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A whole blood approach improves speed and accuracy when measuring mitochondrial respiration in intact avian blood cells

Understanding mitochondrial biology and pathology is key to understanding the evolution of animal form and function. However, mitochondrial measurement often involves invasive, or even terminal, sampling, which can be difficult to reconcile in wild models or longitudinal studies. Non-mammal vertebrates contain mitochondria in their red blood cells, which can be exploited for minimally invasive mit

Plasticity of mitochondrial function safeguards phosphorylating respiration during in vitro simulation of rest-phase hypothermia

Many animals downregulate body temperature to save energy when resting (rest-phase hypothermia). Small birds that winter at high latitudes have comparatively limited capacity for hypothermia and so pay large energy costs for thermoregulation during cold nights. Available evidence suggests this process is fueled by adenosine triphosphate (ATP)-dependent mechanisms. Most ATP is produced by oxidative

Genetic Susceptibility to Mood Disorders and Risk of Stroke : A Polygenic Risk Score and Mendelian Randomization Study

BACKGROUND: Mood disorders and strokes are often comorbid, and their health toll worldwide is huge. This study characterizes prognostic and causal roles of mood disorders in stroke.METHODS: We tested if genetic susceptibilities for mood disorders were associated with all strokes, ischemic strokes in the Malmö Diet and Cancer cohort (24 631 individuals with a median follow-up of 21.3 (interquartile

Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria : VmlR2, Ard1 and CplR

Genome-encoded antibiotic resistance (ARE) ATP-binding cassette (ABC) proteins of the F subfamily (ARE-ABCFs) mediate intrinsic resistance in diverse Gram-positive bacteria. The diversity of chromosomally-encoded ARE-ABCFs is far from being fully experimentally explored. Here we characterise phylogenetically diverse genome-encoded ABCFs from Actinomycetia (Ard1 from Streptomyces capreolus, produce

Studying amount, location and state of water in modified wood at moisture levels relevant for fungal degradation

Water is an essential parameter for fungal degradation of wood, but degradation primarily occursat high moisture levels at water potential in the range of -4 to -0.1 MPa, which corresponds to 97-99.9% relative humidity. At these moisture levels, water is present in the wood structure both inand outside of cell walls. The majority of previous studies on the interaction between wood andwater for unt

Gentiles and Their Relations to Jews

The relations between Gentiles and Jews in the Greco-Roman world generally appear to have been characterized by relative harmony. Although reciprocal stereotyping, hostility, and prejudice indeed existed among Jews and Gentiles, there is also ample evidence of positive Gentile-Jewish social interaction, at least within some strata of the population. This most likely took place in the context of va

On the amplitude of steady water waves with positive constant vorticity

For two-dimensional steady pure-gravity water waves with a unidirectional flow of constant favourable vorticity, we prove an explicit bound on the amplitude of the wave, which decays to zero as the vorticity tends to infinity. Notably, our result holds true for arbitrary water waves, that is, we do not have to restrict ourselves to periodic or solitary or symmetric waves.

Symmetric doubly periodic gravity-capillary waves with small vorticity

We construct small amplitude gravity-capillary water waves with small nonzero vorticity, in three spatial dimensions, bifurcating from uniform flows. The waves are symmetric, and periodic in both horizontal coordinates. The proof is inspired by Lortz' construction of magnetohydrostatic equilibria in reflection-symmetric toroidal domains. It relies on a representation of the vorticity as the cross

Large-amplitude steady gravity water waves with general vorticity and critical layers

We consider two-dimensional steady periodic gravity waves on water of finite depth with a prescribed but arbitrary vorticity distribution. The water surface is allowed to be overhanging and no assumptions regarding the absence of stagnation points and critical layers are made. Using conformal mappings and a new Babenko-type reformulation of Bernoulli's equation, we uncover an equivalent formulatio

A scenario analysis of the potential effects of decarbonization on the profitability of the energy-intensive and natural-resource-based industries

The decarbonization of the energy-intensive and natural-resourced-based industries is associated with potentially large economic costs. In this paper, I explore how decarbonization may affect the profitability and market value of these industries. I also discuss the possibility of compensating for the investment costs through higher prices and enhanced productivity. I answer these questions using The decarbonization of the energy-intensive and natural-resourced-based industries is associated with potentially large economic costs. In this paper, I explore how decarbonization may affect the profitability and market value of these industries. I also discuss the possibility of compensating for the investment costs through higher prices and enhanced productivity. I answer these questions using

The problem of stagflation. How should the ECB respond to the increase in inflation?

Inflation began to increase rapidly towards the end of 2021 and remained elevated throughout 2022. Higher energy prices contributed significantly to the increase in inflation. However, core-inflation, excluding the direct contribution of energy prices, was also significantly above the European Central Bank’s inflation target. Partially due to the highly expansionary monetary policy during the pandInflation began to increase rapidly all around the world towards the end of 2021, and it remained elevated throughout 2022. Higher energy prices contributed significantly to the increase in inflation. However, core inflation, excluding the direct contribution of energy prices, was also significantly above the European Central Bank’s inflation target, which was partially due to the highly expansion

Inflation illiteracy - a micro-data analysis

Survey data Economic Tendency Survey Swedish households' perceptions of the current rate of inflation and their expectations of the future rate of inflation. They analyse what percentage of households can be considered to be poorly informed about inflation (as their responses devia on te significantly from the historical pattern of inflation), and what characterises these householdsUsing micro-level survey data from the National Institute of EconomicResearch’s Economic Tendency Survey, we find that a relatively largeshare of Swedish households is ill-informed about the rate of inflation inthe economy, with perceived and expected rates of inflation deviatingsubstantially from official measures. Probit analysis of the data indicatesthat such inflation illiteracy is related to

Shelley : Selected Poems

Percy Bysshe Shelley (1792 - 1822) was one of the major Romantic Poets and wrote what is critically recognised as some of the finest lyric poetry in the English Language. In this volume, the editors have selected the most popular, significant and frequently taught poems from the 6-volume Longman Annotated edition of Shelley's poems. Each poem is fully annotated, explained and contextualised, along

Co-creating injury prevention training for youth handball players targeting end-users at the individual, team and organizational levels

IntroductionInjury prevention training is effective in reducing injuries in youth team sports, but public health impact is limited because such training is not widely, properly, or sustainably implemented. Insufficient involvement of end-users has been identified as a main barrier to implementation. Based on results from previous studies within the I-PROTECT project, the aim was to develop a full

Global area boom for greenhouse cultivation revealed by satellite mapping

Greenhouse cultivation has been expanding rapidly in recent years, yet little knowledge exists on its global extent and expansion. Using commercial and freely available satellite data combined with artificial intelligence techniques, we present a global assessment of greenhouse cultivation coverage and map 1.3 million hectares of greenhouse infrastructures in 2019, a much larger extent than previo

MEASUREMENTS OF THE REACTION CROSS SECTIONS OF NEUTRON-RICH Sn ISOTOPES AT THE R3B SETUP

A fundamental framework to describe nuclear matter as a function of pressure and nuclear isospin asymmetry is the nuclear Equation of State (EoS). Constraining the parameters of the EoS is one of the central issues in nuclear physics, especially since the slope parameter L has not yet been constrained well experimentally. It has been identified that a precise determination of the neutron-removal c

We Overfeed Our Heroes Until They Explode. A public artwork forty years in the making

Text discussing the 40-year history of the artwork We Overfeed Our Heroes Until They Explode. Originally created as an unsanctioned stencil painting by American artists John Fekner and Don Leicht in Lund, Sweden, in 1984, the work was recently revisited by Fekner together with American artist Brad Downey as part of a commissioned art project for LundART. A central point raised in the text is the d

Multi-objective Optimization and GIS to Improve Climate Change Induced Disaster Risk Management in Africa

We live in an era that suffers from climate change issues, not least disaster risks induced by climate change. While measures, such as proper evacuation plans, are required to reduce the negative impacts of disasters when they hit, actions should also be taken to reduce climate change effects by e.g. increasing the use of renewable energies or proper urban land-use allocation, where climate change