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Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin EP4-R essential for agonist-induced beta-arrestin1 recruitment that differs from the apparent principal phosphorylation site.

hEP4-R (human prostaglandin E2 receptor, subtype EP4) is a Gs-linked heterotrimeric GPCR (G-protein-coupled receptor). It undergoes agonist-induced desensitization and internalization that depend on the presence of its C-terminal domain. Desensitization and internalization of GPCRs are often linked to agonist-induced b-arrestin complex formation, which is stabilized by phosphorylation. Subsequentl

Analysis of the effects of outdoor and accelerated ageing on the optical properties of reflector materials for solar energy applications

Lifetime tests of solar reflector materials are eligible prior to application, to prove the stability of the optical properties. In this work, six reflector materials were aged outdoors and in a climatic test chamber. The surfaces of the samples were inspected using profilometry and optical microscopy. The total and specular reflectance spectra were measured using spectrophotometry and the weighte

Towards an Understanding of Symbolic Aspects of Professional Information: An Analysis of the Nursing Knowledge Domain

The aim of this article is to contribute to the development of the domain analytical approach by using tools from the theory of professions. This is accomplished by showing how the symbolic values of professional information can create, sustain, and alter professional interests, power relations, and occupational identities. By taking this approach, the importance of considering the issues of power

Traditional versus agricultural lifestyle among Shuar women of the Ecuadorian Amazon: Effects on leptin levels

Leptin is a key biological marker related to energy balance and development of diabetes and cardiovascular diseases. Its levels are increased in populations with a high degree of the metabolic syndrome. Life history of evolution has, however, largely taken place under the ecological context of hunting and gathering. In this study, we explored whether the first steps of transition to sedentary agri

Examples of Peirce decomposition for compact simple Kantor triple systems

Every tripotent which is a left unit of a compact simple Kantor triple system defines a decomposition of the space of the triple into a direct sum of four components, hence it defines a generalization of the Peirce decomposition for Jordan triple systems. We give examples of the Peirce decomposition for classical compact simple Kantor triple systems and for (exceptional) compact simple Kantor trip

Electron mean free path for GaAs(100)-c(4x4) at very low energies

Electron mean free path (MFP) was determined by the angular resolved photoemission in 10-40 eV energy range for GaAs(100)-c(4 x 4) by the overlayer method. The investigation was based on the attenuation of the normal photoemission intensity of the Al 2p line from the molecular-beam-epitaxy grown GaAlAs layer buried four monolayers of GaAs below the surface. The energy dependence of the MFP shows a

Variational surface interpolation from sparse point and normal data

Many visual cues for surface reconstruction from known views are sparse in nature, e.g., specularities, surface silhouettes, and salient features in an otherwise textureless region. Often, these cues are the only information available to an observer. To allow these constraints to be used either in conjunction with dense constraints such as pixel-wise similarity, or alone, we formulate such constra

Riskanalys av två ytbehandlingsindustrier i Jönköpings län

Riskanalysen har genomförts av institutionen för brandteknik, Lunds tekniska högskola, i samarbete med räddningstjänsten i Jönköping. Riskanalysen gjordes på uppdrag av Statens räddningsverk och ingår som en del i deras projekt om kommunal riskhantering. De inblandade har från brandteknik varit Göran Holmstedt (projektledare), och Jan-Erik Öst. Från räddningstjänsten i Jönköping har Clas Lövgren d

Pharmacological treatment of osteopenia induced by gastrectomy or ovariectomy in young female rats

Background Both gastrectomy (GX) and ovariectomy (OVX) induce osteopenia in man and experimental animals. The present study addresses the question - can alendronate, estrogen or parathyroid hormone (PTH) be used to treat established GX- or OVX -evoked osteopenia? Methods Rats were GX-, OVX- or SHAM-operated 8 weeks before starting the treatment with drugs. Each group was then treated for 8 weeks

A database of exposures in the rubber manufacturing industry: Design and quality control

The concerted action EXASRUB was initiated to create a database management system for information on occupational hygiene measurements that could be used to develop exposure models in the European rubber manufacturing industry. Quality of coding was assessed by calculating percentages of agreement and Cohen's kappa statistics (kappa) for an intra- and inter-centre recoding of randomly selected sub