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After work, På spaning efter mening i den automatiserade staden

Få aspekter av våra liv bidrar lika mycket till vår identitet och som källa till men- ing som arbetet. Samtidigt är behovet av mänsklig arbetskraft för att tillfredsställa grundläggande mänskliga behov mindre än någonsin, en tendens som kan komma att accelereras ytterligare de närmaste årtiondena till följd av ny teknologi. I mitt examensarbete försöker jag ta mig an frågan vad arbete egentligen äFew aspects of our lives contribute as much to our identity and sense of meaning as work. At the same time, the need for human labour to satisfy basic human needs is lower than ever—a trend that may accelerate further in the coming decades due to new technologies. In my thesis, I attempt to explore the question of what work actually is, the role it plays in our lives and in society, how it has bee

Enhanced Rates of Subpicosecond Energy Transfer in Blue-Shifted Light Harvesting LH2 Mutants of Rhodobacter sphaeroides

Energy transfer within various LH2 antenna complexes of the photosynthetic purple bacteria Rhodobacter sphaeroides and Rhodopseudomonas acidophila has been studied at 77 K using tunable femtosecond and subpicosecond infrared pulses. The complexes examined include the wild-type B800-850 as well as three different specifically mutated complexes. The site-directed mutant strains were altered at posit

Energy transfer in spectrally inhomogeneous light-harvesting pigment-protein complexes of purple bacteria

Energy transfer within the peripheral light-harvesting antenna of the purple bacteria Rhodobacter sphaeroides and Rhodopseudomonas palustris was studied by one- and two-color pump-probe absorption spectroscopy with approximately 100-fs tunable pulses at room temperature and at 77 K. The energy transfer from B800 to B850 occurs with a time constant of 0.7 +/- 0.05 ps at room temperature and 1.8 +/-

Photosynthetic light-harvesting : Reconciling dynamics and structure of purple bacterial LH2 reveals function of photosynthetic unit

Great progress in the study of structure and dynamics of photosynthetic light-harvesting pigment-protein complexes has recently resulted in detailed understanding of the light-harvesting and light-conversion processes of photosynthesis. We review and discuss recent results on the elementary excitation transfer dynamics of the purple bacterial LH2 peripheral complex. When combining the information

Stand-alone transcriptional immune response prediction in primary triple-negative breast cancer

Triple-negative breast cancer (TNBC) accounts for 10-20% of primary breast cancers and often has early relapses and aggressive progression. An activated tumour immune response can be prognostic in treatment-naive and chemotherapy-treated TNBC patients and may be assessed using gene expression data. We derived a stand-alone predictor for a proposed immunomodulatory transcriptional TNBC subtype in a

Dynamic assessment of proliferation to guide response-adapted therapy in the setting of neoadjuvant chemotherapy in ER+/HER2- breast cancer

Biomarkers for evaluating response to neoadjuvant chemotherapy (NACT) in ER+/HER2- breast cancer remain limited. This study explores the impact of NACT on tumor proliferation dynamics and its association with relapse-free interval (RFI) among 175 patients with early ER+/HER2- breast tumors. Proliferation was assessed at baseline, after completing two NACT cycles, and in the residual tumor using Ki

Concrete Complexes as Vague Objects

This essay examines whether ontological vagueness can coherently resolve Peter Unger’s "The Problem of the Many" — the dilemma that ordinary objects like clouds or stones must either not exist or exist in overwhelming multiplicity due to their indeterminate boundaries. While Unger rejects vague objects as incoherent, attributing vagueness instead to semantic imprecision, this essay defen

The Silver Generation’s perception of sustainable fashion marketing

Aim: The aim of this paper is to examine how Baby Boomers perceive fashion brands sustainability and what that implies for brands marketing strategy. Since Baby Boomers are the second largest generation and most research has been targeting the younger generation, although the baby boomer generation has a higher economic power. Approach: We conducted a qualitative study using eight interviews with

A perfect match? Using co-branding theory to determine the brand fit between sports teams and athlete brands

Purpose: In recent years, professional sports have become increasingly globalized and commercialized. This is reflected in the increased strategic application of branding across teams, athletes and other stakeholders in the sports industry to differentiate themselves, secure sponsorships, and enhance fan engagement. As athletes increasingly recognize the value of their personal brands, understandi

Ambulanssjuksköterskors och distriktssköterskors erfarenheter av samverkan i det egna hemmet hos äldre patienter

Bakgrund: Allt fler personer vårdas i det egna hemmet trots avancerad sjukdom och med avancerad medicinsk behandling. Den mer avancerade vården sågs tidigare som den typ av vård som gavs inneliggande på sjukhus. Patienters hem utgör distriktssköterskors arbetsplats. Ibland behöver ambulans tillkallas och då ska distriktssköterskor och ambulanssköterskor samverka med varandra kring äldre patienter.

Antibiotic-induced mitochondrial dysfunction : Exploring tissue-specific effects on HEI-OC1 cells and peripheral blood mononuclear cells

Antibiotics are crucial in treating infectious diseases, particularly in intensive care unit patients, but they can lead to side effects such as ototoxicity. A mechanism for this is antibiotics targeting mitochondrial components in eucaryotic cells, due to their resemblance of those in bacteria. Here we investigate how five classes of antibiotics (carbapenems, fluoroquinolones, aminoglycosides, gl

Vaccine effectiveness against COVID-19 hospitalisation in adults (≥ 20 years) during Alpha- and Delta-dominant circulation : I-MOVE-COVID-19 and VEBIS SARI VE networks, Europe, 2021

Introduction: Two large multicentre European hospital networks have estimated vaccine effectiveness (VE) against COVID-19 since 2021. Aim: We aimed to measure VE against PCR-confirmed SARS-CoV-2 in hospitalised severe acute respiratory illness (SARI) patients≥20 years, combining data from these networks during Alpha (March–June)- and Delta (June–December)dominant periods, 2021. Methods: Forty-six

Distinct Intra- and Interspecific Foraging Patterns of Stingless Bee Species as a Conservation Tool

Stingless bees (Meliponini) are important pollinators in tropical ecosystems and very abundant in the Bolivian Yungas region; yet little is known about their foraging behavior and floral preferences. In this study, we combined melissopalynology, pollen analysis from honey, with plant-pollinator interactions network to investigate foraging behavior and niche overlap of three rescued stingless bee s

Molecular Dissection of Constans (CO) Homologs and Their Regulatory Role in Floral Induction of Mango (Mangifera indica L.)

Constans (CO), one of the key transcription factors of the zinc finger family, plays a crucial role in the photoperiodism-dependant flowering pathway. A systematic structural and functional analysis of the CO gene homologs need to be conducted in mango cultivars with contrasting bearing behaviors: ‘Amrapali’ (regular) and ‘Chausa’ (irregular). RNA-Seq leaf transcriptomes were mined for CO homologs

Improving equity in access to care: The impact of health insurance and family planning messages on access to maternal and reproductive health in Zambia

IntroductionEquitable access to maternal and reproductive health (MRH) services remains a major challenge in low- and lower-middle-income countries (LLMICs), including Zambia. Despite health system reforms such as the National Health Insurance Scheme (NHIS) and family planning (FP) communication strategies, disparities persist, particularly among socioeconomically disadvantaged populations. This t