Understanding consciousness is central to understanding human nature. We have competing theories of consciousness. In interdisciplinary consciousness studies most believe that consciousness can be naturalized (i.e., consciousness depends in some substantial way on processes in — or states of — the brain). For roughly two decades, proponents of almost every theory have focused on collecting empiric

Introduction: Primary prophylaxis is the gold standard in severe haemophilia A (SHA) but time to escalate the prophylaxis regimen varies. Aim: Assess prophylaxis implementation and long-term joint health outcomes in SHA with primary prophylaxis. Methods: Adult male patients born after 1980, with SHA on primary prophylaxis, started before the age of 3 years and second joint bleed, and no history of

Acoustic testing is crucial in the aero-engine design process, providing valuable information about the sound field in terms of acoustic modes. The conventional use of a uniform sampling array limits the achievable resolution for a given number of sensors, necessitating the use of a large number of sensors to achieve high-resolution estimates. This limitation may be overcome using a non-uniform se

Background: Patients with cardiac implantable electronic device (CIED) and Staphylococcus aureus bacteraemia (SAB) are at risk of having CIED infection, pocket infection or endocarditis. To avoid treatment failures, guidelines recommend that the CIED should be extracted in all cases of SAB butrecent studies indicate low extraction rates and low risk of relapse. The aim of the study was to describe

Background: Multiple sclerosis (MS) is the most common chronic demyelinating disease of the central nervous system and the major non-traumatic cause of permanent disability in young adults. Several migration studies have been performed over the years suggesting a pattern of higher disease disability in certain ethnic groups. To our knowledge, differences in disease progression in immigrants have n

This work investigates the effects of atmospheric-pressure nanosecond (ns) pulsed plasma discharges on NH3/air flames using optical emission spectroscopy (OES). Firstly, spatially-resolved OES in the 200–800 nm range of NH3/air flames with and without discharges are presented to identify the plasma-induced excited species (such as N2* and H*). Then, time-resolved OES with ns timescale resolution a

Background: In chronic pulmonary diseases characterized by inflammation and airway obstruction, such as asthma and COPD, there are unmet needs for improved treatment. Quinolines is a group of small heterocyclic compounds that have a broad range of pharmacological properties. Here, we investigated the airway relaxant and anti-inflammatory properties of a novel quinoline (RCD405). Methods: The airwa

When new general-purpose technologies like AI emerge, both techno-optimists and techno-pessimists predict that inequality will increase among the labour force. This column studies the rapid introduction of electricity in early 20th century Sweden and its effect on workers. The transformative technology benefitted those at the bottom of the income distribution, resulting in higher incomes, lower in

Based on our previous study, we evaluated the modulatory effects on LPS-induced IL-1β and IL-10 cytokine production in RAW 264.7 macrophages of several medicinal herbs, including P. scandens. The results showed that P. scandens extract showed significant effects on LPS-induced IL-1β and IL-10 cytokine production in RAW 264.7 macrophages. Therefore, in the current research, we focused on the P. sca

Conservation and consistency are fundamental properties of discretizations of conservation laws, necessary to ensure physically meaningful solutions. In the context of systems of nonlinear hyperbolic conservation laws, conservation and consistency additionally play an important role in convergence theory via the Lax-Wendroff theorem. Here, these concepts are extended to the realm of iterative meth

BackgroundThe geometrical relationship between atrial and ventricular short‐axis cross‐sectional area determines the hydraulic forces acting on intracardiac blood. This is important for diastolic filling. In patients undergoing heart transplantation (HTx), the left atrium is often enlarged as a result of the standard surgical technique. We hypothesized that diastolic filling in HTx patients is aff

In this study, the partitioning of minerals in ultrafiltration (UF) streams of skim milk using cross-flow (CF-UF) and dead-end (DE-UF) was investigated using 50 kDa membrane at different temperatures (5, 10, 25, 35, 55°C). CF-UF showed higher protein retention (6.02–10.9%) compared with DE-UF (3.44–4.70%), along with more retention of calcium, with values ranging from 29.8 to 41.5 and 57.8 to 112

Purpose: The postponement principle concerns defining when and where value is added, usually referring to hardware components for physical products. However, in modern supply chains, software’s importance is increasing, impacting the timing and location of value-adding operations. Lacking insights into software-driven implications for postponement, we aim at elaborating on the postponement princip

Lipid-based drug delivery systems offer the potential to enhance bioavailability, reduce dosing frequency, and improve patient adherence. In aqueous environment, initially dry lipid depots take up water and form liquid crystalline phases. Variation of lipid composition, depot size and hydration-induced phase transitions will plausibly affect the diffusion in and out of the depot. Lipid depots of s

The social sciences have many different understandings of ‘normative power’, but in European Union (EU) studies normative power has three particular meanings. The first meaning of normative power is its emphasis on normative theory, that is, how we judge and justify truth claims in social science. The second meaning of normative power is as a form of power that is ideational rather than material o

Abstract in SpanishEn este artículo se propone un acercamiento didáctico a la enseñanza del Pretérito Perfecto Compuesto (PPC) en contextos de español como lengua extranjera. Se analizan algunos problemas de la visión tradicional sobre el tema y se plantea que el concepto de referencia genérica propuesto en Henderson (2010) da una respuesta más coherente a usos que la bibliografía suele adjudicar This article proposes a didactic approach to teaching the compound past tense that is known in English as “Present Perfect” (PPC for its initials in Spanish) in contexts of Spanish as a Foreign Language. It analyses some issues concerning the traditional view on the subject and suggests that the concept of generic reference proposed by Henderson (2010) provides a more coherent explanation for some

The idea of being civilian, military, and civilizing at the same time is undoubtedly very seductive to the armies of academics now writing on EU military force. It is tempting to think that the EU can have-its-cake-and-eat-it-too in militarizing its normative power. In contrast, in my reconsideration of normative power Europe I suggest that militarization of the EU need not necessarily lead to the