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Bacterial infections of the respiratory tract contribute to exacerbations and disease progression in chronic obstructive pulmonary disease (COPD). There is also an increased risk of invasive pneumococcal disease in COPD. The underlying mechanisms are not fully understood but include impaired mucociliary clearance and structural remodeling of the airways. In addition, antimicrobial proteins that ar

Introduction The previously reported randomised controlled trial of a consensus regimen of pulse cyclophosphamide suggested that it was as effective as a daily oral (DO) cyclophosphamide for remission induction of antineutrophil cytoplasm autoantibodies-associated systemic vasculitis when both were combined with the same glucocorticoid protocol (CYCLOPS study (Randomised trial of daily oral versus

I investigate the consequences of long-run persistence of a society's preferences for cultural goods. Historical cultural activity is approximated with the frequency of births of music composers during the Renaissance and is linked with contemporary measures of cultural activity in Italian provinces. Areas with a 1% higher number of composer births nowadays show an up to 0.29% higher supply of cla

Theoretical and simulation investigations of viruses attaining icosahedral shape based on molecular models have recently become an exciting and rapidly growing research area. We discuss recent studies addressing the packing of the genome inside the capsid, thermodynamics, and the self-assembly of capsids. Special attention is given to the different packing of double-stranded and single-stranded po

The use of hypoxic air venting system as fire protection is increasing and is sometimes used to replace traditional extinguishing systems. An oxygen level of 15% is generally used because a lower concentration could pose serious health risks. On the request of the Swedish Radiation Safety Authority, a literature review was conducted to determine advantages and challenges with the system and furthe

This paper presents the elaboration of an experimentally validated model of a continuous cross-flow atomic layer deposition (ALD) reactor with temporally separated precursor pulsing encoded in the Modelica language. For the experimental validation of the model, in situ quartz crystal microbalance (QCM) diagnostics was used to yield submonolayer resolution of mass deposition resulting from thin fil

The solid state structure of endo,endo-bicyclo[3.3.1]nonane-2,6-diol, rac-2, shows a hydrogen bonded, three-connected, chiral 3D-net with utg-topology, distinctively different from those formed by the so called tubuland diols, e.g. 2,6-dimethylbicyclo[3.3.1]nonane-exo2, exo-6-diol, rac-5, that crystallise as three-connected, chiral etanets and from the qtz-net formed by weaker hydrogen bonds in th

Abstract is not available

Objectives: Core CSF changes in Alzheimer disease (AD) are decreased amyloid beta(1-42), increased total tau, and increased phospho-tau, probably indicating amyloid plaque accumulation, axonal degeneration, and tangle pathology, respectively. These biomarkers identify AD already at the predementia stage, but their diagnostic performance might be affected by age-dependent increase of AD-type brain

Naturvårdsverket fastställde 2006-12-21 ett åtgärdsprogram för hotade åkerogräs (Kloth 2007). Där rekommenderas att de rödlistade arterna inventeras i varje län, att deras status bedöms och att förslag ges till åkrar där arterna aktivt kan vidmakthållas (s.k. allmogeåkrar).

The continuous high demand of water resources for agricultural uses in Jordan is leading to a water crisis. A possible partial solution may be to import food which requires large amounts of water to grow instead of cultivating high water consuming crops. Crops such as banana and citrus cause a huge virtual water loss, which can be reduced by cultivating other less water-demanding crops. This paper

The role of the intermediate filament protein desmin in hypertrophy of smooth muscle was examined in desmin deficient mice (Des -/-). A partial obstruction of the urethra was created and after 9-19 days bladder weight increased about 3-fold in both Des -/- and wild type (Des +/+) animals. Bladder growth was associated with synthesis of actin and myosin. In the hypertrophic Des +/+ bladder the rela

The purpose of this study was to develop a computer-assisted diagnosis (CAD) system based on image-processing techniques and artificial neural networks for the interpretation of bone scans performed to determine the presence or absence of metastases. METHODS: A training group of 810 consecutive patients who had undergone bone scintigraphy due to suspected metastatic disease were included in the st