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Early and long-term prognosis in patients with and without type 2 diabetes after carotid intervention : a Swedish nationwide propensity score matched cohort study

Objectives: To investigate early and long-term outcomes after treatment of carotid artery stenosis in patients with type 2 diabetes (T2D) compared to patients without T2D. Design/method: This observational nationwide population-based retrospective cohort study investigated all T2D patients treated for carotid stenosis registered in the National Swedish Vascular Surgery and the National Diabetes Re

Ambipolar Behavior of Ge-Intercalated Graphene : Interfacial Dynamics and Possible Applications

For the realization of graphene-based electronic and optic devices, the functionalization of this material becomes essential. Graphene doping through intercalation and tuning the chemical potential is one among other promising concepts. Intercalation of germanium is particularly interesting in view of its ambipolar doping behavior. Both p- and n-type doped graphene and their doping levels were ide

Update of clothing database for existing and new Western clothing ensembles, including effects of posture, body and air movement : Report on manikin measurements for ASHRAE 1760-TRP.

ASHRAE Research Project RP-1760 aimed to update thedatabase of western clothing as used in ANSI/ASHRAE Stan-dard 55-2013, Thermal Environmental Conditions for HumanOccupancy (ASHRAE 2013a), ISO Standard 7730-2005,Ergonomics of the Thermal Environment—Analytical Deter-mination and Interpretation of Thermal Comfort Using Calcu-lation of the PMV and PPD Indices and Local ThermalComfort Criteria (ISO

Stochastic modelling of 3D fiber structures imaged with X-ray microtomography

Many products incorporate into their design fibrous material with particular levels of permeability as a way to control the retention and flow of liquid. The production and experimental testing of these materials can be expensive and time consuming, particularly if it needs to be optimised to a desired level of absorbency. We consider a parametric virtual fiber model as a replacement for the real

Continuum scale modelling and complementary experimentation of solid oxide cells

Solid oxide cells are an exciting technology for energy conversion. Fuel cells, based on solid oxide technology, convert hydrogen or hydrogen-rich fuels into electrical energy, with potential applications in stationary power generation. Conversely, solid oxide electrolysers convert electricity into chemical energy, thereby offering the potential to store energy from transient resources, such as wi

Climate-driven losses to Indigenous and local knowledge and cultural heritage

Anthropogenic climate change is leading to widespread losses around the world. While the focus of research over the last decade has largely been on economic or tangible losses, researchers have begun to shift their focus to understanding the non-economic or intangible dimensions of loss more deeply. Loss of life, biodiversity and social cohesion are some of the losses that are beginning to be expl

A high-throughput DNA extraction method for barley seed

A non-destructive, quick DNA extraction method for barley seed is described. The method is simple and consists of drilling out a sample from the seed, adding sodium hydroxide, heating in a microwave oven and neutralizing with Tris-HCl. The seed DNA extract can be used directly for PCR with extra cycles added to the PCR programme compared to PCR programmes used for leaf extracts. This protocol was

Resolving the age of the Puchezh-Katunki impact structure (Russia) against alteration and inherited 40Ar* – No link with extinctions

The possibility of a “death from above” cause for biotic crises and extinction events is intriguing, to say the least, but such claims must be supported by reliable and reproducible data, not only impact diagnostic criteria, but also accurate and precise radioisotopic ages of the impact structures/events. To date, only one example of such an impact-related global extinction event is confirmed, at

Clustering-based particle detection method for digital holography to detect the three-dimensional location and in-plane size of particles

Digital holography (DH) has been extensively applied in particle field measurements due to its promising ability to simultaneously provide the three-dimensional location and in-plane size of particles. Particle detection methods are crucial in hologram data processing to determine particle size and particle in-focus depth, which directly affect the measurement accuracy and robustness of DH. In thi

Sadness and other health complaints among Swedish adolescents : A cross-sectional study

Health complaints are increasing among adolescents and are recognized as a global public health issue. Health complaints are an indicator for subjective ill-being, but little is known about the relationship between sadness and other health complaints. The aim of this study was to investigate sadness and other health complaints among Swedish adolescents. A survey with a cross-sectional design was c

Open source languages and methods for cyber-physical system development : Overview and case studies

Industrial cyber-physical system products interleave hardware, software, and communication components. System complexity is increasing simultaneously with increased demands on quality and shortened time-to-market. To effectively support the development of such systems, we present languages and tools for comprehensive integrated model-based development that cover major phases such as requirement an

Analysis of Brain Injury Biomarker Neurofilament Light and Neurodevelopmental Outcomes and Retinopathy of Prematurity among Preterm Infants

Importance: Circulating levels of neurofilament light (NfL) and glial fibrillary acidic protein (GFAP) are important in the course of brain injury in adults, but longitudinal postnatal circulating levels in preterm infants have not been investigated. Objectives: To examine postnatal longitudinal serum levels of NfL and GFAP in preterm infants during the first 15 weeks of life and to explore possib

Synchronizing gas injections and time-resolved data acquisition for perturbation-enhanced APXPS experiments

An experimental approach is described in which well-defined perturbations of the gas feed into an Ambient Pressure X-ray Photoelectron Spectroscopy (APXPS) cell are fully synchronized with the time-resolved x-ray photoelectron spectroscopy data acquisition. These experiments unlock new possibilities for investigating the properties of materials and chemical reactions mediated by their surfaces, su

Ghost QTL and hotspots in experimental crosses : novel approach for modeling polygenic effects

Ghost quantitative trait loci (QTL) are the false discoveries in QTL mapping, that arise due to the "accumulation" of the polygenic effects, uniformly distributed over the genome. The locations on the chromosome that are strongly correlated with the total of the polygenic effects depend on a specific sample correlation structure determined by the genotypes at all loci. The problem is particularly

SAXS/WAXS Investigation of Amyloid-β(16-22) Peptide Nanotubes

This brief report presents an X-ray scattering investigation of self-assembled nanotubes formed by a short peptide. X-ray scattering methods enable multiscale structural elucidation of these nanotubes in solution under the same conditions involved in the self-assembly process. In particular, the dimensions of nanotubes and the crystalline organization within their walls can be determined quantitat

Lupin Protein Isolate Structure Diversity in Frozen-Cast Foams : Effects of Transglutaminases and Edible Fats

This study addresses an innovative approach to generate aerated foods with appealing texture through the utilization of lupin protein isolate (LPI) in combination with edible fats. We show the impact of transglutaminases (TGs; SB6 and commercial), glycerol (Gly), soy lecithin (Lec) and linoleic acid (LA) on the micro- and nanostructure of health promoting solid foods created from LPI and fats blen

PARP10 Multi-Site Auto- and Histone MARylation Visualized by Acid-Urea Gel Electrophoresis

Poly-ADP-ribose polymerase (PARP)-family ADP-ribosyltransferases function in various signaling pathways, predominantly in the nucleus and cytosol. Although PARP inhibitors are in clinical practice for cancer therapy, the enzymatic activities of individual PARP family members are yet insufficiently understood. We studied PARP10, a mono-ADP-ribosyltransferase and potential drug target. Using acid-ur

Hypoxia-Induced Reactivity of Tumor-Associated Astrocytes Affects Glioma Cell Properties

Glioblastoma is characterized by extensive necrotic areas with surrounding hypoxia. The cancer cell response to hypoxia in these areas is well-described; it involves a metabolic shift and an increase in stem cell-like characteristics. Less is known about the hypoxic response of tumor-associated astrocytes, a major component of the glioma tumor microenvironment. Here, we used primary human astrocyt