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Self-Assembly of Model Amphiphilic Peptides in Nonaqueous Solvents : Changing the Driving Force for Aggregation Does Not Change the Fibril Structure

Within the homologous series of amphiphilic peptides AnK, both A8K and A10K self-assemble in water to form twisted ribbon fibrils with lengths around 100 nm. The structure of the fibrils can be described in terms of twisted β-sheets extending in the direction of the fibrils, laminated to give a constant cross section of 4 nm by 8 nm. The finite width of the twisted ribbons can be reasonably explai

Bayesian Method for Fuel Mass Estimation of Short Pilot Injections based on its Misfire Probability

A fuel mass estimation method for short pilot diesel injections is proposed and analyzed in this article. Previous studies showed that the pilot misfire ratio was more strongly correlated with the fuel mass than the on-time. This characteristic is exploited for the fuel mass estimation in a region where it is otherwise challenging to get good estimation accuracy due to the low signal-to-noise rati

Protective effect of intermediate doses of hydrogen sulfide against myocardial ischemia-reperfusion injury in obese type 2 diabetic rats

Objective: Subjects with type 2 diabetes (T2D) have lower circulating hydrogen sulfide (H2S) levels following myocardial ischemia and a higher risk of mortality. The aim of this study was to determine the dose-dependent favorable effects of sodium hydrosulfide (NaSH) on myocardial ischemia-reperfusion (IR) injury in rats with T2D. Methods: T2D was induced using a high-fat diet (HFD) and low-dose o

Desire to delay the first childbirth among young, married women in India : A cross-sectional study based on national survey data

Background: Young women in India continue to face diverse challenges that threaten their health and wellbeing. The reproductive health and rights of newly married women, who are often expected to begin childbearing soon after marriage, are often neglected. The present study aims to understand some of the factors associated with the desire to delay the first childbirth in young, married women in In

Analysis, Findings and Conclusions

n the Overview beginning Part II of this book, we discussed our selection of cases in relation to theory, concepts, and policies. We also discussed making analytical generalisations from a theoretically based sample of comparable cases. Now, after reviewing relevant theoretical, conceptual and policy issues in Part I of this book, and presenting a series of empirical case studies in Part II, we tu

Orthostatic Hypertension : Critical Appraisal of an Overlooked Condition

Orthostatic hypertension, which appears to be mediated through excess neurohumoral activation while standing, is a common blood pressure trait among patients with and without arterial hypertension. However, lack of consensus regarding the definition of orthostatic hypertension makes it difficult to assess the true prevalence of this condition. Orthostatic hypertension appears to predict the risk f

Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences

SUMMARY: Antibody repertoires reveal insights into the biology of the adaptive immune system and empower diagnostics and therapeutics. There are currently multiple tools available for the annotation of antibody sequences. All downstream analyses such as choosing lead drug candidates depend on the correct annotation of these sequences; however, a thorough comparison of the performance of these tool

Social democracy and the fate of the swedish model

Sweden attracted much attention as an interesting socioeconomic role model already in the 1930s, especially after Marquis Childs published his famous and influential book, The Swedish Middle Way (1936). Childs’ main argument was that the “Swedish model” was a successful “socialist” policy with a growing cooperative sector-as a counterbalance to the private sector-and effective crisis management. O

Characterizing of water-energy-emission nexus of coal-fired power industry using entropy weighting method

The coupled relationships among water, energy, and emission, i.e., water-energy-emission nexus (WEEN), are found to be spatial-temporally characterized. This research is aimed at evaluating the spatial-temporal characteristics of the WEEN of the selected 227 coal-fired power plants in China from 2012 to 2014 by employing the entropy weighting method. Firstly, the WEEN performances (the sub-indicat

Absence of ECG Task Force Criteria does not rule out structural changes in genotype positive ARVC patients

Aims: In Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC), electrophysiological pathology has been claimed to precede morphological and functional pathology. Accordingly, an ECG without ARVC markers should be rare in ARVC patients with pathology identified by cardiac imaging. We quantified the prevalence of ARVC patients with evidence of structural disease, yet without ECG Task Force Criteri

Best practices for cystometric evaluation of lower urinary tract function in muriform rodents

Aims: Rodent cystometry has provided valuable insights into the impact of the disease, injury, and aging on the cellular and molecular pathways, neurologic processes, and biomechanics of lower urinary tract function. The purpose of this white paper is to highlight the benefits and shortcomings of different experimental methods and strategies and to provide guidance on the proper interpretation of

Root-zone soil moisture variability across African savannas : From pulsed rainfall to land-cover switches

The main source of soil moisture variability in savanna ecosystems is pulsed rainfall. Rainfall pulsing impacts water-stress durations, soil moisture switching between wet-to-dry and dry-to-wet states, and soil moisture spectra as well as derived measures from it such as soil moisture memory. Rainfall pulsing is also responsible for rapid changes in grassland leaf area and concomitant changes in e

LES/PDF modeling of swirl-stabilized non-premixed methane/air flames with local extinction and re-ignition

Turbulent non-premixed flames with local extinction and re-ignition exhibit multiple combustion modes including ignition waves, diffusion flames, partially premixed flames, and ignition-assisted partially premixed flames. The mechanisms of local extinction and re-ignition are not well understood and numerical modeling of multi-mode combustion is a challenging task. In this work, a specially design

How can airborne transmission of COVID-19 indoors be minimised?

During the rapid rise in COVID-19 illnesses and deaths globally, and notwithstanding recommended precautions, questions are voiced about routes of transmission for this pandemic disease. Inhaling small airborne droplets is probable as a third route of infection, in addition to more widely recognized transmission via larger respiratory droplets and direct contact with infected people or contaminate