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SPECT Imaging using Pinhole Collimation : System Design and Simulation Studies for Pre-Clinical and Clinical Imaging

Nuklearmedicinsk bildtagning med hjälp av radiofarmaka är ett viktigt verktyg för att studera biologiska processer och humansjukdomar. Bildtagning sker ofta med en detektor i kombination med en kollimator. En typ av kollimering är pinnhålskollimering, där ett pinnhål i ett opakt material placeras mellan en källa och en detektor. Pinnhålet fyller samma funktion som en optisk lins då emitterade fotoThe focus of this dissertation is the use of pinhole collimation in Nuclear Medicine. A pinhole is a single aperture in an opaque material that is placed between the detector and source of interest, and photons must pass through the hole to reach the detector. The choices of pinhole parameters, e.g. the pinhole material and size of the opening, are closely linked to the performance of the detector

Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT

P1 and Pk are glycosphingolipid antigens synthesized by the A4GALT-encoded α1,4-galactosyltransferase, using paragloboside and lactosylceramide as acceptor substrates, respectively. In addition to the compatibility aspects of these histo-blood group molecules, both constitute receptors for multiple microbes and toxins. Presence or absence of P1 antigen on erythrocytes determines the common P1 (P1+

Women, Power, and the Bible in Early Anabaptist History

The article argues that the way Anabaptist history and theology is commonly narrated needs to be reshaped. A fundamental question is asked: Did women have positions of power in the early Anabaptist movement? Two points are considered: 1) How is power understood? and 2) On what premises can the history of Anabaptist women be written? These two points are put in relation to portraits of three women

Spin and electronic structure of the topological insulator Bi1.5Sb0.5Te1.8Se1.2

Electronic and spin structure of the Dirac-cone-like topological surface and valence band states were studied experimentally and theoretically for topological insulator with fractional stoichiometry Bi1.5Sb0.5Te1.8Se1.2 which is considered as one of the best candidates for efficient spin-polarized current generation. By means of spin- and angle-resolved photoelectron spectroscopy we demonstrate th

Light and oxygen induce chain scission of conjugated polymers in solution

Conjugated polymers have been widely studied as flexible, versatile semiconductors in organic electronics. However, the material stability is one of the problems limiting their applications. Thus, understanding the degradation process of conjugated polymers is crucial. In this work, we monitored the chain scission of the model polymer MEH-PPV in chloroform solutions under different conditions by a

Faith and Hope in Situations of Epistemic Uncertainty

When it comes to religion, lack of conclusive evidence leads many reflective thinkers to embrace agnosticism. However, pure agnosticism does not necessarily have to be the final word; there are other attitudes one might reasonably adopt in a situation of epistemic uncertainty. This article concentrates on J. L. Schellenberg's proposal that non-doxastic propositional faith is available even when be

Coping, social support and information in patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension : A 2-year retrospective cohort study

Objectives: Pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension are severe diseases with complicated treatment that need care at specialist clinics. The aim was to investigate changes in the patients' perceptions on coping, social support and received information when attending a newly started nurse-coordinated pulmonary arterial hypertension-outpatient clinic.Methods

Typography serving ideology: typography of the Romanian newspapers before and after the communist takeover

Between the two world wars the typography of the Romanian newspapers followed the general development and the use of serif typefaces for the body type. The concern for the typography of the newspaper was rather conservative and worked a lot with the same kind of typography used for the fiction literature. After the communist take over in 1943 the typography of the newspapers followed the standards

Europe's lost forests : A pollen-based synthesis for the last 11,000 years

8000 years ago, prior to Neolithic agriculture, Europe was mostly a wooded continent. Since then, its forest cover has been progressively fragmented, so that today it covers less than half of Europe's land area, in many cases having been cleared to make way for fields and pasture-land. Establishing the origin of Europe's current, more open land-cover mosaic requires a long-term perspective, for wh