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Molecular Dynamic Studies of Transportan Interacting with a DPPC Lipid Bilayer

Translocation of peptides through cellular membranes is a fundamental problem in developing antimicrobial peptides and in drug delivery. There is a class of peptides, known as cell-penetrating peptides, that are able to penetrate membranes without disrupting them. They can carry pharmacological compounds, thus a promising strategy for drug delivery. The physical mechanisms that facilitate transloc

Performance of biofilm carriers in anaerobic digestion of sisal leaf waste leachate

Three methanogenic biofilm bioreactors were studied to evaluate the performance of three types of carriers. The carrier material were consisted of sisal fibre waste, pumice stone and porous glass beads, and the bioprocess evaluated was the methanogenesis anaerobic digestion of sisal leaf waste leachate. Process performance was investigated by increasing the organic loading rate (OLR) step-wise. Th

En etymologisk konspiration : långa och korta prepositioner

Several Swedish prepositions have two variants, established a few centuries ago. In some cases the long form is older, in other cases the short form is. The article discusses this as some form of conspiration leading to a situation where the long form tends to have partly other uses than the short form.

Tongue articulation of front close vowels in Stockholm, Gothenburg and Malmöhus Swedish

Articulatory data were collected for the Swedish vowels /iː, yˌ, ʉ̟ː/ from nine speakers each of Stockholm, Gothenburg, and Malmöhus Swedish, and the tongue positions and their dynamics analysed using Functional Data Analysis (FDA). Results showed that the general tongue positions for /iː/ and /yː/ are similar and clearly different from /ʉ̟ː/ in all three dialects. Variation within the Stockholm a

Nocturnal homing: learning walks in a wandering spider?

Homing by the nocturnal Namib Desert spider Leucorchestris arenicola (Araneae: Sparassidae) is comparable to homing in diurnal bees, wasps and ants in terms of path length and layout. The spiders' homing is based on vision but their basic navigational strategy is unclear. Diurnal homing insects use memorised views of their home in snapshot matching strategies. The insects learn the visual scenery

Non-Parametric Data-Dependent Estimation of Specroscopic Echo-Train Signals

This paper proposes a novel non-parametric estimator for spectroscopic echo-train signals, termed ETCAPA, to be used as a robust and reliable first-approach-technique for new, unknown, or partly disturbed substances. Exploiting the complete echo structure for the signal of interest, the method reliably estimates all parameters of interest, enabling initial estimates for the identification procedur

Erythroid urea transporter deficiency due to novel JK(null) alleles

BACKGROUND: The Kidd blood group antigens Jk(a) and Jk(b) are encoded by the red blood cell (RBC) urea transporter gene. Homozygosity for silent JK alleles results in the rare Jk(a-b-) phenotype. To date, seven JK(null) alleles have been identified, and of these, two are more frequent in the Polynesians and Finns. This study reports the identification of other JK(null) alleles in Jk(a-b-) individu

Using a Process of Collective Biography Writing in Higher Education fo Develop an Ability to Explore, Reveal and Critically Reflect

ABSTRACT Teaching and learning are frequently treated as processes that are separate from each other, while teachers and learners are considered as disembodied entities with a neutral position towards the content which is negotiated. In collective biography writing (CBW), a very different approach is taken. Writing, reading and learning are seen as an integrated whole, where teachers and educators

The risk of malignancy in unilocular cysts: a study on 1148 adnexal masses classified as unilocular cysts at transvaginal scan with review of the literature.

Objectives: To estimate the rate of malignancy in adnexal lesions described as unilocular cysts at transvaginal ultrasound examination, to investigate if there are differences in clinical and ultrasound characteristics between benign and malignant unilocular cysts. Methods: 3511 patients with an adnexal mass underwent transvaginal ultrasound examination between 1999 and 2007. The sonologists used

Size-varied photoelectron spectroscopy of metal clusters using the Exchange Metal Cluster Source

The recently developed Exchange Metal Cluster Source (EXMEC) is described. The source is designed for electron-spectroscopic studies of neutral metal clusters. Preliminary results on the rubidium and tin clusters using synchrotron radiation excited photoelectron spectroscopy show the capability for cluster production in the size regime of few tens to few hundred of atoms per cluster. A wide range

Structural Basis of Immune Receptor Binding by Staphylococcal Superantigens

Superantigens (SAgs) are toxins capable of inducing a massive immune response, leading to severe disease. They are secreted by the bacteria Staphylococcus aureus and Streptococcus pyogenes, which produce the staphylococcal enterotoxins and streptococcal pyogenic exotoxins, respectively. Our immune system has evolved to protect us against foreign threats, such as bacteria and viruses. By engulfing

Localized Deposition of Au Nanoparticles by Direct Electron Transfer through Cellobiose Dehydrogenase

Cellobiose dehydrogenase (CDH) is a fascinating extracellular fungal enzyme that consists of two domains, one carrying a flavin adenine dinucleotide (FAD) and the other a cytochrome-type heme b group as cofactors. The two domains are interconnected by a linker and electrons can shuttle from the FAD to the heme group by intramolecular electron transfer. Electron transfer between CDH and an electrod

Parametrized model reduction based on semidefinite programming

A parametrized model in addition to the control and state-space variables depends on time-independent design parameters, which essentially define a family of models. The goal of parametrized model reduction is to approximate this family of models. In this paper, a reduction method for linear time-invariant (LTI) parametrized models is presented, which constitutes the development of a recently prop

Line Topology Identification Using Multiobjective Evolutionary Computation

The broadband capacity of the twisted-pair lines strongly varies within the copper access network. It is therefore important to assess the ability of a digital subscriber line (DSL) to support the DSL services prior to deployment. This task is handled by the line qualification procedures, where the identification of the line topology is an important part. This paper presents a new method, denoted

Power and metabolic scope of bird flight: a phylogenetic analysis of biomechanical predictions

For flying animals aerodynamic theory predicts that mechanical power required to fly scales as P proportional, variant m (7/6) in a series of isometric birds, and that the flight metabolic scope (P/BMR; BMR is basal metabolic rate) scales as P (scope) proportional, variant m (5/12). I tested these predictions by using phylogenetic independent contrasts from a set of 20 bird species, where flight m

Gasoline Partially Premixed Combustion in a Light Duty Engine at Low Load and Idle Operating Conditions

Partially premixed combustion (PPC) has the potential of high efficiency and simultaneous low soot and NOx emissions. Running the engine in PPC mode with high octane number fuels has the advantage of a longer premix period of fuel and air which reduces soot emissions, even at higher loads. The problem is the ignitability at low load and idle operating conditions. The objective of this study is in

Molecular Motor Propelled Filaments Reveal Light-Guiding in Nanowire Arrays for Enhanced Biosensing

Semiconductor nanowire arrays offer significant potential for biosensing applications with optical read-out due to their high surface area and due to the unique optical properties of one-dimensional materials. A challenge for optical read-out of analyte-binding to the nanowires is the need to efficiently collect and detect light from a three-dimensional volume. Here we show that light from fluorop