study was performed in the presence