Convolutional Neural Networks (CNNs) have been subject to extensive attention in the pattern recognition literature due to unprecedented performance in tasks of information extraction from unstructured data. Whereas available methods for supervised training of a CNN with a given network topology are well-defined with rigorous theoretical justification, procedures for the initial selection of topol

Venous needle dislodgement (VND) during dialysis is a rarely occurring adverse event, which becomes life-threatening if not handled promptly. Because the standard venous pressure alarm, implemented in most dialysis machines, has low sensitivity, a novel approach using extracted cardiac information to detect needle dislodgement is proposed. Four features are extracted from the arterial and venous p

This study investigates the potential for Electrical Resistivity Tomography (ERT) to detect buried glass ‘hotspots’ in a glass waste dump based on results from an open glass dump investigated initially. This detection potential is vital for excavation and later use of buried materials as secondary resources. After ERT, test pits (TPs) were excavated around suspected glass hotspots and physico-chem

PURPOSE: The presence of neovascular age-related macular degeneration (nAMD) in one eye is a major risk factor for the development of disease in the fellow eye. Several methods exist to help physicians monitor the fellow eye, with new technologies becoming increasingly available. METHODS: We provide an overview of modalities for nAMD monitoring, including advances in home-based options, and review

Efficient and sustainable mobility is becoming a need for emerging metropolitan areas, essential to grant their attractiveness, quality of life and economic power. Among the possible strategies to adopt, shared mobility systems have proven to be a valuable alternative to accommodate the mobility needs of citizens ensuring at the same time sustainability and transport flexibility. In particular, th

Widening income and knowledge inqualities have led to growing expectations for universities to integrate social innovation in their core missions as a response to societal problems.This systematic review of literatureprovides an overview of the state-of-the-art of knowledge on the role of the university in enabling social innovation through its missions of teaching, research and third mission. It

Introduction Compression neuropathies (CN) in the upper extremity, the most common being carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE), are frequent among patients with diabetes mellitus (DM). Earlier studies have shown contradicting results regarding DM as a risk factor for CN. Thus, the aim of the present population-based, longitudinal study was to explore potential associations

Developing countries are giving increasing attention to industry development in renewable energy industries. Previous research highlights the influence of technology characteristics on such catching-up policies, distinguishing between complex products produced in small batches, and mass-produced simple products. We suggest that catching-up policies should move beyond this binary distinction betwee

Aim: Polypharmacy is becoming a global health problem. The aims of this study were to evaluate the temporal trends in the prevalence of polypharmacy in Sweden and to explore polypharmacy disparities by age, gender, education, and immigration status. Methods: Polypharmacy and excessive polypharmacy were evaluated using data extracted from the Swedish Prescribed Drug Register between 2006 and 2014.

Adopting a voluntary simplicity lifestyle (VSL) contributes to a change in consumption patterns towards more sustainable ones, which is urgently needed. This study defines the VSL as a voluntary reduction of income and consumption in exchange for more free time. Our research aims to contribute with more detailed VSL criteria. A literature review develops initial VSL criteria, which are validated a

Ichthyoses are a clinically and genetically heterogeneous group of genodermatoses associated with abnormal scaling of the skin over the whole body. Mutations in nine genes are known to cause non-syndromic forms of autosomal-recessive congenital ichthyosis (ARCI). However, not all genetic causes for ARCI have been discovered to date. Using whole-exome sequencing (WES) and multigene panel screening,

Background: Medication errors occur frequently at transitions in care and can result in morbidity and mortality. Medication reconciliation is a recognized hospital accreditation requirement and designed to limit errors in transitions in care. Objectives: To identify beliefs, perceived roles and responsibilities of physicians, pharmacists and nurses prior to the implementation of a standardized med

Here we describe the use of an organotypic hippocampal slice model for studying α-synuclein aggregation and inter-neuronal spreading initiated by microinjection of pre-formed α-synuclein fibrils (PFFs). PFF injection at dentate gyrus (DG) templates the formation of endogenous α-synuclein aggregates in axons and cell bodies of this region that spread to CA3 and CA1 regions. Aggregates are insoluble

The PHENIX experiment has studied nuclear effects in p+Al and p+Au collisions at sNN=200GeV on charged hadron production at forward rapidity (1.4

In a future climate change perspective, the interactions among different life-forms of primary producers will likely be altered, leading to changes in the relative dominance among macrophytes, filamentous, and planktonic algae. In order to improve the possibilities to forecast future ecosystem services and function, we therefore conducted a long-term mesocosm study where primary producers were exp

Objective: To clarify the preclinical stage of Alzheimer’s disease by estimating when β-amyloid accumulation first becomes associated with changes in cognition. Methods: Here we studied a large group (N = 4432) of cognitively unimpaired individuals who were screened for inclusion in the A4 trial (age 65–85) to assess the effect of subthreshold levels of β-amyloid on cognition and to identify which

Background: Long-term outcomes of patients admitted to intensive care units (ICUs) after surgery are unknown. We investigated the long-term effects of surgical exposure prior to ICU admission. Methods: Registry-based cohort study. The adjusted effect of surgical exposure for mortality was examined using Cox regression. Secondary analysis with conditional logistic regression in a case-control subpo

This chapter discusses the key aspects of engineered nanomaterial (ENM) toxicity. The individual properties of ENMs affecting their toxic potential are described, with a special focus on size, shape, and surface charge and functionalization. We present empirical evidence from a range of in vitro and in vivo studies showing potential adverse effects induced via inhalation, ingestion, or skin contac

For any positive natural number r\in\N^+ we construct new explicit proper r-harmonic functions on the celebrated 3-dimensional Thurston geometries Sol, Nil, SL_2(R)$, H^2*\rn and and S^2*R