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Reproducibility of tryptic digestion investigated by quantitative fourier transform ion cyclotron resonance mass spectrometry

In this study, the reproducibility of tryptic digestion of complex solutions was investigated using liquid chromatography Fourier transform ion cyclotron resonance (LC FT-ICR) mass spectrometry. Tryptic peptides, from human cerebrospinal fluid, (CSF) were labeled with Quantification-Using-Enhanced-Signal-Tags (QUEST)-markers, or 1-([H-4]nicotinoyloxy)- and 1-([D-4]nicotinoyloxy)-succinimide ester

Human Capital and Economic Growth: Sweden 1870-2000

This paper presents newly constructed series on human capital in Sweden 1870–2000. The estimates are based on enrolment in different forms of education, stretching as far back as 1812, and the size and age distribution of the population within age range 15–65 years. The secular accumulation of human capital has closely matched the long-term trend in aggregate productivity and both grew at a rate o

Application of natural, social, and economical sustainability limitations to forest management, based on Swedish experiences

Abstract in UndeterminedWe suggest a method of analyzing the sustainability conditions for forestry from three major realms: environmental, social, and economic. The tools and methods were tested at sites in Sweden. Assessments were made for the long-term sustainability concerning the impact of present management practices on the balances of nutrients in monocultures and mixed-species stands. In t

Identification of a streptococcal octapeptide motif involved in acute rheumatic fever

Acute rheumatic fever is a serious autoimmune sequela of pharyngitis caused by certain group A streptococci. One mechanism applied by streptococcal strains capable of causing acute rheumatic fever is formation of an autoantigenic complex with human collagen IV. In some geographic regions with a high incidence of acute rheumatic fever pharyngeal carriage of group C and group G streptococci prevails

Selective cefuroxime prophylaxis following colorectal surgery based on intra-operative dipslide culture

The concept of a very limited effective period for prophylactic antibiotic action was challenged in a prospective, controlled and randomized study featuring a simplified method for assessing the degree of contamination in the operative field during colorectal surgery. The 226 patients were given 1 g metronidazole IV on induction of anaesthesia and 12 h postoperatively. Following standardized salin

Diameter and compliance in the human common carotid artery--variations with age and sex

In this study, age and sex differences in diameter and compliance of the common carotid artery (CCA) were evaluated in 119 healthy subjects with a phase-locked echo-tracking system. The diameter and pulsatile diameter changes were measured, and pressure strain elastic modulus (Ep) and stiffness (beta) were calculated and used as the inverse estimate of compliance. The carotid diameter increased mo

Distribution of alkaline sphingomyelinase activity in human beings and animals. Tissue and species differences

The alkaline sphingomyelinase (SMase) was first found in rat intestinal brush border. The important roles of this enzyme in digestion of sphingomyelin and in mucosal cell proliferation have been suggested. In the present work, the distribution of the alkaline SMase in the tissues of human beings and animals have been studied. By assaying the enzyme activity in human biopsy samples, we found that t

In Situ Observation of the Genesis of Mesoporous Silica SBA-15: Dynamics on Length Scales from 1 nm to 1 mum.

We report on the mechanism of growth of mesoporous silica (SBA-15, plane group p6m). In situ studies of the formation using ultrasmall angle X-ray scattering (USAXS) and small-angle X-ray scattering (SAXS) covering length scales from 5 to 10 000 A, complemented with UV-vis and transmission electron microscopy (TEM), provide unique data on particle growth coupled with information regarding the prog

The proteoglycan lectin domain binds sulfated cell surface glycolipids and promotes cell adhesion

The lecticans are a group of chondroitin sulfate proteoglycans characterized by the presence of C-type lectin domains. Despite the suggestion that their lectin domains interact with carbohydrate ligands, the identity of such ligands has not been elucidated. We previously showed that brevican, a nervous system-specific lectican, binds the surface of B28 glial cells (Yamada, H., Fredette, B., Shitar

What happens with the dizzy patient in primary health care? Does education influence treatment?

Dizziness is a common symptom, and recent research shows that physical activity and specific treatment of vertigo and dizziness are effective. The management of dizzy patients requires assessment and, when appropriate, treatment by a physiotherapist. We have therefore studied how general practitioners (GPs) handle patients with vertigo and dizziness, to find out whether treatment follows current r

Spin States of holes in ge/si nanowire quantum dots.

We investigate tunable hole quantum dots defined by surface gating Ge/Si core-shell nanowire heterostructures. In single level Coulomb-blockade transport measurements at low temperatures spin doublets are found, which become sequentially filled by holes. Magnetotransport measurements allow us to extract a g factor g;{*} approximately 2 close to the value of a free spin-1/2 particle in the case of

Effects of liming on the uptake of organic and inorganic nitrogen by mycorrhizal (Paxillus involutus) and non-mycorrhizal Pinus sylvestris plants

Seedlings of Pinus sylvestris L. were grown in Plexiglas(R) observation chambers in limed (CaCO3, pH 5.0 and 5.9) and untreated (pH 4.1) peat. The seedlings were either colonized by the mycorrhizal fungus Paxillus involutus (Batsch: Fr.) Fr. Or were non-mycorrhizal. After 18 wk in the observation chambers, N-15-labelled organic nitrogen, as lyophilized and ground mycelium of Suillus variegatus (Sw

Modelling geochemistry and Lake pH since glaciation at Lake Gårdsjön

The soil acidification model SAFE was modified to calculate historical changes in geochemistry and runoff since the last glaciation ended at the Lake Gårdsjön F1 catchment 12 000 B.P. Changes in runoff pH and ANC, soil weathering rate, soil mineralogy, soil texture and base saturation was also calculated. The changes in mineralogy compared favorable to data. Modeled historic weathering rates were

Additive and non-additive genetic architecture of two different-sized populations of Scabiosa canescens

Future adaptation to changes in the environment depends on the existence of additive genetic variances within populations. Recently, considerable attention has also been given to the non-additive component, which plays an important role in inbreeding depression and bottleneck situations. In this study, I used data from a North Carolina II crossing experiment, analysed with restricted maximum-likel

Adsorption and Activity of Trichoderma reesei Cellobiohydrolase I, Endoglucanase II, and the Corresponding Core Proteins on Steam Pretreated Willow

The adsorption and the hydrolytic action of purified cellulases of Trichoderma reesei, namely, cellobiohydrolase I (CBH I), endoglucanase II (EG II), and their core proteins, on steam-pretreated willow were compared. The two enzymes differed clearly in their adsorption and hydrolytic behavior. CBH I required the cellulose-binding domain (CBD) for efficient adsorption and hydrolysis, whereas EG II