Ecdysteroids are critically important for formation of the insect exoskeleton. Cholesterol is a precursor of ecdysone and its active form 20-hydroxyecdysone, but some steps in the ecdysteroid biosynthesis pathway remain unknown. An essential requirement of glutathione transferase GSTE14 in ecdysteroid biosynthesis has been established in Drosophila melanogaster, but its function is entirely unknow

Human communication can be either monosemiotic or polysemiotic, depending on whether it combines ensembles of representations from one or more semiotic systems such as language, gesture and depiction. Each semiotic system has its unique storytelling potentials, which makes intersemiotic translation from one system to another challenging. We investigated the influence of the source semiotic system,

Peptide self-assembly is a spontaneous process, ubiquitous in nature for the creation of highly ordered and complex biological structures, making it a sought after technique in the development of novel biocompatible materials. The process is also strongly associated with various neurodegenerative diseases in the formation of amyloid plaques in diseases such as Alzheimer’s and Parkinson’s, where fu

Levodopa is a precursor to dopamine that has been shown to improve functional recovery following stroke partly achieved through mechanisms of brain plasticity. This study investigates if dopamine might affect plasticity by having a direct effect on synaptic plasticity through alterations in neurotransmitter release and re-uptake. Synaptogyrin is a synaptic vesicle protein that has been suggested t

The Xenopus oocyte and the Human Embryonic Kidney (HEK) 293 cell expression systems are frequently used for functional characterization (deorphanization) of insect odorant receptors (ORs). However, the inherent characteristics of these heterologous systems differ in several aspects, which raises the question of whether the two systems provide comparable results, and how well the results correspond

This article investigates the relation between subjective evaluations and objective measurements of daylighting in multi-family residential buildings. More specifically, the suitability of an observer-based environmental assessment (OBEA) instrument to assess indoor daylight conditions was tested in a field study conducted in six typical multi-family apartment buildings in the central and metropol

Introduction: Direct oral anticoagulants (DOACs) have been proven non-inferior or superior to warfarin in preventing stroke and systemic embolism, with a lower risk of major hemorrhage, in patients with non-valvular atrial fibrillation (NVAF). We sought to investigate whether effectiveness and safety differs among apixaban, rivaroxaban and dabigatran. Materials and methods: Patients with newly ini

Background: Endocrine disrupting chemicals (EDCs) are xenobiotics with the ability to interfere with hormone action, even at low levels. Prior environmental epidemiology studies link numerous suspected EDCs, including phthalates and bisphenol A (BPA), to adverse neurodevelopmental outcomes. However, results for some chemicals were inconsistent and most assessed one chemical at a time. Objectives:

With this special issue Seismograf introduce you to ten new audio papers developed for the journal. The 10 audio papers are published in two volumes: The first, #22 Sonic Argumentation I, gathers scholars from artistic research in music, and the second, #23 Sonic Argumentation II, presents papers by scholars from ethnography, literature and sound studies.

Background: Off-target [18F]flortaucipir (tau) PET binding in the choroid plexus causes spill-in into the nearby hippocampus, which may influence the correlation between [18F]flortaucipir binding and measures of cognition. Previously, we showed that partial volume correction (combination of Van Cittert iterative deconvolution and HYPR denoising; PVC HDH) and manually eroding the hippocampus result

With this special issue Seismograf introduces you to ten new audio papers developed for the journal. The 10 audio papers are published in two volumes: The first, #22 Sonic Argumentation I, gathers scholars from artistic research in music, and the second, #23 Sonic Argumentation II, presents papers by scholars from ethnography, literature and sound studies.

With this special issue we are delighted to introduce you to ten new audio papers developed for Seismograf. The 10 audio papers are published in two volumes: The first, #22 Sonic Argumentation I, gathers scholars from artistic research in music, and the second, #23 Sonic Argumentation II, presents papers by scholars from ethnography, literature and sound studies.

Modern emerging technologies, such as additive manufacturing, bioprinting, and new material production, require novel metrology tools to probe fundamental high-speed dynamics happening in such systems. Here we demonstrate the application of the megahertz (MHz) European X-ray Free-Electron Laser (EuXFEL) to image the fast stochastic processes induced by a laser on water-filled capillaries with micr

The new European X-ray Free-Electron Laser (European XFEL) is the first X-ray free-electron laser capable of delivering intense X-ray pulses with a megahertz interpulse spacing in a wavelength range suitable for atomic resolution structure determination. An outstanding but crucial question is whether the use of a pulse repetition rate nearly four orders of magnitude higher than previously possible

Vi bör hålla fast vid dagens överskottsmål ett tag till. Först när vi kommit ned till 25 procents offentlig skuld kan vi våga överge överskottsmålet, skriver ekonomerna Fredrik N G Andersson och Lars Jonung, Lunds universitet.