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From an evolutionary point of view a pathogen might benefit from regulating the inflammatory response, both in order to facilitate establishment of colonization and to avoid life-threatening host manifestations, such as septic shock. In agreement with this notion Streptococcus pyogenes exploits type I IFN-signaling to limit detrimental inflammation in infected mice, but the host-pathogen interacti

Current evidence on congenital malformations in the offspring of cancer survivors is largely inconsistent. Therefore, through this study we aimed to explore the prevalence of congenital malformations in the offspring of cancer survivors. To this end, female cancer survivors were identified from the Swedish Cancer Register and were further linked to the Swedish Medical Birth Register and Hospital D

A search for long-lived, massive particles predicted by many theories beyond the Standard Model is presented. The search targets final states with large missing transverse momentum and at least one high-mass displaced vertex with five or more tracks, and uses 32.8 fb-1 of s=13 TeV pp collision data collected by the ATLAS detector at the LHC. The observed yield is consistent with the expected backg

A detailed fire investigation of most fires occurring in the greater London area has been underway since 1994. The present study concerns 307 fires in non-residential buildings there between 1994 and 1997. The cause of the fire, the means of discovery, the times to detection, to arrival of the fire brigade and to extinguishing the fire, the size of fire and the process of extinguishing it are inve

Margarine represents the pinnacle of culinary modernity, but it also has deep-seated working-class undertones connected to its origin as a butter substitute to feed the masses. This paper employs close readings as a tool to explore references to margarine in literary texts, and to situate them within a broader cultural context. In the first section of the analysis margarine references are surveyed

This is the first multi-district Standardised Patient (SP) study in South Africa. It measures the quality of TB screening at primary healthcare (PHC) facilities. We hypothesise that TB screening protocols and best practices are poorly adhered to at the PHC level. The SP method allows researchers to observe how healthcare providers identify, test and advise presumptive TB patients, and whether thisThis is the first multi-district Standardised Patient (SP) study in South Africa. It measures the quality of TB screening at primary healthcare (PHC) facilities. We hypothesise that TB screening protocols and best practices are poorly adhered to at the PHC level. The SP method allows researchers to observe how healthcare providers identify, test and advise presumptive TB patients, and whether this

Orglet er et af de musikinstrumenter, som stadig anvendes i dag, der er at finde længst tilbage i den vesteuropæiske musiktradition. Allerede i det 3. århundrede f.Kr. findes versioner af instrumentet hos grækerne, som med tiden blev så populære, at de blev et fast element under de romerske gladiatorkampe. I middelalderen flyttede orglet ind i kristne kirkerum, først som flytbare orgler og siden 1

Förord till Otto Carius självbiografi om de strider som han deltog i på östfronten under andra världskriget samt likheter och skillnader mellan hans och andra tyska veteraners krigsskildringar.

Beyond the esoteric deliberations of Islamic jurists and their exegesis of criminal and private law doctrines, Iranian law lives a life of its own. It is a life of routine practices of judges, court clerks, lawyers and clients, each of whom is striving to turn the law to their own advantage. It is also a life of contested legality, a relentless struggle over the right to determine the law in a jurBeyond the esoteric deliberations of Islamic jurists and their exegesis of criminal and private law doctrines, Iranian law lives a life of its own. It is a life of routine practices of judges, court clerks, lawyers and clients, each of whom is striving to turn the law to their own advantage. It is also a life of contested legality, a relentless struggle over the right to determine the law in a jur

In 66 CE, Marcia Servilia (PIR2 S 606) was summoned before the Senate to answer the accusation that she had paid magicians to conduct rites on her father’s behalf (Tac. Ann. 16.30–3; Dio Cass. 62.26.3; Marshall 1990, 363, case no. 24; Pollard 2014). Servilia and her father, who was accused of maiestas, made pleas before the Senate on each other’s behalf and in Tacitus’ narrative her illegal action

Purpose – The purpose of this paper is to study a class of issues that in spite of recognised needs and explicit managerial demands have proven hard to have “stick” in organisations (information security is used as an example). It offers a theory-driven rationale why superficially different issue areas can indeed be considered as instances of the identified class, and builds on complexity leadershPurposeThe purpose of this paper is to study a class of issues that in spite of recognised needs and explicit managerial demands have proven hard to have “stick” in organisations (information security is used as an example). It offers a theory-driven rationale why superficially different issue areas can indeed be considered as instances of the identified class, and builds on complexity leadership

Many firms manage the innovation process by using metrics. Yet, whether measurement supports or hinders innovation continues to be a topic of debate. To shed new light on this debate, this paper presents a conceptual framework of how measurement engages attention in firms. We draw on attention based theory and conceptualize innovation measurement as an attention-focusing device. We identify two id

Studies of relations binding ruled and ruler over the form and content of revenue assessment during the colonial era are not lacking. Rather, the intellectual challenge lies in ascertaining the degree to which the relevant economic institutions of the subjected regions in southern Asia constituted continuity of tradition, modifications thereof, or completely alien constructs. Meeting that challeng